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1.发明授权SUBSTITUTED BENZOFURAN COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES 有权取代的苯并呋喃化合物及其用于治疗病毒疾病的方法
公开(公告)号：EP2753611B1
公开(公告)日：2018-04-11
申请号：EP12829739.7
申请日：2012-08-16
发明人： MCCOMAS, Casey Cameron , LIVERTON, Nigel J. , HABERMANN, Joerg , KOCH, Uwe , NARJES, Frank , LI, Peng , PENG, Xuanjia , SOLL, Richard , WU, Hao , PALANI, Anandan , DAI, Xing , LIU, Hong , HE, Shuwen , DANG, Qung
IPC分类号： C07D405/04 , C07D405/14 , C07D471/04 , C07D473/00 , C07D498/04 , A61K31/343 , A61K45/06 , A61K31/4045 , A61K31/416 , A61K31/4184 , A61K31/4375 , A61K31/4439 , A61K31/52 , A61P31/12 , A61P31/14
CPC分类号： C07D405/04 , A61K31/4045 , A61K31/416 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4439 , A61K31/4985 , A61K31/5025 , A61K31/52 , A61K45/06 , C07D405/14 , C07D471/04 , C07D473/00 , C07D487/04 , C07D498/04 , Y02A50/387 , Y02A50/389 , Y02A50/395 , A61K2300/00
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
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2.发明公开
公开(公告)号：EP2753611A1
公开(公告)日：2014-07-16
申请号：EP12829739.7
申请日：2012-08-16
发明人： MCCOMAS, Casey Cameron , LIVERTON, Nigel J. , HABERMANN, Joerg , KOCH, Uwe , NARJES, Frank , LI, Peng , PENG, Xuanjia , SOLL, Richard , WU, Hao , PALANI, Anandan , DAI, Xing , LIU, Hong , HE, Shuwen , DANG, Qung
IPC分类号： C07D307/83 , C07D307/82 , C07D405/04 , C07D405/14 , A61K31/343 , A61P31/12 , A61P31/14
CPC分类号： C07D405/04 , A61K31/4045 , A61K31/416 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4439 , A61K31/4985 , A61K31/5025 , A61K31/52 , A61K45/06 , C07D405/14 , C07D471/04 , C07D473/00 , C07D487/04 , C07D498/04 , Y02A50/387 , Y02A50/389 , Y02A50/395 , A61K2300/00
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
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3.发明公开
公开(公告)号：EP2753618A1
公开(公告)日：2014-07-16
申请号：EP12829730.6
申请日：2012-08-16
发明人： MCCOMAS, Casey Cameron , LIVERTON, Nigel J. , HABERMANN, Joerg , KOCH, Uwe , NARJES, Frank , LI, Peng , PENG, Xuanjia , SOLL, Richard , WU, Hao , PALANI, Anandan , DAI, Xing , LIU, Hong , HE, Shuwen , LAI, Zhong , DANG, Qung , ZORN, Nicholas
IPC分类号： C07D413/14 , C07D405/14 , A61K31/343 , A61P31/14
CPC分类号： A61K31/4245 , A61K31/433 , A61K31/4439 , A61K31/444 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/5365 , A61K31/5377 , A61K31/5383 , A61K31/695 , A61K45/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D498/04 , C07D513/04 , C07F7/10 , Y02A50/385 , Y02A50/387 , Y02A50/389 , A61K31/424 , A61K2300/00
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
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4.发明公开TETRACYCLIC HETEROCYCLE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES 审中-公开四环和杂环衍生物AND METHOD FOR USE IN病毒病的治疗
公开(公告)号：EP2753325A1
公开(公告)日：2014-07-16
申请号：EP12830590.1
申请日：2012-08-20
发明人： MCCOMAS, Casey Cameron , LIVERTON, Nigel J. , HABERMANN, Joerg , KOCH, Uwe , NARJES, Frank , LI, Peng , PENG, Xuanjia , SOLL, Richard , WU, Hao , PALANI, Anandan , HE, Shuwen , DAI, Xing , LIU, Hong , LAI, Zhong , LONDON, Clare , XIAO, Dong , ZORN, Nicolas , NARGUND, Ravi
IPC分类号： A61K31/343 , C07D307/82 , C07D405/10 , A61P31/14
CPC分类号： A61K31/553 , A61K31/407 , A61K31/437 , A61K31/519 , A61K31/5365 , A61K45/06 , C07D491/052 , C07D491/147 , C07D498/04 , C07D498/14 , C07D498/22 , Y02A50/387 , Y02A50/389 , Y02A50/395 , A61K2300/00
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
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5.发明授权
公开(公告)号：EP2753325B1
公开(公告)日：2018-09-19
申请号：EP12830590.1
申请日：2012-08-20
发明人： MCCOMAS, Casey Cameron , LIVERTON, Nigel J. , HABERMANN, Joerg , KOCH, Uwe , NARJES, Frank , LI, Peng , PENG, Xuanjia , SOLL, Richard , WU, Hao , PALANI, Anandan , HE, Shuwen , DAI, Xing , LIU, Hong , LAI, Zhong , LONDON, Clare , XIAO, Dong , ZORN, Nicolas , NARGUND, Ravi
IPC分类号： A61K31/343 , C07D307/82 , C07D405/10 , A61P31/14
CPC分类号： A61K31/553 , A61K31/407 , A61K31/437 , A61K31/519 , A61K31/5365 , A61K45/06 , C07D491/052 , C07D491/147 , C07D498/04 , C07D498/14 , C07D498/22 , Y02A50/387 , Y02A50/389 , Y02A50/395 , A61K2300/00
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
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6.发明授权HETEROCYCLIC-SUBSTITUED BENZOFURAN DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES 有权杂环取代的苯并呋喃衍生物及其用于治疗病毒疾病的方法
公开(公告)号：EP2753618B1
公开(公告)日：2018-04-11
申请号：EP12829730.6
申请日：2012-08-16
发明人： MCCOMAS, Casey Cameron , LIVERTON, Nigel J. , HABERMANN, Joerg , KOCH, Uwe , NARJES, Frank , LI, Peng , PENG, Xuanjia , SOLL, Richard , WU, Hao , PALANI, Anandan , DAI, Xing , LIU, Hong , HE, Shuwen , LAI, Zhong , DANG, Qung , ZORN, Nicholas
IPC分类号： C07D413/14 , C07D405/14 , A61K31/343 , A61P31/14
CPC分类号： A61K31/4245 , A61K31/433 , A61K31/4439 , A61K31/444 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/5365 , A61K31/5377 , A61K31/5383 , A61K31/695 , A61K45/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D498/04 , C07D513/04 , C07F7/10 , Y02A50/385 , Y02A50/387 , Y02A50/389 , A61K31/424 , A61K2300/00
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
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公开(公告)号：EP2542545A1
公开(公告)日：2013-01-09
申请号：EP11750145.2
申请日：2011-03-02
发明人： MCCOMAS, Casey, Cameron , LIVERTON, Nigel, J. , SOLL, Richard , LI, Peng , PENG, Xuanjia , WU, Hao , NARJES, Frank , HABERMANN, Joerg , KOCH, Uwe , LIU, Shilan
IPC分类号： C07D307/84 , C07D405/04 , C07D405/10 , A61K31/343 , A61P31/14
CPC分类号： C07D307/84 , A61K31/343 , A61K45/06 , C07D405/04 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/12 , C07D409/10 , C07D413/04 , C07D413/10 , C07D413/14 , C07D417/10 , C07D471/04 , C07D473/00 , C07D487/04 , C07D491/04 , C07D495/04 , C07D498/04 , C07D513/04 , A61K2300/00
摘要： Disclosed are compounds of formula (I) that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
摘要翻译： 所公开的是用作丙型肝炎病毒（HCV）NS5B聚合酶抑制剂的式（I）化合物，这些化合物的合成，以及这些化合物用于抑制HCV NS5B聚合酶活性的用途，用于治疗或预防HCV感染和用于抑制 在基于细胞的系统中HCV病毒复制和/或病毒产生。
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