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公开(公告)号:EP4146297A1
公开(公告)日:2023-03-15
申请号:EP21732410.2
申请日:2021-04-30
申请人: Mexbrain , UNIVERSITE CLAUDE BERNARD - LYON 1 , Centre National de la Recherche Scientifique (CNRS) , Institut National de la Santé et de la Recherche Médicale (INSERM) , Institut Gustave Roussy (IGR) , Vetagro-Sup Institut d'Enseignement Superieur et de Recherche
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公开(公告)号:EP4247428A1
公开(公告)日:2023-09-27
申请号:EP21824615.5
申请日:2021-11-19
申请人: NH THERAGUIX , UNIVERSITE CLAUDE BERNARD - LYON 1 , Mexbrain , Centre National de la Recherche Scientifique (CNRS) , Institut National de la Santé et de la Recherche Médicale (INSERM) , Hospices Civils de Lyon , Institut National de la Recherche pour l'Agriculture, l'Alimentation et l'Environnement
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公开(公告)号:EP4031180A1
公开(公告)日:2022-07-27
申请号:EP20771594.7
申请日:2020-09-18
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公开(公告)号:EP3914298A1
公开(公告)日:2021-12-01
申请号:EP20705243.2
申请日:2020-01-24
申请人: Mexbrain , UNIVERSITE CLAUDE BERNARD - LYON 1 , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
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公开(公告)号:EP3727350A1
公开(公告)日:2020-10-28
申请号:EP18842805.6
申请日:2018-12-21
申请人: Mexbrain , UNIVERSITE CLAUDE BERNARD - LYON 1 , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS-
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6.
公开(公告)号:EP4188966A1
公开(公告)日:2023-06-07
申请号:EP21759335.9
申请日:2021-07-29
申请人: Mexbrain , Centre National de la Recherche Scientifique (CNRS) , UNIVERSITE CLAUDE BERNARD - LYON 1
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公开(公告)号:EP4247435A1
公开(公告)日:2023-09-27
申请号:EP21824616.3
申请日:2021-11-19
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公开(公告)号:EP3795178A1
公开(公告)日:2021-03-24
申请号:EP19306138.9
申请日:2019-09-19
申请人: NH THERAGUIX , Institut Gustave Roussy , UNIVERSITE CLAUDE BERNARD - LYON 1 , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- , INSERM (Institut National de la Santé et de la Recherche Médicale) , Universite Paris-Sud
IPC分类号: A61K41/00 , A61K47/69 , A61K49/18 , A61P35/00 , A61P1/16 , A61P9/10 , A61P11/00 , A61P37/08 , A61K39/00 , A61N5/10
摘要: The present disclosure relates to the field of nanomedicine, in particular for treating cancers. The present disclosure more specifically provides new methods of treating undesirable M2-polarized macrophages and/or inducing M1 macrophage polarization in a subject in need thereof, comprising administering to said subject a therapeutically effective amount of nanoparticles containing metallic elements.
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9.
公开(公告)号:EP3402535A1
公开(公告)日:2018-11-21
申请号:EP17700370.4
申请日:2017-01-13
申请人: Institut National de la Santé et de la Recherche Médicale (INSERM) , Université Claude Bernard Lyon 1 , Université de Paris 5 René Descartes , Centre National de la Recherche Scientifique , Ecole Nationale Superieure de Chimie de Paris
发明人: MIGNET, Nathalie , DOAN, Bich-Thuy , RAMNICEANU, Grégory , TILLEMENT, Olivier , SANCEY GALLIOT, Lucie , LUX, François , SEGUIN, Johanne
CPC分类号: A61K51/065 , A61K49/128 , A61K49/1881 , A61K51/1244
摘要: The invention relates to a novel use of ultrafine nanoparticles as an imaging agent in a method for diagnosing a renal disorder. The invention also relates to the use of ultrafine nanoparticles as an imaging agent in methods for monitoring the therapeutic effectiveness of a renal disorder treatment. Said nanoparticles include: (i) a polyorganosiloxane matrix (POS); (ii) one or more chelating agents grafted onto the POS matrix by -Si-C- covalent bonding; and (iii) one or more metal ions chelated by one or more of the aforementioned chelating agents.
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公开(公告)号:EP4412623A1
公开(公告)日:2024-08-14
申请号:EP22797426.8
申请日:2022-10-03
申请人: Mexbrain , UNIVERSITE CLAUDE BERNARD - LYON 1 , Centre National de la Recherche Scientifique , Institut National des Sciences Appliquees de Lyon (Insa Lyon) , Université Jean Monnet Saint-Étienne
发明人: TILLEMENT, Olivier , LUX, François , GREA, Thomas , GRANGE, Coralie , AIGLE, Axel , ROUDIER, Anouk , DAVID, Laurent , MONTEMBAULT, Alexandra , TILLEMENT, Augustin , PASSIEUX, Renaud , SALAZAR ARIZA, Juan Felipe
IPC分类号: A61K31/722 , C08B37/08 , C08L5/08
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