公开(公告)号：EP2892870A1

公开(公告)日：2015-07-15

申请号：EP13728300.8

申请日：2013-05-31

申请人： Micromidas, Inc.

发明人： SMITH, Ryan, L. ,  BISSELL, John ,  MASUNO, Makoto, N. ,  CANNON, Douglas ,  WOOD, Alex, B. ,  FOSTER, Marc

IPC分类号： C07C67/03 ,  C07C67/31 ,  C07C69/533 ,  C07C69/675 ,  C07C69/732 ,  C07C1/24 ,  C07C11/167 ,  C07C51/16 ,  C07C57/15 ,  C07C29/09

CPC分类号： C07C67/31 ,  C07C1/24 ,  C07C29/095 ,  C07C29/149 ,  C07C51/16 ,  C07C67/03 ,  C07C67/30 ,  C07C2527/167 ,  C07C69/675 ,  C07C69/533 ,  C07C11/167 ,  C07C57/15 ,  C07C69/56 ,  C07C31/207

摘要： Provided herein are methods that utilize polyhydroxyalkanoates (PHAs) as a substrate for further conversion to C4 and C5 compounds. Polyhydroxyalkanoates can undergo esterification to yield alkyl hydroxyalkanoates and alkyl alkenoates, which may serve as useful precursors in the production of alkadienes and alkenedioic acids, including for example butadiene and butenedioic acid.

摘要翻译： 本文提供了利用聚羟基链烷酸酯（PHA）作为进一步转化为C4和C5化合物的底物的方法。 聚羟基链烷酸酯可经历酯化以产生羟基链烷酸烷基酯和链烯酸烷基酯，其可用作生产链二烯和链烯二酸（包括例如丁二烯和丁烯二酸）的有用前体。

公开(公告)号：EP2970167A2

公开(公告)日：2016-01-20

申请号：EP14773258.0

申请日：2014-03-12

申请人： Micromidas, Inc.

发明人： BROWNING, Shawn, M. ,  MASUNO, Makoto, N. ,  BISSELL, John ,  NICHOLSON, Benjamin, F. ,  HIRSCH-WEIL, Dimitri, A. ,  SMITH, Ryan, L.

IPC分类号： C07D307/18

CPC分类号： C07D307/46 ,  C07D307/18 ,  C07D307/48

摘要： Provided are solid forms of 5-(halomethyl)furfural, including a crystalline form of 5- (chloromethyl)furfural. Provided are also methods for preparing solid forms of 5- (halomethyl)furfural by crystallization using certain solvents.

摘要翻译： 提供5-（卤代甲基）糠醛的固体形式，包括5-（氯甲基）糠醛的结晶形式。 还提供了通过使用某些溶剂进行结晶来制备5-（卤代甲基）糠醛的固体形式的方法。

公开(公告)号：EP2766328A1

公开(公告)日：2014-08-20

申请号：EP12778834.7

申请日：2012-09-14

申请人： Micromidas, Inc.

发明人： MASUNO, Makoto, N. ,  CANNON, Douglas ,  BISSELL, John ,  SMITH, Ryan, L. ,  FOSTER, Marc ,  WOOD, Alex, Benjamin ,  SMITH, Patrick, B. ,  HUCUL, Dennis A.

IPC分类号： C07C15/08 ,  C07C2/52

CPC分类号： C07C51/16 ,  C07C2/52 ,  C07C2/862 ,  C07C2/865 ,  C07C15/08 ,  C07C2521/18 ,  C07C2527/02 ,  C07C2527/053 ,  C07C2527/08 ,  C07C2527/10 ,  C07C2527/122 ,  C07C2527/126 ,  C07C2527/128 ,  C07C2527/132 ,  C07C2527/133 ,  C07C2527/135 ,  C07C2527/138 ,  C07C2527/14 ,  C07C2527/16 ,  C07C2529/08 ,  C07C2529/14 ,  C07C2529/24 ,  C07C2531/02 ,  C07C2531/04 ,  C07C2531/12 ,  C07C15/06

摘要： The present disclosure provides methods to produce para-xylene, toluene, and other compounds from renewable sources (e.g., cellulose, hemicellulose) and ethylene in the presence of an acid, such as a Lewis acid. For example, cellulose and/or hemicellulose may be converted into 2,5-dimethylfuran (DMF) and 2-methylfuran, which may be converted into para-xylene and toluene, respectively. In particular, para-xylene can then be oxidized to form terephthalic acid.

公开(公告)号：EP3046914A1

公开(公告)日：2016-07-27

申请号：EP14845176.8

申请日：2014-09-19

申请人： Micromidas, Inc.

发明人： WOOD, Alex, B. ,  MASUNO, Makoto, N. ,  SMITH, Ryan, L. ,  BISSELL, John ,  HIRSCH-WEIL, Dimitri, A. ,  ARAIZA, Robert, Joseph ,  HENTON, Daniel, R. ,  PLONKA, James, H.

IPC分类号： C07D307/48 ,  C07D307/50 ,  B01J27/06

CPC分类号： C07D307/46 ,  B01J27/10 ,  C07D307/50

摘要： The present disclosure provides methods to produce 5-(halomethyl)furfural, including 5- (chloromethyl)furfural, by acid-catalyzed conversion of C6 saccharides, including isomers thereof, polymers thereof, and certain derivatives thereof. The methods make use of acids with lower concentrations, and allows for conversion of sugars into 5-(halomethyl)furfural at higher temperatures and faster reaction or residence times.

公开(公告)号：EP2646563A1

公开(公告)日：2013-10-09

申请号：EP11791730.2

申请日：2011-11-29

申请人： Micromidas, Inc.

发明人： SMITH, Ryan, L. ,  BISSELL, John ,  MCGRATH, Casey

IPC分类号： C12P7/62 ,  C12R1/01

CPC分类号： C12R1/01 ,  C12P7/625

摘要： The present disclosure relates to isolated bacterial strains producing polyhydroxyalkanoate (PHA), microbial consortia including such strains, and cultures of such strains and microbial consortia. In particular, the present disclosure relates to compositions including such strains, microbial consortia, and cultures and methods of use thereof.

公开(公告)号：EP2970171B1

公开(公告)日：2019-12-11

申请号：EP14776137.3

申请日：2014-03-12

申请人： Micromidas, Inc.

发明人： WOOD, Alex, B. ,  BROWNING, Shawn, M. ,  MASUNO, Makoto, N. ,  SMITH, Ryan, L. ,  BISSELL, John ,  HIRSCH-WEIL, Dimitri, A.

IPC分类号： C07D307/48 ,  C07D315/00 ,  B01D53/00

公开(公告)号：EP2917193A1

公开(公告)日：2015-09-16

申请号：EP13789647.8

申请日：2013-10-25

申请人： Micromidas, Inc.

发明人： BROWNING, Shawn, M. ,  BISSELL, John ,  SMITH, Ryan, L. ,  MASUNO, Makoto, N. ,  NICHOLSON, Benjamin, F. ,  WOOD, Alex, B.

IPC分类号： C07D307/50

CPC分类号： C07D307/50

摘要： The present disclosure provides methods to produce 5-(halomethyl)furfural, including 5- (chloromethyl)furfural, by acid-catalyzed conversion of biomass. The methods make use of certain organic solvents with temperature-dependent solubility for 5-(halomethyl)furfural. This allows for temperature-dependent phase separation of the 5-(halomethyl)furfural from the reaction mixture. In certain embodiments, solid 5-(halomethyl)furfural may be obtained. The solid 5-(halomethyl)furfural obtained may be amorphous or crystalline.

公开(公告)号：EP2718275A1

公开(公告)日：2014-04-16

申请号：EP12733249.2

申请日：2012-06-06

申请人： Micromidas, Inc.

发明人： MASUNO, Makoto, N. ,  BISSELL, John ,  SMITH, Ryan, L. ,  HIGGINS, Brian ,  WOOD, Alex, Benjamin ,  FOSTER, Marc

IPC分类号： C07D307/46 ,  C07D307/50 ,  C12P17/04

CPC分类号： C07D307/50 ,  C07D307/46

摘要： The present disclosure provides methods to produce substituted furans (
e.g. , halomethylfurfural, hydroxymethylfurfural, and furfural), by acid-catalyzed conversion of biomass using a gaseous acid in a multiphase reactor, such as a fluidized bed reactor.

公开(公告)号：EP2970171A1

公开(公告)日：2016-01-20

申请号：EP14776137.3

申请日：2014-03-12

申请人： Micromidas, Inc.

发明人： WOOD, Alex, B. ,  BROWNING, Shawn, M. ,  MASUNO, Makoto, N. ,  SMITH, Ryan, L. ,  BISSELL, John ,  HIRSCH-WEIL, Dimitri, A.

IPC分类号： C07D307/48 ,  C07D315/00 ,  B01D53/00

摘要： The present disclosure provides methods for purifying a 5-(halomethyl)furfural composition, including 5-(chloromethyl)furfural, at operating conditions that decrease or minimize the decomposition or degradation of 5-(chloromethyl)furfural during the process. The methods may employ certain solvents, operating conditions, and/or techniques (e.g., gas stripping). The gaseous 5-(halomethyl)furfural produced from the process can be condensed or deposited to yield 5-(halomethyl)furfural in liquid or solid form. The solid 5-(halomethyl)furfural may be amorphous or crystalline.

摘要翻译： 本公开内容提供了在减少或最小化过程期间5-（氯甲基）糠醛的分解或降解的操作条件下纯化包括5-（氯甲基）糠醛的5-（卤代甲基）糠醛组合物的方法。 该方法可以使用某些溶剂，操作条件和/或技术（例如气提）。 由该方法产生的气态5-（卤代甲基）糠醛可以被冷凝或沉积以产生液体或固体形式的5-（卤代甲基）糠醛。 固体5-（卤代甲基）糠醛可以是无定形的或结晶的。