摘要:
A composition, suitable for use in producing hydrogel polymer films from which biomedical devices such as contact lenses can be made, comprising at least one hydrophilic silicone macromer. In one aspect, a hydrophilic silicone macromer is of the Formula 1 : X-Si(R 1 )(R 2 )0-(Si(R 3 )(R 4 )0) a -Si(R 5 )(R 6 )-Y (1) wherein R 1 , R 2 , R 3 R 4 , R 5 and R 6 are independently selected from a monovalent linear, branched, or cyclic radical with 1 to 50 carbon atoms, that can optionally contain a heteroatom or I; I is R L - R P ; Y is a free radical polymerization-effective hydrophilic group with the general structure :R L - R P -Z; R L is a linking residue from a non-isomerizable hydrosilylation effective terminal olefin comprising the general structure -CH 2 -C(R b R 7 )-(CR 8 R 9 ) n , the subscript n is selected from integers from 1 to 10; R 7 , R 8 , and R 9 can be selected from hydrogen and a mono-valent hydrocarbon radical with 1 to 10 carbon atoms that optionally contain a heteroatom; R b is selected from a monovalent hydrocarbon radical with 1 to 6 carbon atoms; RP is a spacer group comprising a diavelant hydrophilic organic radical with 0 to 100 carbon atoms and optionally contains heteroatoms, and X is a free radical polymerizable group. The said composition can be polymers and films suitable for use in making contact lenses.
摘要:
The present invention relates to a fast curing compositions comprising a (meth)acrylamide functionalized hydrophilic silicone monomers having a polyether moiety containing a branched linking group. In one embodiment, such compositions are useful for preparing water-absorbing silicone-hydrogel films for contact lens applications. In one embodiment, the (meth)acrylamide monomers disclosed here have a branched linking group on the polyether moiety which makes it possible to produce hydrophilic polyether modified silicone copolymers without the need to separate various by-products including, but not limited to, unreacted, isomerized polyether and associated high molecular weight by-products.