HYDROPHILIC MACROMERS AND HYDROGELS COMPRISING THE SAME
    4.
    发明公开
    HYDROPHILIC MACROMERS AND HYDROGELS COMPRISING THE SAME 审中-公开
    亲水性大分子单体和SO水凝胶

    公开(公告)号:EP2828337A2

    公开(公告)日:2015-01-28

    申请号:EP13764258.3

    申请日:2013-03-06

    IPC分类号: C08L83/14

    摘要: A composition, suitable for use in producing hydrogel polymer films from which biomedical devices such as contact lenses can be made, comprising at least one hydrophilic silicone macromer. In one aspect, a hydrophilic silicone macromer is of the Formula 1 : X-Si(R
    1 )(R
    2 )0-(Si(R
    3 )(R
    4 )0)
    a -Si(R
    5 )(R
    6 )-Y (1) wherein R
    1 , R
    2 , R
    3 R
    4 , R
    5 and R
    6 are independently selected from a monovalent linear, branched, or cyclic radical with 1 to 50 carbon atoms, that can optionally contain a heteroatom or I; I is R
    L - R
    P ; Y is a free radical polymerization-effective hydrophilic group with the general structure :R
    L - R
    P -Z; R
    L is a linking residue from a non-isomerizable hydrosilylation effective terminal olefin comprising the general structure -CH
    2 -C(R
    b R
    7 )-(CR
    8 R
    9 )
    n , the subscript n is selected from integers from 1 to 10; R
    7 , R
    8 , and R
    9 can be selected from hydrogen and a mono-valent hydrocarbon radical with 1 to 10 carbon atoms that optionally contain a heteroatom; R
    b is selected from a monovalent hydrocarbon radical with 1 to 6 carbon atoms; RP is a spacer group comprising a diavelant hydrophilic organic radical with 0 to 100 carbon atoms and optionally contains heteroatoms, and X is a free radical polymerizable group. The said composition can be polymers and films suitable for use in making contact lenses.