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    Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same
    1.
    发明公开
    Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same 失效
    咪唑ivate ivate ivate。。。。。。。。。。。。。。。。。。。。。

    公开(公告)号：EP0412529A1

    公开(公告)日：1991-02-13

    申请号：EP90115236.3

    申请日：1990-08-08

    申请人： NIPPON CHEMIPHAR CO., LTD.

    发明人： Okabe, Susumu, 287-5, Shingoryouguchi-cho ,  Masaki, Mitsuo ,  Yamakawa, Tomio ,  Matsukura, Hitoshi ,  Nomura, Yustaka

    IPC分类号： C07D233/84 ,  A61K31/415

    CPC分类号： C07D233/84

    摘要： Disclosed are novel imidazole derivatives having the formula:
    wherein R¹ is hydrogen or an alkyl group having 1-6 carbon atoms, R² is an alkyl group having 2-6 carbon atoms substi­tuted with an alkoxy group having 1-4 carbon atoms, each of R³, R⁴, R⁵ and R⁶ independently is hydrogen, a halogen, an alkyl group having 1-6 carbon atoms, an alkoxy group having 1-6 carbon atoms, a fluorine-substituted alkyl group having 1-6 carbon atoms, or a fluorine-substituted alkoxy group having 1-6 carbon atoms. The new imidazole derivatives are effective particularly as anti-ulcer agents.

    摘要翻译： 公开了具有下式的新型咪唑衍生物：其中R 1是氢或具有1-6个碳原子的烷基，其中R 2是具有2-6个碳原子的烷基， 1-4个碳原子，R 3，R 4，R 5和R 6各自独立地是氢，卤素，具有1-6个碳原子的烷基，具有1- 6个碳原子，具有1-6个碳原子的氟取代的烷基或具有1-6个碳原子的氟取代的烷氧基。 新的咪唑衍生物特别有效地用作抗溃疡剂。