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公开(公告)号:EP0625507A3
公开(公告)日:1994-11-30
申请号:EP94303568.3
申请日:1994-05-19
发明人: Sueda, Noriyoshi, c/o Nisshin Flour Milling Co. , Yamada, Kazuhiko, c/o Nisshin Flour Milling Co. , Yanai, Makoto, c/o Nisshin Flour Milling Co. , Miura, Katsutoshi, c/o Nisshin Flour Milling Co. , Horigome, Masato, c/o Nisshin Flour Milling Co. , Oshida, Norio, c/o Nisshin Flour Milling Co. , Hiramoto, Shigeru, c/o Nisshin Flour Milling Co. , Katsuyama, Koichi, c/o Nisshin Flour Milling Co. , Nakata, Fumihisa, c/o Nisshin Flour Milling Co. , Kinoshita, Nobuhiro, c/o Nisshin Flour Milling Co. , Tsukada, Yoko, c/o Nisshin Flour Milling Co.
IPC分类号: C07C275/32 , A61K31/17 , C07C275/34 , C07D307/52 , C07D295/13 , C07D211/58 , C07D317/58 , C07D295/215 , C07D211/16 , C07D213/40 , C07D295/20 , C07D295/12
CPC分类号: C07D213/40 , A61K9/1623 , A61K9/2018 , A61K9/4866 , C07C275/32 , C07C275/34 , C07C323/44 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2601/20 , C07C2602/10 , C07C2602/22 , C07C2603/74 , C07D207/14 , C07D209/08 , C07D209/16 , C07D211/16 , C07D211/22 , C07D211/42 , C07D211/48 , C07D211/56 , C07D211/58 , C07D211/60 , C07D213/75 , C07D213/82 , C07D215/08 , C07D217/06 , C07D231/12 , C07D233/56 , C07D249/08 , C07D265/30 , C07D295/13 , C07D295/135 , C07D295/215 , C07D295/26 , C07D307/52 , C07D317/58 , C07D333/20 , C07D401/06 , C07D401/12 , C07D451/04 , C07D453/02 , C07D471/04 , C07D471/08 , C07D491/10 , Y10S514/824
摘要: Urea derivatives of formula (I)
wherein the valuable groups are as defined in the specification, which possess both an ACAT inhibitory activity and an antioxidative activity. Those derivatives are useful in the prophylaxis and treatment of hypercholesterolemia and atherosclerosis.摘要翻译: 式(I)的尿素衍生物,其中有价基团如说明书中所定义,同时具有ACAT抑制活性和抗氧化活性。 这些衍生物可用于预防和治疗高胆固醇血症和动脉粥样硬化。
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2.Urea derivatives and their use as acat inhibitors 失效
标题翻译: 尿素衍生物Verwendung als ACAT-hemmenden Verbindungen公开(公告)号:EP0625507B1
公开(公告)日:1997-07-23
申请号:EP94303568.3
申请日:1994-05-19
发明人: Sueda, Noriyoshi, c/o Nisshin Flour Milling Co. , Yamada, Kazuhiko, c/o Nisshin Flour Milling Co. , Yanai, Makoto, c/o Nisshin Flour Milling Co. , Miura, Katsutoshi, c/o Nisshin Flour Milling Co. , Horigome, Masato, c/o Nisshin Flour Milling Co. , Oshida, Norio, c/o Nisshin Flour Milling Co. , Hiramoto, Shigeru, c/o Nisshin Flour Milling Co. , Katsuyama, Koichi, c/o Nisshin Flour Milling Co. , Nakata, Fumihisa, c/o Nisshin Flour Milling Co. , Kinoshita, Nobuhiro, c/o Nisshin Flour Milling Co. , Tsukada, Yoko, c/o Nisshin Flour Milling Co.
IPC分类号: C07C275/32 , A61K31/17 , C07C275/34 , C07D307/52 , C07D295/13 , C07D211/58 , C07D317/58 , C07D295/215 , C07D211/16 , C07D213/40 , C07D295/20 , C07D295/12
CPC分类号: C07D213/40 , A61K9/1623 , A61K9/2018 , A61K9/4866 , C07C275/32 , C07C275/34 , C07C323/44 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2601/20 , C07C2602/10 , C07C2602/22 , C07C2603/74 , C07D207/14 , C07D209/08 , C07D209/16 , C07D211/16 , C07D211/22 , C07D211/42 , C07D211/48 , C07D211/56 , C07D211/58 , C07D211/60 , C07D213/75 , C07D213/82 , C07D215/08 , C07D217/06 , C07D231/12 , C07D233/56 , C07D249/08 , C07D265/30 , C07D295/13 , C07D295/135 , C07D295/215 , C07D295/26 , C07D307/52 , C07D317/58 , C07D333/20 , C07D401/06 , C07D401/12 , C07D451/04 , C07D453/02 , C07D471/04 , C07D471/08 , C07D491/10 , Y10S514/824
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3.Urea derivatives and their use as acat inhibitors 失效
标题翻译: 尿素衍生物Verwendung als ACAT-hemmenden Verbindungen。公开(公告)号:EP0625507A2
公开(公告)日:1994-11-23
申请号:EP94303568.3
申请日:1994-05-19
发明人: Sueda, Noriyoshi, c/o Nisshin Flour Milling Co. , Yamada, Kazuhiko, c/o Nisshin Flour Milling Co. , Yanai, Makoto, c/o Nisshin Flour Milling Co. , Miura, Katsutoshi, c/o Nisshin Flour Milling Co. , Horigome, Masato, c/o Nisshin Flour Milling Co. , Oshida, Norio, c/o Nisshin Flour Milling Co. , Hiramoto, Shigeru, c/o Nisshin Flour Milling Co. , Katsuyama, Koichi, c/o Nisshin Flour Milling Co. , Nakata, Fumihisa, c/o Nisshin Flour Milling Co. , Kinoshita, Nobuhiro, c/o Nisshin Flour Milling Co. , Tsukada, Yoko, c/o Nisshin Flour Milling Co.
IPC分类号: C07C275/32 , A61K31/17 , C07C275/34 , C07D307/52 , C07D295/13 , C07D211/58 , C07D317/58 , C07D295/215 , C07D211/16 , C07D213/40 , C07D295/20 , C07D295/12
CPC分类号: C07D213/40 , A61K9/1623 , A61K9/2018 , A61K9/4866 , C07C275/32 , C07C275/34 , C07C323/44 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2601/20 , C07C2602/10 , C07C2602/22 , C07C2603/74 , C07D207/14 , C07D209/08 , C07D209/16 , C07D211/16 , C07D211/22 , C07D211/42 , C07D211/48 , C07D211/56 , C07D211/58 , C07D211/60 , C07D213/75 , C07D213/82 , C07D215/08 , C07D217/06 , C07D231/12 , C07D233/56 , C07D249/08 , C07D265/30 , C07D295/13 , C07D295/135 , C07D295/215 , C07D295/26 , C07D307/52 , C07D317/58 , C07D333/20 , C07D401/06 , C07D401/12 , C07D451/04 , C07D453/02 , C07D471/04 , C07D471/08 , C07D491/10 , Y10S514/824
摘要: Urea derivatives of formula (I)
wherein the valuable groups are as defined in the specification, which possess both an ACAT inhibitory activity and an antioxidative activity. Those derivatives are useful in the prophylaxis and treatment of hypercholesterolemia and atherosclerosis.摘要翻译: 式(I)的脲衍生物
其中有价值基团如说明书中所定义,其具有ACAT抑制活性和抗氧化活性。 这些衍生物可用于预防和治疗高胆固醇血症和动脉粥样硬化。
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