GENE GROUP APPLICABLE TO CANCER PROGNOSTICATION
    2.
    发明公开
    GENE GROUP APPLICABLE TO CANCER PROGNOSTICATION 审中-公开
    AUF DIE KREBSPROGNOSTIZIERUNG ANWENDBARE GENGRUPPE

    公开(公告)号:EP1983046A4

    公开(公告)日:2009-03-25

    申请号:EP07707949

    申请日:2007-02-02

    IPC分类号: C12N15/00 C12N15/09 C12Q1/68

    CPC分类号: C12Q1/6886 C12Q2600/158

    摘要: It is intended to provide a novel method for determining the possibility of lymph node metastasis of breast cancer using a difference of expression level of a specific gene between a human metastatic breast cancer tissue (or cell) and a nonmetastatic breast cancer tissue (or cell) as an index. For this purpose, the method characterized by: (1) measuring the expression level of a gene having a specific base sequence in a human metastatic breast cancer tissue (or cell); (2) measuring the expression level of the gene in a human nonmetastatic breast cancer tissue (or cell); and (3) comparing the measured values of (1) and (2) and determining the possibility of lymph node metastasis of breast cancer based on the difference is provided.

    摘要翻译: 本发明旨在提供一种使用人转移性乳腺癌组织(或细胞)和非转移性乳腺癌组织(或细胞)之间特定基因的表达水平差异来确定乳腺癌淋巴结转移可能性的新方法, 作为索引。 为此,所述方法的特征在于:(1)测量人转移性乳腺癌组织(或细胞)中具有特定碱基序列的基因的表达水平; (2)测量人非转移性乳腺癌组织(或细胞)中基因的表达水平; (3)比较(1)和(2)的测量值并基于该差异确定乳腺癌的淋巴结转移的可能性。

    METHOD OF DETECTING MAMMARY CANCER CELLS
    3.
    发明公开
    METHOD OF DETECTING MAMMARY CANCER CELLS 审中-公开
    检测方法的乳腺癌细胞

    公开(公告)号:EP2128621A4

    公开(公告)日:2011-05-18

    申请号:EP07707909

    申请日:2007-02-01

    IPC分类号: G01N33/574

    CPC分类号: G01N33/57415

    摘要: The present invention provides a novel method for detecting mammary cancer cells which uses, as an index, an expression level of a specific gene in human mammary cancer tissue (or cells). The method is characterized by including (1) measuring an expression level of a gene having a specific nucleotide sequence in human mammary cancer tissue (or cells), (2) measuring an expression level of the gene in human normal mammary gland tissue (or cells), and (3) detecting mammary cancer cells on the basis of the difference between measurement values obtained in (1) and (2).