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29 条记录 (耗时 0.019 秒)

    Oral Film-Form Base And Preparation
    6.
    发明公开
    Oral Film-Form Base And Preparation 有权
    Orale folienformende Basis und Herstellung

    公开(公告)号：EP2626064A1

    公开(公告)日：2013-08-14

    申请号：EP13000089.6

    申请日：2013-01-09

    申请人： NITTO DENKO CORPORATION

    发明人： Asari, Daisuke ,  Hori, Mitsuhiko ,  Shishido, Takuya

    IPC分类号： A61K9/70

    CPC分类号： A61K9/0007 ,  A61K9/006 ,  A61K47/02

    摘要： The present invention provides an oral film-form base which has a rapid dissolution profile in the mouth and sufficient film strength, and gives an improved taking property by foaming in the mouth. The oral film-form base includes an edible polymer soluble both in water and in an organic solvent having a solubility parameter of 9.7 or higher, a foaming agent, and an auxiliary foaming agent, wherein the foaming agent is foamable in the presence of water, and the foaming agent and the auxiliary foaming agent each are insoluble in the organic solvent, have an average particle size of 0.1 to 60 µm, and are included in particle states.

    摘要翻译： 本发明提供一种在口中具有快速溶出曲线并具有足够的膜强度的口腔膜形底，并通过在口中发泡获得改善的吸收性。 口腔膜型基质包括可溶于水和可溶性参数为9.7以上的有机溶剂中的可食性聚合物，发泡剂和辅助发泡剂，其中发泡剂在水的存在下是可发泡的， 发泡剂和辅助发泡剂各自不溶于有机溶剂，平均粒径为0.1〜60μm，并且以粒子状态包含。

    Pharmaceutical allergen composition and method for producing the same
    7.
    发明公开
    Pharmaceutical allergen composition and method for producing the same 审中-公开
    Pharmazeutische Allergenzusammensetzung und Herstellungsverfahrendafür

    公开(公告)号：EP2614817A1

    公开(公告)日：2013-07-17

    申请号：EP13000090.4

    申请日：2013-01-09

    申请人： NITTO DENKO CORPORATION

    发明人： Shishido, Takuya ,  Asari, Daisuke ,  Hori, Mitsuhiko

    IPC分类号： A61K9/16 ,  A61K9/20 ,  A61K9/50

    CPC分类号： A61K47/36 ,  A61K9/0056 ,  A61K9/19 ,  A61K38/168 ,  A61K39/36 ,  A61K47/26 ,  A61K47/32

    摘要： The present invention provides a pharmaceutical composition capable of preserving and delivering an allergen having poor thermal stability without using gelatin as a stabilizer, and a method for producing the pharmaceutical composition.
    The present invention provides a pharmaceutical composition containing an allergen and additives selected from at least two groups from among group (A) consisting of polysaccharides having high formability; group (B) consisting of mono- to hexasaccharides, sugar alcohols thereof, maltodextrin, and polyvinylpyrrolidone; and group (C) consisting of viscous polysaccharides; wherein the additives have a stabilizing effect on the allergen.

    摘要翻译： 本发明提供能够保存并输送热稳定性差的变应原剂而不使用明胶作为稳定剂的药物组合物及其制造方法。 本发明提供一种含有变应原和添加剂的药物组合物，所述组合物选自由成形性高的多糖组成的组（A）中的至少两组; 由一至六糖组成的组（B），其糖醇，麦芽糖糊精和聚乙烯吡咯烷酮; 和由粘性多糖组成的（C）组; 其中所述添加剂对变应原具有稳定作用。