公开(公告)号：EP1551427A4

公开(公告)日：2007-05-23

申请号：EP03766819

申请日：2003-06-16

申请人： NOVACAL PHARMACEUTICALS INC

发明人： BERNARD SUZANNE ,  O'REILLY JACK ,  BASSIRI MANSOUR ,  NAMDAR NADER ,  NAJAFI RAMIN

IPC分类号： A01N59/00 ,  A61K9/00 ,  A61K31/74 ,  A61K33/14 ,  A61K33/24 ,  A61K33/30 ,  A61K33/40 ,  C01B11/04 ,  C02F1/461

CPC分类号： C01B11/04 ,  A01N59/00 ,  A61K9/0048 ,  A61K31/74 ,  A61K33/14 ,  A61K33/24 ,  A61K33/30 ,  A61K33/40 ,  C02F1/4618 ,  C02F2001/46185 ,  C02F2103/026 ,  C02F2201/46115 ,  C02F2201/4618 ,  C02F2209/04 ,  C02F2209/06 ,  C02F2303/04 ,  A01N2300/00 ,  A61K2300/00

摘要： Described herein is a physiologically-balanced, acidic solution. Typically the solution is prepared by a chemical reactions or by the electrolysis of a solution s comprising a mixture of an inorganic salt to form a physiologically balanced solution. This invention also relates to methods for use of the solutions, including a specialized bandage which may be used in combination with the solutions, or optionally with other topically applied materials. A mixture of inorganic salts and, optionally minerals, is used in order to mimic the electrolyte concentration and mixture of body fluid in an isotonic state. The solution typically comprises of one halide salt of lithium, sodium, potassium, calcium, and other cations. Typically the halide is fluoride, chloride, bromide, or iodide, and most typically chloride. A typical electrolyzed solution of the present invention has a pH within the range of about 2 to about 5, an oxidation reduction potential within the range of about +600 mV to about +1200 mV, and hypohalous acid concentration in the range of about 10 ppm to about 200 ppm. The solution has bactericidal, fungicidal, and sporicidal properties. The composition of the invention is nontoxic and has antibacterial properties, and is useful in any application in which antimicrobial properties are desirable.