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1.发明授权COMBINATION COMPRISING A SIGNAL TRANSDUCTION INHIBITOR AND AN EPOTHILONE DERIVATIVE 有权组合中包含信号传导和A抑制剂的埃坡霉素衍生物
公开(公告)号：EP1385522B1
公开(公告)日：2009-06-24
申请号：EP02744903.2
申请日：2002-02-26
申请人： NOVARTIS AG , Novartis Pharma GmbH
发明人： BUCHDUNGER, Elisabeth , HELDIN, Carl-Henrik , ÖSTMAN, Arne , PIETRAS, Kristian , O'REILLY, Terence , ROTHERMEL, John, David , TRAXLER, Peter , WARTMANN, Markus , BRANDT, Ralf
IPC分类号： A61K31/505 , A61K45/06 , A61K31/425 , A61P35/00
CPC分类号： A61K31/505 , A61K31/425 , A61K45/06 , A61K31/435 , A61K2300/00
摘要： The present invention relates to a combination comprising N-{5-[4-(4-methyl-piperazino-methyl) -benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine and an epothiione derivative; pharmaceutical composition comprising said combination; method of treatment comprising said combination; and commercial packages comprising said combination.
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2.发明公开COMBINATION COMPRISING A SIGNAL TRANSDUCTION INHIBITOR AND AN EPOTHILONE DERIVATIVE 有权组合中包含信号传导和A抑制剂的埃坡霉素衍生物
公开(公告)号：EP1385522A2
公开(公告)日：2004-02-04
申请号：EP02744903.2
申请日：2002-02-26
申请人： Novartis AG , Novartis Pharma GmbH
发明人： BUCHDUNGER, Elisabeth , HELDIN, Carl-Henrik , ÖSTMAN, Arne , PIETRAS, Kristian , O'REILLY, Terence , ROTHERMEL, John, David , TRAXLER, Peter , WARTMANN, Markus , BRANDT, Ralf
IPC分类号： A61K31/505 , A61K45/06 , A61K31/425 , A61P35/00
CPC分类号： A61K31/505 , A61K31/425 , A61K45/06 , A61K31/435 , A61K2300/00
摘要： The present invention relates to a combination comprising N-{5-[4-(4-methyl-piperazino-methyl) -benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine and an epothiione derivative; pharmaceutical composition comprising said combination; method of treatment comprising said combination; and commercial packages comprising said combination.
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