公开(公告)号：EP0648214A1

公开(公告)日：1995-04-19

申请号：EP93912675.0

申请日：1993-06-02

申请人： NOVO NORDISK A/S

发明人： BREINHOLT, Jens ,  LANGE, Lene

IPC分类号： A23K1 ,  A01N43 ,  A01N63 ,  A23L3 ,  A61K31 ,  B27K3 ,  C07D307 ,  C09D7 ,  C12P17

CPC分类号： C07D307/34 ,  A01N43/08 ,  A01N63/04 ,  C12P17/04 ,  C12R1/645 ,  Y10S435/911

摘要： Compounds having formula (3), wherein R1 is hydrogen, straight or branched alkyl with 1-10 carbon atoms, straight or branched alkenyl with 2-10 carbon atoms, straight or branched alkynyl with 2-10 carbon atoms, benzyl or aryl, optionally mono- or plurisubstituted with straight or branched alkyl with 1-10 carbon atoms, hydroxy, alkoxy, halogen, an amino or a nitro group; and when R1 is H salts thereof, or R1 is acyl (R?1 = -COR2¿) wherein R2 is straight or branched alkyl with 1-10 carbon atoms, alkenyl with 2-10 carbon atoms, alkynyl with 2-10 carbon atoms, or aryl, optionally mono- or plurisubstituted with alkyl with 1-10 carbon atoms, hydroxy, alkoxy, halogen, an amino or a nitro group. Compounds of formula (3) have interesting antifungal activities and may, accordingly, be used as active ingredients in fungicidal compositions.

公开(公告)号：EP0815209A1

公开(公告)日：1998-01-07

申请号：EP96905762.0

申请日：1996-03-18

申请人： NOVO NORDISK A/S

发明人： SCHÜLEIN, Martin ,  ANDERSEN, Lene, Nonboe ,  LASSEN, S ren, Flensted ,  KAUPPINEN, Markus, Sakari ,  LANGE, Lene ,  NIELSEN, Ruby, Ilum ,  IHARA, Michiko Novo Nordisk Bioindustry Ltd. ,  TAKAGI, Shinobu Novo Nordisk Bioindustry Ltd.

IPC分类号： C12N15 ,  C05F11 ,  C05F17 ,  C07G99 ,  C11D3 ,  C12N1 ,  C12N9 ,  C12S3 ,  C12S11 ,  D06M13 ,  D06M16 ,  D06P5 ,  D21C5 ,  D21H11 ,  D21H21 ,  C12R1 ,  D21H17

CPC分类号： C12N9/2437 ,  A61K38/00 ,  C05F11/08 ,  C05F17/0036 ,  C07K2319/00 ,  C11D3/386 ,  C12P19/14 ,  C12Y302/01004 ,  D06M16/003 ,  D06P5/02 ,  D06P5/158 ,  D21C5/005 ,  D21H17/005 ,  D21H21/10 ,  Y02P20/145 ,  Y02W30/43

摘要： An enzyme preparation consisting essentially of an enzyme having cellulolytic activity and comprising a first amino acid sequence of 14 residues having the sequence Thr Arg X3 X4 Asp Cys Cys X8 X9 X10 Cys X12 Trp X14, in which X3 and X4 independently is Trp, Tyr or Phe; X8 is Arg, Lys or His; each of X9, X10, X12 and X13 is any of the 20 naturally occurring amino acid residues; and a second amino acid sequence of 5 residues having the sequence Trp Cys Cys XX4 Cys, in which XX4 is any of the 20 naturally occurring amino acid residues with the proviso that, in the first amino acid sequence, (i) when X12 is Ser, then X14 is not Ser, and (ii) when X12 is Gly, then X14 is not Ala; performs excellently in detergent, laundering, textile and papermaking pulp applications.

公开(公告)号：EP0799307A1

公开(公告)日：1997-10-08

申请号：EP95941608.0

申请日：1995-12-22

申请人： NOVO NORDISK A/S

发明人： LANGE, Lene ,  NIELSEN, Jack, Bech ,  SCHÜLEIN, Martin

IPC分类号： C12N9 ,  C11D3 ,  C11D11 ,  C12S3 ,  C12S11 ,  D06M16 ,  D06P5 ,  D21C5 ,  D21C9 ,  D21H17 ,  D21H21 ,  C12R1

CPC分类号： D21H21/10 ,  C11D3/38645 ,  D06M16/003 ,  D06P5/02 ,  D06P5/158 ,  D21C5/005 ,  D21C5/027 ,  D21H17/005 ,  Y02W30/648

摘要： A detergent composition comprising an enzyme preparation with substantial cellulytic activity, especially endoglucanase activity, at alkaline conditions which enzyme composition is derived from or producible by a fungus selected from the Basidiomycetous families Coprinaceae and Bolbitiaceae, preferably from the group of strains belonging to the genera Psathyrella, Podaxis, Panaeolus, Coprinus and Bolbitius and a method for providing a stone-washed look to textiles, especially to cellulosic fabric such as denim, using the mentioned enzyme preparation; and a method for improving the drainage of paper pulp or the de-inking of recycled paper using the mentioned enzyme preparation; and an enzyme preparation with substantial cellulytic activity at alkaline conditions which enzyme composition is derived from or producible by a fungus selected from the Basidiomycetous families Coprinaceae and Bolbitiaceae, provided that the fungus does not belong to the species Coprinus cinereus.

公开(公告)号：EP0523158A1

公开(公告)日：1993-01-20

申请号：EP91907783.0

申请日：1991-04-05

申请人： NOVO NORDISK A/S ,  FERROSAN FINE CHEMICALS A/S

发明人： DAMTOFT, Sören ,  SVENDSEN, Nannette ,  LANGE, Lene

IPC分类号： A01N33

CPC分类号： A01N33/12 ,  A01N57/12 ,  A01N47/20 ,  A01N47/14 ,  A01N47/12 ,  A01N37/46 ,  A01N2300/00

摘要： L'invention se rapporte à l'utilisation de certains sels d'ammonium quaternaire à chaînes trés longues bien connus, tels que des sels d'ammonium n-alkyltriméthyle (ATAX), des sels d'ammonium alkylbenzyle-diméthyle (AKX) et des sels d'ammonium dialkyldiméthyle (DADAX), représentés par les formules générales I, II et III, respectivement, où R représente un alkyle ou un alkylène à chaîne droite ou ramifiée ayant plus de 17 atomes de carbone, R' représente un alkyle ou un alkylène à chaîne droite ou ramifiée ayant plus de 11 atomes de carbone, et X représente un anion d'halogène, d'acétate, de sulfate ou de phosphate, de phytotoxicité faible dans la protection des plantes en vue de limiter et de combattre la prolifération des champignons. On décrit également des compositions fongicides contenant de tels composés soit seuls soit combinés à d'autres agents à action fongicide, des procédés servant à limiter ou à combattre la prolifération des champignons dans des plantes par l'application de ces compositions aux plantes, et l'utilisation de ces composés comme additifs dans des compositions fongicides.

公开(公告)号：EP0652899A1

公开(公告)日：1995-05-17

申请号：EP93914657.0

申请日：1993-07-09

申请人： NOVO NORDISK A/S

发明人： PEDERSEN, Anders Hjelholt ,  HALKIER, Torben ,  NIELSEN, Birte, Annette ,  LANGE, Lene ,  MIKKELSEN, Jan, Moeller ,  RASMUSSEN, Grethe ,  HANSEN, Mogens, Trier

IPC分类号： C12N15 ,  A01N37 ,  A01N63 ,  A61K38 ,  A61P31 ,  C07H21 ,  C07K14 ,  C12N1 ,  C12P21 ,  C12R1

CPC分类号： A01N63/04 ,  A61K38/00 ,  C07K14/37

摘要： A DNA construct comprising a DNA sequence encoding an antifungal polypeptide, which sequence comprises the nucleotide sequence shown in SEQ ID No. 1 or an analogue thereof, which i) hybridizes with a DNA sequence comprising the nucleotide sequence shown in SEQ ID No. 1, or with a probe hybridizing with the nucleotide sequence SEQ ID No. 1, ii) encodes a polypeptide which reacts with an antibody reactive with at least one epitope of the polypeptide having the amino acid sequence shown in SEQ ID No. 2, and/or iii) encodes a polypeptide having the amino acid sequence shown in the appended SEQ ID No. 2 or a sequence homologous thereto, provided that the DNA sequence is different from one which encodes the polypeptide having the amino acid sequence shown in SEQ ID No. 2 except for an asparagine in position 4, an alanine in position 24, a lysine in position 32, a phenylalanine in position 42 and a tyrosine in position 50. The antifungal polypeptide encoded by the DNA construct may be used for combating or controlling fungal infections, in particular on plants.