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    METHOD FOR FABRICATING MICROARRAYS OF SOFT MATERIALS
    2.
    发明公开
    METHOD FOR FABRICATING MICROARRAYS OF SOFT MATERIALS 有权
    VERFAHREN ZUR HERSTELLUNG VON MIKROARRAYS AUS WEICHEN MATERIALIEN

    公开(公告)号：EP2594941A1

    公开(公告)日：2013-05-22

    申请号：EP12763427.7

    申请日：2012-03-27

    申请人： NTT Docomo, Inc. ,  The University of Tokyo

    发明人： HIYAMA, Satoshi ,  KURIBAYASHI, Kaori ,  ONOE, Hiroaki ,  TAKEUCHI, Shoji

    IPC分类号： G01N33/543 ,  C12M1/00 ,  C12N15/09 ,  G01N37/00

    CPC分类号： B05D1/325 ,  B01J2219/00317 ,  B01J2219/00529 ,  B01J2219/00637 ,  B01J2219/00659 ,  B01J2219/00722 ,  B01J2219/00725 ,  B81B2201/0214 ,  B81B2201/058 ,  B81C1/00206 ,  C12N15/09 ,  G01N33/543 ,  G01N37/00

    摘要： A method for fabricating a microarray of plural kinds of soft materials using a poly(paraxylylene) resin lift-off method, includes: a process of vapor-depositing a poly(para-xylylene) resin of a first layer on a substrate, forming a first micro pattern in the poly(para-xylylene) resin of the first layer; obtaining a substrate on which a first microarray is formed by pouring a solution of a first soft material, freeze-drying the first soft material so as to obtain a micro-arrayed substrate of the freeze-dried first soft material; a process of vapor-depositing a poly(para-xylylene) resin of a second layer on the micro-arrayed substrate of the freeze-dried first soft material, forming a second micro pattern in a place different from the first micro pattern by penetrating the poly(para-xylylene) resin of the first layer and the second layer, forming a second microarray on the substrate by pouring a solution including a second soft material; and a process of forming a microarray of the first and the second soft materials on the same substrate by peeling off the poly(para-xylylene) resin of the first layer and the second layer.

    摘要翻译： 使用聚（对二甲苯）树脂剥离法制造多种软质材料的微阵列的方法包括：在基材上蒸镀第一层的聚（对二甲苯）树脂的方法，形成 第一层聚（对二甲苯）树脂中的第一微图案; 通过倾倒第一软质材料的溶液获得形成有第一微阵列的基板，冷冻干燥第一软质材料，得到冷冻干燥的第一软质材料的微阵列基板; 在冷冻干燥的第一软质材料的微阵列基底上气相沉积第二层的聚（对二甲苯）树脂的方法，在不同于第一微图案的位置上形成第二微图形， 聚（对二甲苯）树脂和第二层，通过倾倒包含第二软材料的溶液在基材上形成第二微阵列; 以及通过剥离第一层和第二层的聚（对二甲苯）树脂，在同一基板上形成第一和第二软质材料的微阵列的工艺。

    METHOD OF FORMING ARTIFICIAL LIPID FILM OVER MINUTE HOLE IN SUBSTRATE AND SUBSTRATE HAVING THE ARTIFICIAL LIPID FILM
    3.
    发明公开
    METHOD OF FORMING ARTIFICIAL LIPID FILM OVER MINUTE HOLE IN SUBSTRATE AND SUBSTRATE HAVING THE ARTIFICIAL LIPID FILM 审中-公开
    法形成人工脂质薄膜关于小孔衬底和衬底，人工脂质膜的

    公开(公告)号：EP2216647A1

    公开(公告)日：2010-08-11

    申请号：EP08854654.4

    申请日：2008-11-26

    申请人： The University of Tokyo

    发明人： TAKEUCHI, Shoji ,  KURIBAYASHI, Kaori

    IPC分类号： G01N27/333 ,  B01J13/04 ,  G01N27/416 ,  G01N33/544

    CPC分类号： G01N33/48728 ,  A61K9/1277

    摘要： There is provided a method of preparing organic-solvent-free artificial lipid membranes formed over microapertures of a substrate and a substrate for holding the artificial lipid membranes. The method of preparing artificial lipid membranes over microapertures of a substrate includes forming a lipid pattern 5 on the perimeter of microapertures 4 formed in a substrate 1, swelling the lipid pattern 5 by an electroformation method, fusing the swelled lipid pattern, and further swelling the fused lipid pattern for each microaperture to prepare dome-shaped organic-solvent-free lipid membranes 7.

    摘要翻译： 提供了一种制备在基片形成microapertures和基板无有机溶剂的人工脂质膜，用于保持人工脂质膜的方法。 在基板的microapertures制备人工脂质膜的方法包括：在一个基片1而形成microapertures 4的周边形成的脂质图案5，通过在电形成方法肿胀脂质图案5，熔融的溶胀脂质图案，并且进一步溶胀 对于每个microaperture制备圆顶状有机溶剂无脂膜融合脂质图案7