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公开(公告)号：EP3513837A1
公开(公告)日：2019-07-24
申请号：EP17850960.0
申请日：2017-09-14
申请人： National University Corporation Kobe University , Kanai Juyo Kogyo Co., Ltd. , Alfresa Pharma Corporation
摘要： Disclosed is a spacer for radiotherapy that can be easily compressed into a reduced thickness, and has a high capacity to reconstitute itself from a compressed state back to its initial thickness after removal of external force. The spacer for radiotherapy is a flexible structure having front and back main faces and thickness therebetween, and composed of strands of biocompatible and biodegradable synthetic fibers, wherein the spacer consists of (a) a pair of main face portions opposing each other with a gap therebetween and respectively defining the main faces of the structure, and (b) a linker portion linking between the pair of main face portions, (c) wherein the main face portions comprise a knitted-fabric structure or a weave structure made of the strands, and (d) wherein the linker portion is composed as a collection of linker strands formed of the said strands and respectively extending in the thickness direction of the spacer and linking the pair of main face portions with each other.
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公开(公告)号：EP2497534A1
公开(公告)日：2012-09-12
申请号：EP10828230.2
申请日：2010-10-28
申请人： National University Corporation Kobe University , Kanai Juyo Kogyo Co., Ltd. , Alfresa Pharma Corporation
IPC分类号： A61N5/10
CPC分类号： A61N5/10 , A61B2090/0445 , A61B2090/0815 , A61N2005/1094 , A61N2005/1096 , G21F1/10 , G21F3/00
摘要： Provided is a spacer for ionizing radiation therapy, which can be easily disposed in a living body, does not require abdominal surgery for removing the disposed spacer after radiation therapy, and can effectively separate a tissue to be treated from other tissues. The spacer for ionizing radiation therapy includes a fiber assembly obtained by three-dimensionally entangling a fibrous material formed of a biocompatible synthetic polymeric material. Specifically, the spacer has a thickness of 1 mm to 100 mm.
摘要翻译： 本发明提供一种电离放射治疗用间隔物，其可以容易地设置在生物体中，不需要腹部手术去除放射线治疗后的配置间隔物，能够有效地将待治疗的组织与其他组织分离。 用于电离辐射治疗的间隔物包括通过三维缠绕由生物相容性合成聚合物材料形成的纤维材料获得的纤维组合物。 具体而言，间隔物的厚度为1mm〜100mm。
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公开(公告)号：EP2497534B1
公开(公告)日：2016-08-10
申请号：EP10828230.2
申请日：2010-10-28
申请人： National University Corporation Kobe University , Kanai Juyo Kogyo Co., Ltd. , Alfresa Pharma Corporation
CPC分类号： A61N5/10 , A61B2090/0445 , A61B2090/0815 , A61N2005/1094 , A61N2005/1096 , G21F1/10 , G21F3/00
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公开(公告)号：EP3095483A1
公开(公告)日：2016-11-23
申请号：EP14874083.0
申请日：2014-12-24
申请人： National University Corporation Kobe University , Alfresa Pharma Corporation , Kanai Juyo Kogyo Co., Ltd.
发明人： FUKUMOTO, Takumi , SASAKI, Ryohei , MORIHARA, Tsutomu , SASAI, Yoshio , FURUTA, Yoshihisa , OBATA, Tsutomu , TAGAMI, Yoshitaka
CPC分类号： A61N5/10 , A61B90/04 , A61B2090/0436 , A61B2090/0815 , A61L31/06 , A61L31/14 , A61L31/146 , A61L31/148 , A61L31/18 , A61N5/1049 , A61N2005/1094 , A61N2005/1096 , G21F3/00 , C08L67/04
摘要： A radiotherapy spacer is disclosed that has both flexibility for allowing it to gently cover the organs of various shapes along their surfaces and pressure resistance for preventing itself from being crushed under the pressure between organs and thus enabling it to retain its own shape and continuously ensure the therapeutic space. The spacer comprises a fiber assembly formed of entangled biocompatible fibers, which may be bioabsorbable, such as nonwoven fabric, and is characterized in that the density of the fiber assembly is 0.05 g/cm 3 to 0.2 g/cm 3 .
摘要翻译： 公开了一种放射治疗间隔物，其具有允许其轻轻地覆盖沿其表面的各种形状的器官和耐压性的柔性，以防止其在器官之间的压力下被压碎，从而使其能够保持其自身的形状并且连续地确保 治疗空间。 间隔物包括由络合的生物相容性纤维形成的纤维集合体，其可以是生物可吸收的，例如非织造织物，其特征在于纤维集合体的密度为0.05g / cm 3至0.2g / cm 3。
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