公开(公告)号：EP3513837A1

公开(公告)日：2019-07-24

申请号：EP17850960.0

申请日：2017-09-14

申请人： National University Corporation Kobe University ,  Kanai Juyo Kogyo Co., Ltd. ,  Alfresa Pharma Corporation

发明人： SASAKI, Ryohei ,  FUKUMOTO, Takumi ,  INUBUSHI, Sachiko ,  OBATA, Tsutomu ,  TAGAMI, Yoshitaka

IPC分类号： A61N5/10 ,  A61L31/06

摘要： Disclosed is a spacer for radiotherapy that can be easily compressed into a reduced thickness, and has a high capacity to reconstitute itself from a compressed state back to its initial thickness after removal of external force. The spacer for radiotherapy is a flexible structure having front and back main faces and thickness therebetween, and composed of strands of biocompatible and biodegradable synthetic fibers, wherein the spacer consists of (a) a pair of main face portions opposing each other with a gap therebetween and respectively defining the main faces of the structure, and (b) a linker portion linking between the pair of main face portions, (c) wherein the main face portions comprise a knitted-fabric structure or a weave structure made of the strands, and (d) wherein the linker portion is composed as a collection of linker strands formed of the said strands and respectively extending in the thickness direction of the spacer and linking the pair of main face portions with each other.

公开(公告)号：EP3095483A1

公开(公告)日：2016-11-23

申请号：EP14874083.0

申请日：2014-12-24

申请人： National University Corporation Kobe University ,  Alfresa Pharma Corporation ,  Kanai Juyo Kogyo Co., Ltd.

发明人： FUKUMOTO, Takumi ,  SASAKI, Ryohei ,  MORIHARA, Tsutomu ,  SASAI, Yoshio ,  FURUTA, Yoshihisa ,  OBATA, Tsutomu ,  TAGAMI, Yoshitaka

IPC分类号： A61N5/10 ,  A61L31/00

CPC分类号： A61N5/10 ,  A61B90/04 ,  A61B2090/0436 ,  A61B2090/0815 ,  A61L31/06 ,  A61L31/14 ,  A61L31/146 ,  A61L31/148 ,  A61L31/18 ,  A61N5/1049 ,  A61N2005/1094 ,  A61N2005/1096 ,  G21F3/00 ,  C08L67/04

摘要： A radiotherapy spacer is disclosed that has both flexibility for allowing it to gently cover the organs of various shapes along their surfaces and pressure resistance for preventing itself from being crushed under the pressure between organs and thus enabling it to retain its own shape and continuously ensure the therapeutic space. The spacer comprises a fiber assembly formed of entangled biocompatible fibers, which may be bioabsorbable, such as nonwoven fabric, and is characterized in that the density of the fiber assembly is 0.05 g/cm 3 to 0.2 g/cm 3 .

摘要翻译： 公开了一种放射治疗间隔物，其具有允许其轻轻地覆盖沿其表面的各种形状的器官和耐压性的柔性，以防止其在器官之间的压力下被压碎，从而使其能够保持其自身的形状并且连续地确保 治疗空间。 间隔物包括由络合的生物相容性纤维形成的纤维集合体，其可以是生物可吸收的，例如非织造织物，其特征在于纤维集合体的密度为0.05g / cm 3至0.2g / cm 3。

公开(公告)号：EP2537530A1

公开(公告)日：2012-12-26

申请号：EP11744693.0

申请日：2011-02-17

申请人： National University Corporation Kobe University

发明人： OGINO, Chiaki ,  TANAKA, Tsutomu ,  SASAKI, Ryohei ,  KONDO, Akihiko

IPC分类号： A61K41/00 ,  A61K9/10 ,  A61K33/40 ,  A61K39/395 ,  A61K47/02 ,  A61K47/32 ,  A61K47/34 ,  A61K47/48 ,  A61P29/00 ,  A61P31/12 ,  A61P35/00

CPC分类号： A61K9/0019 ,  A61K33/40 ,  A61K41/0057 ,  A61K47/6835 ,  A61K2039/505 ,  A61N5/10 ,  A61N2005/1098 ,  C07K16/2863 ,  Y10T428/2982

摘要： Provided is a radiotherapeutic agent, comprising a composite particle, which is obtained by binding a molecule that specifically recognizes a target to a substrate particle comprising titanium peroxide, and which generates reactive oxygen through irradiation with a radiation. Further, because the radiotherapeutic agent contains the molecule that specifically recognizes a target, the radiotherapeutic agent has a function of accumulating in the target. The radiotherapeutic agent is capable of enhancing effects of radiotherapy, and is capable of reducing side effects on a living body to efficiently attack the target.

摘要翻译： 本发明提供一种放射治疗剂，其包含复合颗粒，其通过将特异性识别靶标的分子与包含过氧化钛的底物颗粒结合而获得，并且通过辐射照射产生活性氧。 此外，由于放射治疗剂含有特异性识别靶标的分子，所以放射治疗剂具有在目标物中累积的功能。 放射治疗剂能够增强放射疗法的作用，能够减轻对活体的副作用，以有效地攻击靶。

公开(公告)号：EP4115947A1

公开(公告)日：2023-01-11

申请号：EP21763541.6

申请日：2021-03-04

申请人： Nihon Yamamura Glass Co., Ltd. ,  National University Corporation Kobe University

发明人： KIMURA, Shuji ,  OGURA, Shinichiro ,  MIYAWAKI, Daisuke ,  MUKUMOTO, Naritoshi ,  SASAKI, Ryohei ,  MIYAZAKI, Satoru

IPC分类号： A61N5/10

摘要： Provided is a medical immobilization device that contributes to reducing the burden on a patient, while being capable of firmly immobilizing the patient. A medical immobilization device 10 is a device for immobilizing a specific site 1 of the body of a patient with the patient lying on their back. The medical immobilization device 10 comprises a block 3 made of a material that allows radiation to pass through, and the block 3 comprises holder portions 2a to 2c in which at least a region from the lower surface to both sides of the specific site 1 fit. All or part of the upper part of the block 3 is open.