-
1.发明公开N-ARYL-N-PIPERIDIN-4-YL-PROPIONAMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS 审中-公开N-芳基-N-哌啶-4-基 - 丙酰胺衍生物及其作为单胺神经递质再摄取抑制剂
公开(公告)号：EP2234616A1
公开(公告)日：2010-10-06
申请号：EP08861581.0
申请日：2008-12-18
申请人： NeuroSearch A/S
IPC分类号： A61K31/4468 , C07D211/58 , A61P25/04 , A61P25/06 , A61P25/18 , A61P25/24 , A61P25/22 , A61P25/28 , A61P25/16 , A61P25/32 , A61P25/34 , A61P25/36 , A61P19/02 , A61P19/10 , A61P3/04
CPC分类号： A61K31/4468 , C07D211/58
摘要： This invention relates to /\/-aryl-/\/-piperidin-4-yl-propionannide derivatives for use as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy, such as for the treatment of pain, and to pharmaceutical compositions comprising the compounds, and to novel compounds.
-
2.发明公开CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS 有权色烯-2-酮衍生物及其作为抑制剂MONOAMINNEUTROTRANSMITTERWIEDERAUFNAHME使用
公开(公告)号：EP2430020A1
公开(公告)日：2012-03-21
申请号：EP10716360.2
申请日：2010-05-06
申请人： NeuroSearch A/S
IPC分类号： C07D451/06 , A61K31/46
CPC分类号： C07D451/06 , A61K31/46
摘要： The present applications discloses novel 8-aza-bicyclo[3.2.1]oct-3-yloxy)- chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors. In other aspects the applications discloses the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
-
3.发明公开N-ARYL-N-PIPERIDIN-4-YL-PROPIONAMIDE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS 审中-公开N-芳基-N-哌啶-4-炔丙酰胺衍生物及其作为阿片受体配体的用途
公开(公告)号：EP2235006A1
公开(公告)日：2010-10-06
申请号：EP08861973.9
申请日：2008-12-18
申请人： NeuroSearch A/S
IPC分类号： C07D405/06 , A61K31/4468 , A61P25/00
CPC分类号： C07D405/06
摘要： This invention relates to novel /\/-aryl-/\/-piperidin-4-yl-propionamide derivatives useful as opioid receptor ligands. In other aspects the invention relates to the use of these compounds in a method for therapy, such as for the treatment of pain, and to pharmaceutical compositions comprising the compounds of the invention.
摘要翻译： 本发明涉及用作阿片受体配体的新的N-芳基-N-哌啶-4-基丙酰胺衍生物。 在其它方面，本发明涉及这些化合物在用于治疗的方法例如用于治疗疼痛的用途中的用途，以及涉及包含本发明化合物的药物组合物。
-
4.发明公开NOVEL TETRAMETHYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS 审中-公开新的四甲基取代的哌啶及其作为恢复MONO阿明EURO发射机的抑制剂
公开(公告)号：EP2313394A1
公开(公告)日：2011-04-27
申请号：EP09769245.3
申请日：2009-06-23
申请人： NeuroSearch A/S
IPC分类号： C07D401/12 , A61K31/4545 , A61K31/4709 , A61P25/24
CPC分类号： C07D401/12
摘要： This invention relates to novel tetramethyl substituted pipehdine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
-
5.发明授权1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS 有权1 PHENETHYLPIPERIDINDERIVATE及其作为阿片受体配体
公开(公告)号：EP1987001B1
公开(公告)日：2010-05-05
申请号：EP07726356.4
申请日：2007-02-13
申请人： NeuroSearch A/S
发明人： PETERS, Dan , ERIKSEN, Birgitte, L. , MUNRO, Gordon , NIELSEN, Elsebet, Østergaard , REDROBE, John, Paul
IPC分类号： C07D211/32 , C07D407/12 , A61K31/4525 , A61K31/445 , A61P25/00
CPC分类号： C07D211/26 , C07D405/12
摘要： This invention relates to novel 1-phenethylpiperidine derivatives of formuia (I) useful as opioid receptor ligands. More specifically, the invention provides compounds useful as μ opioid receptor ligands. In other aspects the invention relates to the use of these compounds in a method for therapy, such as for the treatment of pain, and to pharmaceutical compositions comprising the compounds of the invention.
-
6.发明公开N-ARYL-N-PIPERIDIN-4-YL-PROPIONAMIDE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS 审中-公开N-芳基-N-哌啶-4-基 - 丙酰胺衍生物及其AS阿片受体配体
公开(公告)号：EP2234972A1
公开(公告)日：2010-10-06
申请号：EP08862853.2
申请日：2008-12-18
申请人： NeuroSearch A/S
IPC分类号： C07D211/58 , A61K31/4468 , A61P1/00 , A61P1/10 , A61P13/00 , A61P25/04 , A61P25/24 , A61P25/30
CPC分类号： C07D211/58
摘要： This invention relates to novel N-aryl -N-piperidin-4 -yl -propionamide derivatives (I) useful as opioid receptor ligands. In other aspects the invention relates to the use of these compounds in a method for therapy, such as for the treatment of pain, and to pharmaceutical compositions comprising the compounds of the invention.
-
7.发明公开N-PIPERIDIN-4-YLMETHYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS 审中-公开N-哌啶-4-基甲基 - 酰胺衍生物及其作为单胺神经递质再摄取抑制剂的用途
公开(公告)号：EP2183219A2
公开(公告)日：2010-05-12
申请号：EP08786658.8
申请日：2008-07-31
申请人： NeuroSearch A/S
发明人： PETERS, Dan , ERIKSEN, Birgitte, L. , REDROBE, John, Paul , MUNRO, Gordon , NIELSEN, Elsebet, Østergaard
IPC分类号： C07D211/26 , C07D401/12
CPC分类号： C07D211/26 , C07D401/12
摘要： This invention relates to novel N-piperidin-4-ylmethyl amide derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy, and to pharmaceutical compositions comprising the compounds of the invention.
-
8.发明公开1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS 有权1 PHENETHYLPIPERIDINDERIVATE及其作为阿片受体配体
公开(公告)号：EP1987001A1
公开(公告)日：2008-11-05
申请号：EP07726356.4
申请日：2007-02-13
申请人： NeuroSearch A/S
发明人： PETERS, Dan , ERIKSEN, Birgitte, L. , MUNRO, Gordon , NIELSEN, Elsebet, Østergaard , REDROBE, John, Paul
IPC分类号： C07D211/32 , C07D407/12 , A61K31/4525 , A61K31/445 , A61P25/00
CPC分类号： C07D211/26 , C07D405/12
摘要： This invention relates to novel 1-phenethylpiperidine derivatives of formuia (I) useful as opioid receptor ligands. More specifically, the invention provides compounds useful as μ opioid receptor ligands. In other aspects the invention relates to the use of these compounds in a method for therapy, such as for the treatment of pain, and to pharmaceutical compositions comprising the compounds of the invention.
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.01 秒)
