-
1.发明公开ANTICANCER AGENT COMPRISING AMINOACETONITRILE COMPOUND AS ACTIVE INGREDIENT 审中-公开细菌对癌AMINOACETONITRILVERBINDUNG为活动
公开(公告)号：EP3043791A1
公开(公告)日：2016-07-20
申请号：EP14781682.1
申请日：2014-09-12
发明人： ANDOH, Nobuharu , SANPEI, Osamu , TOGA, Tetsuo , MORRIS, David Lawson , ASTON, Roger , TANAKA, Koji , HINO, Tomokazu
IPC分类号： A61K31/277 , A61K31/415 , A61P35/00
CPC分类号： A61K31/277 , A61K31/341 , A61K31/381 , A61K31/415 , A61K31/4196 , A61K31/42 , A61K31/421 , A61K31/4245 , A61K31/426 , A61K31/433 , A61K31/437 , A61K31/44 , A61K31/4965 , A61K31/505 , A61K31/5377 , A61K31/5383
摘要： wherein R1 is a hydrogen atom, an alkyl group and the like, R2, R3, and R4 are the same or different and each is a hydrogen atom, an alkyl group and the like, R5 and R6 are the same or different and each is a hydrogen atom, a halogen atom and the like, m is 0 or 1, R is a halogen atom, a cyano group, a nitro group, a phenyl group optionally substituted by an alkyl group and the like, an alkyl group and the like, Ar1 is a phenyl group, a naphthyl group, a pyridyl group, a pyrazolyl group, or the like, each of which is optionally substituted by a halogen atom, a cyano group, a nitro group, alkyl group and the like, and W is —O—, —S—, —SO2—, or —N(R7)—wherein R7 is a hydrogen atom, a (C1-C6) alkyl group and the like, or a pharmacologically acceptable salt thereof.
-
2.发明公开ANTI CANCER AGENT COMPRISING AMINOACETONITRILE COMPOUND AS ACTIVE INGREDIENT 审中-公开包含氨基乙腈化合物作为活性成分的抗癌剂
公开(公告)号：EP3261636A1
公开(公告)日：2018-01-03
申请号：EP16713115.0
申请日：2016-02-24
发明人： ANDOH, Nobuharu , SANPEI, Osamu , TOGA, Tetsuo , MORRIS, David Lawson , ASTON, Roger , TANAKA, Koji , HINO, Tomokazu
IPC分类号： A61K31/40 , A61K31/415 , A61K31/4192 , A61K31/4196 , A61K31/42 , A61K31/4245 , A61K31/425 , A61K31/433 , A61K31/44 , A61K31/4433 , A61K31/4436 , A61K31/496 , A61K31/4965 , A61K31/505 , A61K31/535 , A61P35/00
CPC分类号： A61K31/277 , A61K31/381 , A61K31/40 , A61K31/415 , A61K31/4192 , A61K31/4196 , A61K31/42 , A61K31/4245 , A61K31/425 , A61K31/433 , A61K31/437 , A61K31/44 , A61K31/4433 , A61K31/4436 , A61K31/496 , A61K31/4965 , A61K31/505 , A61K31/535 , A61K31/5383 , A61P35/00
摘要： The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and anticancer agent containing, as an active ingredient, an aminoacetonitrile compound represented by the formula (I) wherein R1 is a hydrogen atom, an alkyl group and the like, R2, R3, and R4 are the same or different and each is a hydrogen atom, an alkyl group and the like, R5 and R6 are the same or different and each is a hydrogen atom, a halogen atom and the like, m is 0 or 1, R is a halogen atom, a cyano group, a nitro group, a phenyl group optionally substituted by an alkyl group and the like, an alkyl group and the like, Ar1 is a phenyl group, a naphthyl group, a pyridyl group, a pyrazolyl group, or the like, each of which is optionally substituted by a halogen atom, a cyano group, a nitro group, alkyl group and the like, and W is -O-, -S-, -SO2-, or -N(R7)- wherein R7 is a hydrogen atom, a (C1-C6) alkyl group and the like, or a pharmacologically acceptable salt thereof.
-
公开(公告)号：EP3043791B1
公开(公告)日：2019-04-24
申请号：EP14781682.1
申请日：2014-09-12
发明人： ANDOH, Nobuharu , SANPEI, Osamu , TOGA, Tetsuo , MORRIS, David Lawson , ASTON, Roger , TANAKA, Koji , HINO, Tomokazu
IPC分类号： A61K31/277 , A61K31/341 , A61K31/381 , A61K31/415 , A61K31/4196 , A61K31/42 , A61K31/421 , A61K31/4245 , A61K31/426 , A61K31/433 , A61K31/437 , A61K31/44 , A61K31/4965 , A61K31/505 , A61K31/5377 , A61K31/5383 , A61P35/00
-
-
搜索结果
3 条记录 (耗时 0.018 秒)
