TISSUE FRAGMENT
    2.
    发明公开
    TISSUE FRAGMENT 审中-公开
    组织碎片

    公开(公告)号:EP3208328A1

    公开(公告)日:2017-08-23

    申请号:EP15850423.3

    申请日:2015-10-16

    申请人: Kyoto University

    摘要: Provided is a method for producing a tissue-like construct having cultured cells organized in an aligned manner, especially, a cardiac tissue-like construct. The tissue-like construct prepared by this method is also provided. Further provided are a device for evaluating cellular electrophysiological functions and a method for evaluating cellular electrophysiological functions. Furthermore, a sheet-like cell culture scaffold is also provided.

    摘要翻译: 本发明提供生产具有以排列方式组织化的培养细胞的组织样构建体的方法,特别是心脏组织样构建体。 还提供了通过该方法制备的组织样构建体。 进一步提供了用于评估细胞电生理功能的装置和用于评估细胞电生理功能的方法。 此外,还提供片状细胞培养支架。

    MICROFLUID DEVICE AND THREE-DIMENSIONAL MICROCULTURE METHOD FOR CELL
    4.
    发明公开
    MICROFLUID DEVICE AND THREE-DIMENSIONAL MICROCULTURE METHOD FOR CELL 审中-公开
    MIKROFLUIDISCHE VORRICHTUNG UND DREIDIMENSIONAL MIKROKULTURVERFAHRENFÜRZELLEN

    公开(公告)号:EP3112450A1

    公开(公告)日:2017-01-04

    申请号:EP15756050.9

    申请日:2015-02-24

    申请人: Kyoto University

    IPC分类号: C12M1/00 C12M3/00 C12N5/071

    摘要: The present invention provides a microfluidic device comprising at least one cell culture chamber, the or each chamber being connected to at least two openings, the device being configured to supply at least one physiologically active substance from at least one of the openings to the or each cell culture chamber in such a manner as to form a concentration gradient or concentration gradients in the or each chamber when cells and a hydrogel are introduced into the or each chamber to culture the cells in a 3D-gel medium.

    摘要翻译: 本发明提供了一种包括至少一个细胞培养室的微流体装置,所述或每个室连接至少两个开口,所述装置被配置为将至少一种生理活性物质从至少一个开口供应至或每个 细胞培养室以当将细胞和水凝胶引入或每个室中以在3D凝胶介质中培养细胞时在该室或每个室中形成浓度梯度或浓度梯度。