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公开(公告)号：EP3427949B1
公开(公告)日：2024-10-09
申请号：EP17181083.1
申请日：2017-07-12
CPC分类号： A61L27/20 , C08B37/0039 , C12N5/0062 , C08L5/12 , B33Y70/00 , C12N2533/7620130101
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公开(公告)号：EP4422700A1
公开(公告)日：2024-09-04
申请号：EP22888233.8
申请日：2022-10-28
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3.发明公开
公开(公告)号：EP4376612A2
公开(公告)日：2024-06-05
申请号：EP22761205.8
申请日：2022-08-05
申请人： Novochizol SA
IPC分类号： A01N25/04 , A61L27/48 , A61L27/52 , A61L27/56 , B33Y70/00 , C08B37/08 , C08J5/22 , C08J9/28 , C08L29/04 , C09K17/20 , C12N5/00
CPC分类号： C08B37/003 , C09K17/20 , A61L27/52 , A61L27/56 , B33Y70/00 , C08J9/28 , B09C1/08 , C12N5/0062 , C12N5/0068 , C12N2537/1020130101 , C12N2533/7220130101 , C12N2533/7820130101 , A61L2400/0620130101 , A61L27/26 , A61L27/38 , C08L5/08 , C08L1/12 , C09D105/08 , C08J9/0061 , C08J2205/0220130101 , C08J2207/1020130101 , C08J2301/1220130101 , C08J2405/0820130101 , C08J2329/0420130101 , C08J2205/04420130101 , C12N15/1013 , C08J3/075
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公开(公告)号：EP4374169A1
公开(公告)日：2024-05-29
申请号：EP22846693.4
申请日：2022-07-22
发明人： GOODARZI, Hani , YU, Johnny
CPC分类号： G16C20/30 , G16B20/00 , G01N33/5082 , G01N33/5023 , C12N5/0697 , C12N5/0062 , C12N2503/0220130101 , C12N2513/0020130101 , C12N2510/0420130101 , G16B25/10
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公开(公告)号：EP2949349B1
公开(公告)日：2018-10-31
申请号：EP13872797.9
申请日：2013-05-27
申请人： Nantong University
发明人： GU, Xiaosong , DING, Fei , GU, Yun , XUE, Chengbin , YANG, Yumin , WANG, Yongjun , GONG, Leilei
CPC分类号： A61L27/3675 , A61L27/18 , A61L27/20 , A61L27/227 , A61L27/24 , A61L27/3604 , A61L27/3633 , A61L27/3683 , A61L27/3687 , A61L27/3878 , A61L27/3895 , A61L2430/32 , C12N5/0062 , C12N2513/00 , C12N2525/00 , C12N2527/00
摘要： A tissue engineered nerve graft for repairing peripheral nerve injury consists of a nerve conduit and a extracellular matrix (ECM) that is secreted by autologous or allogeneic support cells and obtained by decellularization. A preparation method of the ECM-modified tissue engineered nerve grafts containing support cells, nerve conduit and constructing a ECM-modified tissue engineered nerve graft.
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公开(公告)号：EP2575913B1
公开(公告)日：2018-07-25
申请号：EP11726544.7
申请日：2011-05-25
CPC分类号： A61L27/50 , A61L27/24 , A61L27/3604 , A61L27/3633 , A61L27/3808 , A61L27/3826 , A61L2430/02 , A61L2430/06 , A61L2430/26 , A61L2430/28 , A61L2430/30 , A61L2430/32 , A61L2430/34 , C12M21/08 , C12M23/06 , C12M23/34 , C12M25/14 , C12N5/0062 , C12N2533/54
摘要： Described are methods, cell growth substrates, and devices that are useful in preparing cell-containing graft materials for administration to patients. Tubular passages can be defined in cell growth substrates to promote distribution of cells into the substrates. Also described are methods and devices for preparing cell-seeded graft compositions, methods and devices for preconditioning cell growth substrates prior to application of cells, and cell seeded grafts having novel substrates, and uses thereof.
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公开(公告)号：EP3332695A1
公开(公告)日：2018-06-13
申请号：EP16203153.8
申请日：2016-12-09
发明人： Serwane, Friedhelm , Spatz, Joachim
IPC分类号： A61B5/00 , C12N5/0793 , C12N5/079
CPC分类号： G01N33/4833 , A61B5/0071 , A61B5/4836 , C12N5/0062 , C12N5/062 , C12N5/0621 , C12N2506/45 , C12N2513/00 , C12N2527/00 , G01J1/0407 , G01J1/42 , G01N33/5058 , G01N33/5082
摘要： A measurement device 100 comprises neuronal, in particular retinal, tissue 110 grown from stem cells, the neuronal tissue 110 having a three-dimensional shape neuronal cells that change an electric potential in cells of the neuronal tissue 110 in response to influences that act on the neuronal cells, and a read-out device 130 that is configured to measure neuronal responses of the neuronal tissue 110 via changes in the electric potential generated by the neuronal cells.
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公开(公告)号：EP3325611A1
公开(公告)日：2018-05-30
申请号：EP16826915.7
申请日：2016-07-21
发明人： O'MAHONY, Aidan Patrick , UTAMA, Robert Hadinoto , FIFE, Christopher Michael , ATAPATTU, Lakmali , RIBEIRO, Julio Cesar Caldeira , KAVALLARIS, Maria , GOODING, John, Justin
CPC分类号： C12N5/0062 , A61L27/20 , A61L27/52 , A61L2300/62 , A61L2300/64 , B29C64/112 , B29C64/188 , B29C64/40 , B29K2005/00 , B29L2031/40 , B33Y10/00 , B33Y40/00 , B33Y70/00 , C12N5/0012 , C12N2503/02 , C12N2513/00 , G01N33/5082 , C08L5/04
摘要： A process for producing a 3D tissue culture model by (a) printing a drop of bio-ink to a substrate; (b) printing a drop en.) of activator to the drop of bio-ink to form a hydrogel droplet; (c) repeating steps (a) and (b) in any order to form a hydrogel mold adapted to receive a drop containing cells; (d) printing a drop containing cells to the hydrogel mold; and (e) repeating steps (a) and (b) in any order to form a 3D tissue culture model comprising the cells encapsulated in the hydrogel mold.
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公开(公告)号：EP3317394A1
公开(公告)日：2018-05-09
申请号：EP16751483.5
申请日：2016-07-01
申请人： Insphero AG
发明人： LICHTENBERG, Jan , MORITZ, Wolfgang , KELM, Jens
摘要： Disclosed are devices for propagating at least one microtissue, methods for manufacturing such devices, and the use us such devices, said devices comprise at least one well, wherein said at least one well comprises an open upper section comprising an open upper end and an open lower end, and a lower section comprising an open upper end and a bottom end, wherein the upper section and the lower section are in fluid communication, and wherein the bottom end of the lower section of at least one well of said plurality of wells is provided with a well bottom, said lower section of said at least one well has a smaller cross-sectional area than the open upper section of the same well.
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公开(公告)号：EP3296018A1
公开(公告)日：2018-03-21
申请号：EP16189510.7
申请日：2016-09-19
IPC分类号： B01L3/00 , C12N5/0735 , C12N5/0793 , C12N5/071 , G01N33/50
CPC分类号： C12N5/0062 , B01L3/5085 , C12N5/062 , C12N5/0631 , C12N5/068 , C12N2506/02 , C12N2531/00 , G01N33/5073 , G01N2500/10
摘要： The invention provides methods for producing arrays of organoids, the arrays thereof and uses of such arrays.
摘要翻译： 本发明提供了用于产生类器官阵列的方法，其阵列以及这种阵列的用途。
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