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公开(公告)号:EP2014304B1
公开(公告)日:2013-01-16
申请号:EP08014286.2
申请日:2003-10-24
申请人: Norgine BV
发明人: Barras, Norman c/o Norgine Limited , Cox, Ian David c/o Norgine Limited , Ungar, Alex , Halphen, Marc
IPC分类号: A61K47/10 , A61K47/22 , A61K47/02 , A61K31/765
CPC分类号: A61K9/009 , A61K9/0095 , A61K31/375 , A61K31/765 , A61K33/00 , A61K33/04 , A61K33/06 , A61K33/14 , A61K45/06 , Y10S514/892 , A61K2300/00
摘要: Disclosed are compositions comprising, per litre of aqueous solution, from 30 to 350 g polyethylene glycol, from 3 to 20g of an ascorbic acid component comprising a mixture of ascorbic acid and one or more salts of ascorbic acid, and optionally one or more electrolytes selected from sodium chloride, potassium chloride, sodium hydrogen carbonate and one or more alkali metal or alkaline earth metal sulfates. Solutions and kits containing said components are also disclosed.
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公开(公告)号:EP2314319B1
公开(公告)日:2019-05-08
申请号:EP10179628.2
申请日:2003-10-24
申请人: Norgine BV
发明人: Barras, Norman , Cox, Ian , Ungar, Alex , Halphen, Marc
IPC分类号: A61K47/10 , A61K47/22 , A61K47/02 , A61K31/765 , A61K31/375
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公开(公告)号:EP3777850A1
公开(公告)日:2021-02-17
申请号:EP20189946.5
申请日:2015-03-09
申请人: Norgine BV
发明人: Clayton, Lucy , Cockett, Alasdair , Christodoulou, Mark , Davidson, Ian , Farrag, Lynn , Halphen, Marc , Jones, Leighton , Petrossian, Vanik , Tisi, David , Stein, Peter , Ungar, Alex , Worthington, Jeffrey
IPC分类号: A61K31/375 , A61K47/10 , A61K9/00 , A61K31/765 , A61K33/04 , A61K33/14 , A61P1/10
摘要: The invention provides a method of cleansing the colon of a subject before a diagnostic, therapeutic or surgical procedure comprising:
- administering to the subject an effective amount of a first colon cleansing solution;
- administering to the subject an effective amount of a second colon cleansing solution,
the first and second colon cleansing solutions being as defined in the application;
whereby the first colon cleansing solution is taken over a time period t(dl) followed by optional additional clear fluid over a time period t(cfl), and then following a time interval t(dose interval), the second colon cleansing solution is taken over a time period t(d2) followed by optional additional clear fluid over a time period t(cf2), whereby the subject undergoes the surgical, therapeutic or diagnostic procedure at a time t 2 after the beginning of the colon cleansing method, and whereby the time interval after the completion of the second additional clear fluid and the start of the surgical, therapeutic or diagnostic procedure is t(procedure interval).-
公开(公告)号:EP2014304B9
公开(公告)日:2013-04-17
申请号:EP08014286.2
申请日:2003-10-24
申请人: Norgine BV
发明人: Barras, Norman c/o Norgine Limited , Cox, Ian David c/o Norgine Limited , Ungar, Alex , Halphen, Marc
IPC分类号: A61K47/10 , A61K47/22 , A61K47/02 , A61K31/765
CPC分类号: A61K9/009 , A61K9/0095 , A61K31/375 , A61K31/765 , A61K33/00 , A61K33/04 , A61K33/06 , A61K33/14 , A61K45/06 , Y10S514/892 , A61K2300/00
摘要: Disclosed are compositions comprising, per litre of aqueous solution, from 30 to 350 g polyethylene glycol, from 3 to 20g of an ascorbic acid component comprising a mixture of ascorbic acid and one or more salts of ascorbic acid, and optionally one or more electrolytes selected from sodium chloride, potassium chloride, sodium hydrogen carbonate and one or more alkali metal or alkaline earth metal sulfates. Solutions and kits containing said components are also disclosed.
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