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6 条记录 (耗时 0.011 秒)

    Compressed pharmaceutical compositions comprising PEG and electrolytes
    1.
    发明公开
    Compressed pharmaceutical compositions comprising PEG and electrolytes 有权
    PEG发射弹药ENTALTENE KOMPRIMIERTE ARZNEIMITTELZUSAMMENSETZUNGEN

    公开(公告)号：EP2263680A1

    公开(公告)日：2010-12-22

    申请号：EP10177007.1

    申请日：2005-04-25

    申请人： Norgine BV

    发明人： Barras, Norman ,  Cox, Ian

    IPC分类号： A61K31/765 ,  A61P1/10 ,  A61K9/20 ,  A61K33/14

    CPC分类号： A61K9/2022 ,  A61K9/0007 ,  A61K31/77

    摘要： The invention provides a compressed pharmaceutical composition comprising
    - polyethylene glycol of molecular weight from 2000 to 4500, wherein the polyethylene glycol makes up from 80 to 99.5% by weight of the composition, and
    - one or more electrolytes.
    The compressed pharmaceutical composition of the invention comprising polyethylene glycol has been found to have a more agreeable taste and a more agreeable mouthfeel than previously proposed liquid or dry powder or granular compositions.

    摘要翻译： 本发明提供一种包含分子量为2000至4500的聚乙二醇的压缩药物组合物，其中聚乙二醇占组合物重量的80-99.5％，和一种或多种电解质。 已经发现包含聚乙二醇的本发明的压缩药物组合物具有比先前提出的液体或干燥粉末或颗粒组合物更好的味道和更令人愉快的口感。

    COMPRESSED PHARMACEUTICAL COMPOSITIONS COMPRISING PEG AND ELECTROLYTES
    3.
    发明授权
    COMPRESSED PHARMACEUTICAL COMPOSITIONS COMPRISING PEG AND ELECTROLYTES 有权
    与PEG和电解质的压制药物组合物

    公开(公告)号：EP1742645B1

    公开(公告)日：2011-01-26

    申请号：EP05735983.8

    申请日：2005-04-25

    申请人： Norgine BV

    发明人： Barras, Norman ,  Cox, Ian

    IPC分类号： A61K31/765 ,  A61P1/10 ,  A61K9/20 ,  A61K33/14

    CPC分类号： A61K9/2022 ,  A61K9/0007 ,  A61K31/77

    摘要： The invention provides a compressed pharmaceutical composition comprising polyethylene glycol of molecular weight from 2000 to 4500, wherein the polyethylene glycol makes up from 80 to 99.5% by weight of the composition, one or more electrolytes for the treatment of constipation, faecal impaction, faecal retention, intestinal gas and cramping, or flatulence; or for orthostatic lavage, colon evacuation or colon cleansing. It has been found, surprisingly, that a compressed pharmaceutical composition comprising PEG for example a solid tablet, is significantly more palatable than previously proposed compositions and is effective when administered. The compressed pharmaceutical composition of the invention comprising polyethylene glycol has been found to have a more agreeable taste and a more agreeable mouthfeel than previously proposed liquid or dry powder or granular compositions.

    Laxative preparation containing l-Arginine
    5.
    发明公开
    Laxative preparation containing l-Arginine 审中-公开
    Abführzusammensetzung含L-精氨酸

    公开(公告)号：EP2022494A3

    公开(公告)日：2009-05-27

    申请号：EP08020742.6

    申请日：2000-10-18

    申请人： Norgine BV ,  President and Fellows of Harvard College

    发明人： Barras, Norman ,  Hechtman, Herbert, B.

    IPC分类号： A61K31/198 ,  A61P1/10 ,  A61K9/00

    CPC分类号： A61K31/198 ,  A61K9/0031

    摘要： The invention relates to L-arginine, a derivative thereof or a pharmaceutically acceptable salt thereof for use as a laxative, for treatment of constipation and for clearing the rectum and/or the colon of a mammal. Compositions suitable for topical administration to an area of the gastrointestinal tract are provided. Orally administered preparations comprising for example an enteric coating that dissolves at a desired location in the gastrointestinal tract; a controlled release formulation; a sustained release formulation; a targeted drug delivery system; or a combination thereof are also provided.

    Laxative preparation containing l-Arginine
    6.
    发明公开
    Laxative preparation containing l-Arginine 审中-公开
    含有L-精氨酸的泻药制剂

    公开(公告)号：EP2022494A2

    公开(公告)日：2009-02-11

    申请号：EP08020742.6

    申请日：2000-10-18

    申请人： Norgine BV ,  President and Fellows of Harvard College

    发明人： Barras, Norman ,  Hechtman, Herbert, B.

    IPC分类号： A61K31/198 ,  A61P1/10

    CPC分类号： A61K31/198 ,  A61K9/0031

    摘要： The invention relates to L-arginine, a derivative thereof or a pharmaceutically acceptable salt thereof for use as a laxative, for treatment of constipation and for clearing the rectum and/or the colon of a mammal. Compositions suitable for topical administration to an area of the gastrointestinal tract are provided. Orally administered preparations comprising for example an enteric coating that dissolves at a desired location in the gastrointestinal tract; a controlled release formulation; a sustained release formulation; a targeted drug delivery system; or a combination thereof are also provided.

    摘要翻译： 本发明涉及L-精氨酸，其衍生物或其药学上可接受的盐用作缓泻剂，用于治疗便秘和清除哺乳动物的直肠和/或结肠。 提供了适用于局部施用于胃肠道区域的组合物。 口服给药制剂，其包含例如在胃肠道中的期望位置溶解的肠溶包衣; 控释制剂; 缓释制剂; 有针对性的药物输送系统; 或者它们的组合。