公开(公告)号：EP2491029B1

公开(公告)日：2016-02-10

申请号：EP10768927.5

申请日：2010-10-19

申请人： Novartis AG

发明人： BEBERNITZ, Gregory, Raymond ,  BOCK, Mark, G. ,  REDDY, Dumbala Srinivas ,  HAJARE, Atul Kashinath ,  VYAVAHARE, Vinod ,  BHOSALE, Sandeep Bhausaheb ,  KURHADE, Suresh Eknath ,  SALUNKHE, Videsh ,  SHAIKH, Nadim, S. ,  BHUNIYA, Debnath ,  PALLE, P., Venkata ,  FENG, Lili ,  LIANG, Jessica

IPC分类号： C07D405/10 ,  C07D407/10 ,  C07D413/10 ,  A61K31/70 ,  A61P3/10

CPC分类号： A61K31/7052 ,  A61K31/7048 ,  A61K31/706 ,  C07D405/10 ,  C07D407/10 ,  C07D413/10 ,  C07H7/04

摘要： This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.

摘要翻译： 本发明涉及由式（I）表示的化合物：其中变量如上文所定义，其可用于治疗D-葡萄糖共转运蛋白（SGLT）介导的疾病和病症，例如， 糖尿病。 本发明还提供了治疗这些疾病和病症以及组合物等的治疗方法。

公开(公告)号：EP2491029A1

公开(公告)日：2012-08-29

申请号：EP10768927.5

申请日：2010-10-19

申请人： Novartis AG

发明人： BEBERNITZ, Gregory, Raymond ,  BOCK, Mark, G. ,  REDDY, Dumbala Srinivas ,  HAJARE, Atul Kashinath ,  VYAVAHARE, Vinod ,  BHOSALE, Sandeep Bhausaheb ,  KURHADE, Suresh Eknath ,  SALUNKHE, Videsh ,  SHAIKH, Nadim, S. ,  BHUNIYA, Debnath ,  PALLE, P., Venkata ,  FENG, Lili ,  LIANG, Jessica

IPC分类号： C07D405/10 ,  C07D407/10 ,  C07D413/10 ,  A61K31/70 ,  A61P3/10

CPC分类号： A61K31/7052 ,  A61K31/7048 ,  A61K31/706 ,  C07D405/10 ,  C07D407/10 ,  C07D413/10 ,  C07H7/04

摘要： This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.