专利检索 ap:("Novartis AG") AND inv:"COBB, Jennifer" 第 1 页

1.

发明授权
LYSINE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS USING MICROBIAL TRANSGLUTAMINASE 有权

公开(公告)号：EP3019515B1

公开(公告)日：2019-08-21

申请号：EP14748350.7

申请日：2014-07-11

申请人： Novartis AG

发明人： USERA, Aimee , ROBINSON, Zachary , COBB, Jennifer

IPC分类号： C07K1/13 , C07H13/00 , C07C317/24 , C07C237/06 , C07C247/04 , C07D209/42 , C07C13/45 , C07K5/083 , C07K5/072 , C07K5/062 , C07K7/02 , C07C271/22 , C07D229/02 , C07D257/08 , A61K47/64

2.

发明公开
LYSINE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS USING MICROBIAL TRANSGLUTAMINASE 审中-公开

公开(公告)号：EP3613755A1

公开(公告)日：2020-02-26

申请号：EP19187438.7

申请日：2014-07-11

申请人： Novartis AG

发明人： USERA, Aimee , ROBINSON, Zachary , COBB, Jennifer

IPC分类号： C07K1/107 , A61K47/64 , A61K38/00 , C07C271/22

摘要： The present invention relates to methods and reagents for use in site-selective modification of proteins having lysine residues with functionalized peptides using a chemoenzymatic microbial transglutaminase-mediated reaction. The functionalized proteins may be used for study or therapeutic uses.