Ocular devices with functionalized surface with adhesive properties
    5.
    发明公开
    Ocular devices with functionalized surface with adhesive properties 审中-公开
    具有粘着性的功能化表面的视觉装置

    公开(公告)号:EP1364663A1

    公开(公告)日:2003-11-26

    申请号:EP02011173.8

    申请日:2002-05-21

    IPC分类号: A61L27/18 A61L27/34

    摘要: The present invention relates to biomedical devices, in particular ocular devices, comprising:

    a bulk material resulting from the co-polymerization of funtionalized perfluoroalkylpolyether (PFPE) macromonomers and zwitterionic substituted ethylenic units
    a surface activated with a glycoprotein or collagen
    said surface being coated with a functionalized polyethylene glycol (PEG).
    The coating allows for adhering or crosslinking to tissues, so that said devices may be used, e.g., as ready-to-use corneal onlays in ophthalmic surgery.

    摘要翻译: 本发明涉及一种生物医学器件,特别是视觉装置,其包括:散装材料从共聚合的官能化的全氟烷基聚醚(PFPE)大单体和两性离子substituiertem烯单位的糖蛋白或胶原蛋白激活的表面所得到的所述被涂布表面 官能化的聚乙二醇(PEG)。 该涂层允许用于粘附或交联的组织,所以可以使用这就是说设备,E. G.,在眼科手术为准备使用的角膜覆盖物。

    VERFAHREN ZUR HERSTELLUNG WÄSSRIGER STRAHLENHÄRTBARER LACKE
    7.
    发明授权
    VERFAHREN ZUR HERSTELLUNG WÄSSRIGER STRAHLENHÄRTBARER LACKE 失效
    用于生产水性可辐射涂料

    公开(公告)号:EP0865471B1

    公开(公告)日:2000-06-28

    申请号:EP96939837.9

    申请日:1996-11-18

    IPC分类号: C09D167/06

    摘要: The invention relates to methods of producing aqueous radiation-hardened paints from water-incompatible radiation-hardened initial paints (A) containing the following: (a) 40-100 wt.% at least one oligomeric and/or polymeric water-incompatible binder with at least two ethylenically unsaturated double bonds per molecule; (b) 0-40 wt.% fillers and/or pigments; (c) 0-6 wt.% photoinitiators; and (d) 0-20 wt.% further auxiliary agents and/or additives. The proposed methods are characterised in that they involve the following consecutive process steps: 1) the water-incompatible initial paint (A) is mixed with a quantity of a di- or polyamine (B) with at least one primary and at least one tertiary amino group equivalent to 0.2-5 wt.% of the quantity of (A); 2) the amino groups of component (B) are neutralised with an acid; and 3) the water-soluble paint produced in stages 1) and 2) is converted to the aqueous phase and the application viscosity is set to the required level by adding water.