专利检索 ap:("Novartis AG" OR "Intellia Therapeutics, Inc.") AND inv:"COOKE, Michael" 第 1 页

1.

发明公开
COMPOSITIONS AND METHODS FOR THE TREATMENT OF HEMOGLOBINOPATHIES 审中-公开

公开(公告)号：EP4053277A1

公开(公告)日：2022-09-07

申请号：EP21213766.5

申请日：2016-12-26

申请人： Novartis AG , Intellia Therapeutics, Inc.

发明人： BOITANO, Anthony Edward , COOKE, Michael , KLICKSTEIN, Lloyd B. , LESCARBEAU, Reynald , MICKANIN, Craig Stephen , MULUMBA, Kabungo , POLICE, Seshidhar Reddy , SNEAD, Jennifer , STEVENSON, Susan C. , STEWART, Morag , YANG, Yi

IPC分类号： C12N15/113

摘要： The present invention is directed to genome editing systems, reagents and methods for the treatment of hemoglobinopathies.

2.

发明授权
COMPOSITIONS AND METHODS FOR ENHANCED GENERATION OF HEMATOPOIETIC STEM/PROGENITOR CELLS 有权

公开(公告)号：EP2788476B1

公开(公告)日：2019-05-22

申请号：EP12806795.6

申请日：2012-12-07

申请人： Fred Hutchinson Cancer Research Center , Novartis AG

发明人： BERNSTEIN, Irwin, D. , BOITANO, Anthony, E. , COOKE, Michael , DELANEY, Colleen

IPC分类号： C12N5/0789 , A61K35/12

3.

发明授权
COMPOUNDS THAT EXPAND HEMATOPOIETIC STEM CELLS 有权

公开(公告)号：EP2350078B1

公开(公告)日：2019-04-17

申请号：EP09748626.0

申请日：2009-10-29

申请人： Novartis AG , The Scripps Research Institute

发明人： BOITANO, Anthony , COOKE, Michael , PAN, Shifeng , SCHULTZ, Peter G. , TELLEW, John , WAN, Yongqin , WANG, Xing

IPC分类号： C07D473/34 , C07D487/04 , A61K31/52 , A61K31/519 , A61P37/00

4.

发明公开
COMPOSITIONS COMPRISING NAPHTHYRIDINE DERIVATIVES AND ALUMINIUM ADJUVANT FOR USE IN TREATING SOLID TUMORS 审中-公开

公开(公告)号：EP3624806A1

公开(公告)日：2020-03-25

申请号：EP18730857.2

申请日：2018-05-17

申请人： Novartis AG

发明人： COOKE, Michael , KASIBHATLA, Shailaja , MILLER, Andrew T. , WU, Tom Yao-Hsiang

IPC分类号： A61K31/675 , A61P35/00 , A61K39/00 , A61K9/19 , A61K45/06

5.

发明公开
EXPANDED HEMATOPOIETIC STEM CELLS FROM CORD BLOOD AND THEIR THERAPEUTIC USE 审中-公开

公开(公告)号：EP3524604A1

公开(公告)日：2019-08-14

申请号：EP19164770.0

申请日：2009-10-29

申请人： Novartis AG , The Scripps Research Institute

发明人： BOITANO, Anthony , COOKE, Michael , PAN, Shifeng , SCHULTZ, Peter G. , TELLEW, John , WAN, Yongqin , WANG, Xing

IPC分类号： C07D473/34 , C07D487/04 , A61K35/28 , C12N5/0789 , A61P7/00 , A61P43/00 , A61P35/00 , A61K31/52 , A61K31/519 , A61P37/00

摘要： The present invention relates to compounds and compositions for expanding the number of CD34+ cells for transplantation. The invention further relates to a cell population comprising expanded hematopoietic stem cells (HSCs) and its use in autologous or allogeneic transplantation for the treatment of patients with inherited immunodeficient and autoimmune diseases and diverse hematopoietic disorders to reconstitute the hematopoietic cell lineages and immune system defense.