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公开(公告)号：EP1795604A4
公开(公告)日：2008-08-27
申请号：EP05790164
申请日：2005-09-28
IPC分类号： A61K49/00 , A61K35/76 , C07K14/47 , C07K14/705 , G01N33/576
CPC分类号： C12N15/86 , A61K49/0047 , C07K14/4702 , C07K14/70575 , C12N7/00 , C12N2710/10343 , C12N2830/008 , C12N2840/203 , G01N33/574
摘要： It is intended to provide a regent for detecting cancer cells or diagnosing cancer. More specifically speaking, a reagent for detecting cancer cells containing a recombinant virus in which a replication cassette having a human telomerase promoter, E1A gene, IRES sequence and E1B gene in this order is integrated into the E1 region of the virus genome while a labeling cassette having a gene encoding a labeled protein and a promoter capable of regulating the expression of the gene is integrated into the E3 region of the virus genome.
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公开(公告)号：EP1859804A4
公开(公告)日：2010-09-01
申请号：EP06713930
申请日：2006-02-10
发明人： FUJIWARA TOSHIYOSHI , TANAKA NORIAKI , KYO SATORU
IPC分类号： A61K35/76 , A61K31/337 , A61K31/4745 , A61K31/475 , A61K38/00 , A61K45/00 , A61K48/00 , A61P35/00 , A61P35/02 , A61P43/00
CPC分类号： A61K31/475 , A61K31/337 , A61K31/4745 , A61K35/761 , A61K38/1758 , A61K45/06 , A61K48/00 , A61K2300/00
摘要： The present invention relates to providing a pharmaceutical composition with a still more enhanced anticancer activity. Specifically, the present invention relates to a pharmaceutical composition for combination therapy for tumors, comprising a recombinant virus comprising a polynucleotide containing a promoter for human telomerase, an E1A gene, an IRES sequence and an E1B gene in this order, and a substance having an antitumor effect.
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