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公开(公告)号：EP3960758A1
公开(公告)日：2022-03-02
申请号：EP20795091.6
申请日：2020-04-15
Inventor： UEDA, Koji , OHNISHI, Naomi , TSUJIKAWA, Kazutake , NONOMURA, Norio , UEMURA, Motohide , JINGUSHI, Kentaro , OHTAKE, Norihisa , KAWAI, Yasutoshi
IPC: C07K14/47 , C07K16/32 , G01N33/574 , G01N33/68
Abstract: An object of the invention is to provide a method for detecting cancer in a simple and highly accurate manner, and a reagent that can be used in the method. A method for detecting cancer (excluding renal cell cancer), which comprises measuring the level of Azurocidin (AZU1) in a sample, in which it is determined that cancer is detected when a measured value exceeds a preset reference value. The cancer is preferably selected from the group consisting of stomach cancer, breast cancer, colorectal cancer, and lung cancer. A reagent containing an antibody that specifically recognizes AZU1 is used in detecting cancer (excluding renal cell cancer).
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公开(公告)号：EP3858860A1
公开(公告)日：2021-08-04
申请号：EP20216033.9
申请日：2018-03-28
Applicant: Shionogi & Co., Ltd , Osaka University
Inventor： YOSHIDA, Tetsuya , KIDANI, Yujiro , MATSUMOTO, Mitsunobu , KANAZAWA, Takayuki , SHINONOME, Satomi , HOJO, Kanji , OHKURA, Naganari , SAKAGUCHI, Shimon , TANAKA, Atsushi , WADA, Hisashi , KAWASHIMA, Atsunari , NONOMURA, Norio
IPC: C07K16/28 , A61K39/395 , A61P35/00
Abstract: The present invention provides a pharmaceutical composition for cancer treatment comprising an antibody against CCR8.
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公开(公告)号：EP4495059A3
公开(公告)日：2025-03-26
申请号：EP24218136.0
申请日：2018-07-04
Applicant: OSAKA UNIVERSITY
Inventor： KOBAYASHI, Hikaru , KOBAYASHI, Yuki , IMAMURA, Ryoichi , NONOMURA, Norio
Abstract: One drug (solid preparation) 100 of the present invention is a drug for a disease of kidney that contains a silicon fine particle, an aggregate of the silicon fine particles, or a crystal grain of silicon having a hydrogen-generating ability. Hydrogen generated from the silicon fine particle in the drug can contribute to the prevention and/or treatment of the kidney disease.
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Patent Agency Ranking
公开(公告)号：EP4063845A1
公开(公告)日：2022-09-28
申请号：EP20890874.9
申请日：2020-11-13
Applicant: OSAKA UNIVERSITY , Tosoh Corporation
Inventor： UEMURA, Motohide , NONOMURA, Norio , UJIKE Takeshi , MYOBA, Shohei , OHTAKE, Norihisa
IPC: G01N27/62 , G01N33/53 , G01N33/574 , G01N33/68
Abstract: A problem to be addressed by the present invention is to provide: a method for detecting bone metastasis of cancer (excluding castration resistant prostate cancer) in a simple and highly accurate manner; and a reagent that can be used in the method. Bone metastasis of cancer (excluding castration resistant prostate cancer) is detected by measuring an intact growth and differentiation factor 15 (GDF15) propeptide level, a GDF15 propeptide fragment level, and the total of an intact GDF15 propeptide level and a GDF15 propeptide fragment level in a sample. The above described method for detecting bone metastasis of cancer includes a method for detecting bone metastasis of prostate cancer other than castration resistant prostate cancer, renal cancer, lung cancer, breast cancer, thyroid cancer, pancreatic cancer, bladder cancer, colon cancer, melanoma, myeloma, or lymphoma. Further, the reagent for detecting bone metastasis of cancer (excluding castration resistant prostate cancer) includes an antibody that specifically recognizes GDF15 propeptide.
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公开(公告)号：EP4495059A2
公开(公告)日：2025-01-22
申请号：EP24218136.0
申请日：2018-07-04
Applicant: OSAKA UNIVERSITY
Inventor： KOBAYASHI, Hikaru , KOBAYASHI, Yuki , IMAMURA, Ryoichi , NONOMURA, Norio
IPC: C01B3/06
Abstract: One drug (solid preparation) 100 of the present invention is a drug for a disease of kidney that contains a silicon fine particle, an aggregate of the silicon fine particles, or a crystal grain of silicon having a hydrogen-generating ability. Hydrogen generated from the silicon fine particle in the drug can contribute to the prevention and/or treatment of the kidney disease.
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公开(公告)号：EP4258001A1
公开(公告)日：2023-10-11
申请号：EP21900657.4
申请日：2021-11-25
Applicant: OSAKA UNIVERSITY
Inventor： KIOKA, Hidetaka , TAKAHASHI, Yusuke , FUKUHARA, Shinichiro , SAKATA, Yasushi , NONOMURA, Norio , TAKASHIMA, Seiji , SAITO, Shigeyoshi
IPC: G01R33/46 , G01R33/485 , G01N24/08 , A61B5/055
Abstract: An evaluation method is performed by an arithmetic circuit and includes obtainment processing (S 1), evaluation processing (S2), and presentation processing (S3). The obtainment processing (S 1) obtains: image information on a sectional image representing an interested section of an organism including a target section of a testis of the organism generated by use of magnetic resonance of hydrogen atoms; and concentration information on a creatine concentration in the interested section measured by use of magnetic resonance based on chemical exchange saturation transfer. The evaluation processing (S2) generates an evaluation image representing a distribution of evaluation results of a testicular function in the target section based on the concentration information. The presentation processing (S3) presents the sectional image and the evaluation image.
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公开(公告)号：EP3616720A1
公开(公告)日：2020-03-04
申请号：EP19202367.9
申请日：2018-03-28
Applicant: Shionogi & Co., Ltd , Osaka University
Inventor： YOSHIDA, Tetsuya , KIDANI, Yujiro , MATSUMOTO, Mitsunobu , KANAZAWA, Takayuki , SHINONOME, Satomi , HOJO, Kanji , OHKURA, Naganari , SAKAGUCHI, Shimon , TANAKA, Atsushi , WADA, Hisashi , KAWASHIMA, Atsunari , NONOMURA, Norio
IPC: A61K39/395 , A61P35/00 , C07K16/28
Abstract: The present invention provides a pharmaceutical composition for cancer treatment comprising an antibody against CCR8.
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公开(公告)号：EP3431105B1
公开(公告)日：2020-01-01
申请号：EP18775737.2
申请日：2018-03-28
Applicant: Shionogi & Co., Ltd. , Osaka University
Inventor： YOSHIDA, Tetsuya , KIDANI, Yujiro , MATSUMOTO, Mitsunobu , KANAZAWA, Takayuki , SHINONOME, Satomi , HOJO, Kanji , OHKURA, Naganari , SAKAGUCHI, Shimon , TANAKA, Atsushi , WADA, Hisashi , KAWASHIMA, Atsunari , NONOMURA, Norio
IPC: A61K39/395 , A61P35/00 , C07K16/28
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