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公开(公告)号:EP3515489A1
公开(公告)日:2019-07-31
申请号:EP17851784.3
申请日:2017-09-19
发明人: LIU, Yang , DEVENPORT, Martin , ZHENG, Pan , WU, Wei , DU, Xuexiang , LIU, Mingyue , TANG, Fei
IPC分类号: A61K39/395 , A61K39/00 , A61K38/00 , C07K14/00
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公开(公告)号:EP3921339A2
公开(公告)日:2021-12-15
申请号:EP20753142.7
申请日:2020-02-05
发明人: LIU, Yang , ZHENG, Pan , WANG, Xu , DEVENPORT, Martin
IPC分类号: C07K14/705 , A61K39/00 , A61K38/00 , G01N33/53 , G01N33/00
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公开(公告)号:EP3813877A1
公开(公告)日:2021-05-05
申请号:EP19803135.3
申请日:2019-05-13
发明人: LIU, Yang , ZHENG, Pan , FLORES, Rhonda , CHOU, Hung-Yen , XUE, Zhihong , YE, Peiying , DEVENPORT, Martin
IPC分类号: A61K39/395
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公开(公告)号:EP3373910A1
公开(公告)日:2018-09-19
申请号:EP16864923.4
申请日:2016-11-09
发明人: LIU, Yang , WANG, Yin , LIU, Yan , BAILEY, Christopher , ZHENG, Pan
IPC分类号: A61K9/127 , A61K31/395 , A61K35/74 , A61K38/08 , A61K38/12
CPC分类号: A61K9/1271 , A61K9/1277 , A61K35/74 , A61K38/164 , A61K47/6911 , A61P35/02 , A61P37/02
摘要: A liposomal drug formulation for treating a disease in a patient characterized by overexpression of HIF-1α and/or HIF-2α includes a plurality of liposomes in a pharmaceutically acceptable carrier. The liposomes encapsulate echinomycin and are made from a peglyated phospholipid, a neutral phosphoglyceride, and a sterol. The PEGylated liposomes may be used to treat proliferative diseases, leukemia, cancer, autoimmune diseases and graft-versus-host disease.
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公开(公告)号:EP2563385B1
公开(公告)日:2017-08-02
申请号:EP11778000.7
申请日:2011-04-28
申请人: Oncoimmune Inc.
发明人: ZHENG, Xincheng , WU, Wei , LIU, Yang , ZHENG, Pan
IPC分类号: A61K38/17 , A61P19/02 , C07K14/705
CPC分类号: C07K14/70596 , A61K38/177 , A61K2039/505 , C07K16/18 , C07K2319/30
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6.
公开(公告)号:EP3921338A1
公开(公告)日:2021-12-15
申请号:EP20752440.6
申请日:2020-02-05
发明人: LIU, Yang , ZHENG, Pan , WANG, Xu , LIU, Mingyue , DEVENPORT, Martin
IPC分类号: C07K14/705 , C07K14/435 , C07K19/00
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公开(公告)号:EP3389699A1
公开(公告)日:2018-10-24
申请号:EP16876612.9
申请日:2016-12-14
申请人: Oncoimmune, Inc.
发明人: LIU, Yang , ZHENG, Pan , DEVENPORT, Martin
IPC分类号: A61K39/00 , A61K39/395 , C12P21/08 , C07K16/00
CPC分类号: A61K39/00 , A61K2039/505 , A61K2039/507 , C07K16/2818 , C07K16/2878 , C07K2317/24 , C07K2317/34 , C07K2317/52 , C07K2317/72 , C07K2317/732 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要: This invention relates to compositions of chimeric and humanized antibodies that bind to the human CTLA4 molecule and their use in cancer immunotherapy and for reduction of autoimmune side effects compared to other immunotherapeutic agents.
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8.
公开(公告)号:EP3292144A1
公开(公告)日:2018-03-14
申请号:EP16790128.9
申请日:2016-05-06
申请人: Oncoimmune, Inc.
发明人: LIU, Yang , ZHENG, Pan
IPC分类号: C07K14/705 , C12Q1/60 , G01N33/92
摘要: The present invention relates to the use of a CD24 protein for lowering low-density lipoprotein cholesterol levels, treating and preventing atherosclerosis, and for reducing risk of cardiovascular disease.
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公开(公告)号:EP4103218A1
公开(公告)日:2022-12-21
申请号:EP21754198.6
申请日:2021-02-10
申请人: Oncoimmune Inc.
发明人: LIU, Yang , ZHENG, Pan , DEVENPORT, Martin , LI, Dongling , MU, Libing , FANG, Xianfeng
IPC分类号: A61K38/17 , A61K39/00 , C07K14/705 , A61P31/14 , A61P11/00
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公开(公告)号:EP4103217A1
公开(公告)日:2022-12-21
申请号:EP21753162.3
申请日:2021-02-10
发明人: LIU, Yang , ZHENG, Pan , DEVENPORT, Martin , TIAN, Renrong , ZHENG, Yongtang
IPC分类号: A61K38/17 , C07K14/705
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