公开(公告)号：EP2834233B1

公开(公告)日：2018-04-25

申请号：EP13719297.7

申请日：2013-03-28

申请人： ORION CORPORATION

发明人： KOSKELAINEN, Tuula ,  LINNANEN, Tero ,  MINKKILÄ, Anna ,  MÄKELÄ, Mikko ,  POHJAKALLIO, Antti

IPC分类号： C07D405/04 ,  C07D409/04 ,  A61K31/4178 ,  A61P25/00 ,  A61P9/00

CPC分类号： C07D409/04 ,  A61K31/4178 ,  C07D233/04 ,  C07D405/04 ,  C07D405/14

摘要： Compounds of formula (I), wherein X and R1-R6, are as defined in the claims, exhibit alpha2 agonistic activity and thus are useful as alpha2 agonists, especially as alpha2A agonists. Methods of use of said compounds are also provided.

公开(公告)号：EP2834233A1

公开(公告)日：2015-02-11

申请号：EP13719297.7

申请日：2013-03-28

申请人： Orion Corporation

发明人： KOSKELAINEN, Tuula ,  LINNANEN, Tero ,  MINKKILÄ, Anna ,  MÄKELÄ, Mikko ,  POHJAKALLIO, Antti

IPC分类号： C07D405/04 ,  C07D409/04 ,  A61K31/4178 ,  A61P25/00 ,  A61P9/00

CPC分类号： C07D409/04 ,  A61K31/4178 ,  C07D233/04 ,  C07D405/04 ,  C07D405/14

摘要： Compounds of formula (I), wherein X and R1-R6, are as defined in the claims, exhibit alpha2 agonistic activity and thus are useful as alpha2 agonists, especially as alpha2A agonists. Methods of use of said compounds are also provided.