专利检索 ap:("Orion Corporation") AND inv:"POHJAKALLIO, Antti" 第 1 页

1.

发明授权
NEW ALPHA2 ADRENOCEPTOR AGONISTS 有权
标题翻译：新的ALPHA2 ADRENOCEPTOR AGONISTS

公开(公告)号：EP2834233B1

公开(公告)日：2018-04-25

申请号：EP13719297.7

申请日：2013-03-28

申请人： ORION CORPORATION

发明人： KOSKELAINEN, Tuula , LINNANEN, Tero , MINKKILÄ, Anna , MÄKELÄ, Mikko , POHJAKALLIO, Antti

IPC分类号： C07D405/04 , C07D409/04 , A61K31/4178 , A61P25/00 , A61P9/00

CPC分类号： C07D409/04 , A61K31/4178 , C07D233/04 , C07D405/04 , C07D405/14

摘要： Compounds of formula (I), wherein X and R1-R6, are as defined in the claims, exhibit alpha2 agonistic activity and thus are useful as alpha2 agonists, especially as alpha2A agonists. Methods of use of said compounds are also provided.

2.

发明公开
NEW ALPHA2 ADRENOCEPTOR AGONISTS 有权
标题翻译：全新的α-2-肾上腺素受体激动剂

公开(公告)号：EP2834233A1

公开(公告)日：2015-02-11

申请号：EP13719297.7

申请日：2013-03-28

申请人： Orion Corporation

发明人： KOSKELAINEN, Tuula , LINNANEN, Tero , MINKKILÄ, Anna , MÄKELÄ, Mikko , POHJAKALLIO, Antti

IPC分类号： C07D405/04 , C07D409/04 , A61K31/4178 , A61P25/00 , A61P9/00

CPC分类号： C07D409/04 , A61K31/4178 , C07D233/04 , C07D405/04 , C07D405/14

摘要： Compounds of formula (I), wherein X and R1-R6, are as defined in the claims, exhibit alpha2 agonistic activity and thus are useful as alpha2 agonists, especially as alpha2A agonists. Methods of use of said compounds are also provided.

3.

发明授权
2-(1-HETEROARYLPIPERAZIN-4-YL)METHYL-1,4-BENZODIOXANE DERIVATIVES AS ALPHA2C ANTAGONISTS 有权

公开(公告)号：EP3303327B1

公开(公告)日：2020-03-11

申请号：EP16729605.2

申请日：2016-06-03

申请人： Orion Corporation

发明人： WANG, Shouming , KUMPULAINEN, Esa , PYSTYNEN, Jarmo , POHJAKALLIO, Antti , HAIKARAINEN, Anssi

IPC分类号： C07D405/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D405/12 , C07D417/14 , C07D513/04 , A61K31/4155 , A61P25/00

4.

发明公开
BENZODIOXANE DERIVATIVES AND THEIR PHARMACEUTICAL USE 审中-公开

公开(公告)号：EP3478676A1

公开(公告)日：2019-05-08

申请号：EP17746151.4

申请日：2017-06-28

申请人： Orion Corporation

发明人： HAIKARAINEN, Anssi , KUMPULAINEN, Esa , POHJAKALLIO, Antti , PYSTYNEN, Jarmo , WANG, Shouming

IPC分类号： C07D405/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D473/00 , C07D487/04 , C07D487/10 , C07D513/04 , A61K31/453 , A61K31/519 , A61K31/52 , A61P25/28

5.

发明公开
2-(1-HETEROARYLPIPERAZIN-4-YL)METHYL-1,4-BENZODIOXANE DERIVATIVES AS ALPHA2C ANTAGONISTS 审中-公开
标题翻译：作为ALPHA2拮抗剂的2-（1-杂芳基哌嗪-4-基）甲基-1,4-苯并二恶烷衍生物

公开(公告)号：EP3303327A1

公开(公告)日：2018-04-11

申请号：EP16729605.2

申请日：2016-06-03

申请人： Orion Corporation

发明人： WANG, Shouming , KUMPULAINEN, Esa , PYSTYNEN, Jarmo , POHJAKALLIO, Antti , HAIKARAINEN, Anssi

IPC分类号： C07D405/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D405/12 , C07D417/14 , C07D513/04 , A61K31/4155 , A61P25/00

摘要： wherein A is an optionally substituted five-membered unsaturated heterocyclic ring containing 1, 2, or 3 N, O, or S ring heteroatom(s) exhibit alpha2C antagonistic activity and are thus useful for the treatment of diseases or conditions of the peripheric or central nervous system.