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    Rotable disk-shaped fluid sample collection device
    2.
    发明授权
    Rotable disk-shaped fluid sample collection device 有权
    可旋转的盘状流体样本收集装置

    公开(公告)号：EP2778679B1

    公开(公告)日：2017-09-27

    申请号：EP14159217.0

    申请日：2014-03-12

    申请人： Ortho-Clinical Diagnostics, Inc.

    发明人： Gunnerson, Kory A. ,  Jakubowicz, Raymond F. ,  Kirsch, Andrew M. ,  Robinson, James Ellis ,  Salotto, Daniel P. ,  Tomasso, David A. ,  Ding, Zhong ,  Gottermeier, William Franklin ,  Swick, Aaron Michael

    IPC分类号： G01N33/49 ,  B01L3/00 ,  G01N33/558

    CPC分类号： A61B5/150343 ,  A61B5/14507 ,  A61B5/1468 ,  A61B5/150213 ,  A61B5/157 ,  A61B10/007 ,  B01L3/502 ,  B01L2200/025 ,  B01L2200/0684 ,  B01L2300/0681 ,  B01L2300/087 ,  B01L2300/161 ,  B01L2400/0406 ,  B01L2400/0487 ,  B01L2400/0644 ,  G01N33/49

    摘要： A sample collection device (10) for a fluid, such as body fluids like blood, urine or saliva, includes: a substantially disk-shaped body having a periphery; a capillary channel (11) extending through the body and bounded by the periphery, having a first end (12) and a second end (13), wherein the first end (12) is adapted to draw the fluid into the channel (11) by capillary action; a sample collection well (14) located in the vicinity of the second end (13) and in fluid communication with the capillary channel (11); and an axis of rotation extending through the center of the disk and which is substantially perpendicular to the upper surface of the disk-shaped body. In a preferred embodiment, the sample collection device is adapted to rotate about the axis of rotation within a cartridge of a fluid measuring device, such as a lateral flow assay, wherein the cartridge has a housing comprising an air vent (32) in fluid communication with the capillary channel (11) when the disk is rotated in a first position.

    摘要翻译： 用于诸如血液，尿液或唾液之类的体液的流体的样本采集装置（10）包括：具有外围的基本上盘状的主体; （12）和第二端（13），其中所述第一端（12）适于将流体吸入所述通道（11）中，所述毛细管通道（11）延伸穿过所述主体并且由所述外围界定， 通过毛细管作用; 位于所述第二端（13）附近并与所述毛细管通道（11）流体连通的样品收集井（14）; 以及延伸穿过盘片中心的旋转轴线，该旋转轴线基本上垂直于盘形主体的上表面。 在一个优选实施例中，样品收集装置适于围绕流体测量装置的筒内的旋转轴线旋转，例如横向流动测定，其中筒具有包括流体连通的通气孔（32） 当盘在第一位置旋转时与毛细管通道（11）连通。

    Rotable disk-shaped fluid sample collection device
    3.
    发明公开
    Rotable disk-shaped fluid sample collection device 有权
    DrehbarescheibenförmigeFlüssigkeitsprobenentnahmevorrichtung

    公开(公告)号：EP2778679A1

    公开(公告)日：2014-09-17

    申请号：EP14159217.0

    申请日：2014-03-12

    申请人： Ortho-Clinical Diagnostics Inc

    发明人： Gunnerson, Kory A. ,  Jakubowicz, Raymond F. ,  Kirsch, Andrew M. ,  Robinson, James Ellis ,  Salotto, Daniel P. ,  Tomasso, David A. ,  Ding, Zhong ,  Gottermeier, William Franklin ,  Swick, Aaron Michael

    IPC分类号： G01N33/49 ,  B01L3/00 ,  G01N33/558

    CPC分类号： A61B5/150343 ,  A61B5/14507 ,  A61B5/1468 ,  A61B5/150213 ,  A61B5/157 ,  A61B10/007 ,  B01L3/502 ,  B01L2200/025 ,  B01L2200/0684 ,  B01L2300/0681 ,  B01L2300/087 ,  B01L2300/161 ,  B01L2400/0406 ,  B01L2400/0487 ,  B01L2400/0644 ,  G01N33/49

    摘要： A sample collection device (10) for a fluid, such as body fluids like blood, urine or saliva, includes: a substantially disk-shaped body having a periphery; a capillary channel (11) extending through the body and bounded by the periphery, having a first end (12) and a second end (13), wherein the first end (12) is adapted to draw the fluid into the channel (11) by capillary action; a sample collection well (14) located in the vicinity of the second end (13) and in fluid communication with the capillary channel (11); and an axis of rotation extending through the center of the disk and which is substantially perpendicular to the upper surface of the disk-shaped body. In a preferred embodiment, the sample collection device is adapted to rotate about the axis of rotation within a cartridge of a fluid measuring device, such as a lateral flow assay, wherein the cartridge has a housing comprising an air vent (32) in fluid communication with the capillary channel (11) when the disk is rotated in a first position.

    摘要翻译： 用于流体（如血液，尿液或唾液）的体液的样品收集装置（10）包括：具有周边的大致圆盘状体; 延伸穿过主体并由周边限定的毛细通道（11）具有第一端（12）和第二端（13），其中第一端（12）适于将流体吸入通道（11）中， 通过毛细作用; 位于第二端（13）附近并与毛细通道（11）流体连通的样品收集阱（14）; 以及延伸穿过盘的中心并且基本上垂直于盘形体的上表面的旋转轴线。 在优选实施例中，样品收集装置适于围绕流体测量装置的药筒内的旋转轴线旋转，例如侧流测定，其中药筒具有壳体，该壳体包括流体连通的通气孔（32） 当盘在第一位置旋转时与毛细管通道（11）接合。

    Assay device having controllable sample size
    6.
    发明公开
    Assay device having controllable sample size 有权
    分析仪器（Probengröße）

    公开(公告)号：EP2618152A1

    公开(公告)日：2013-07-24

    申请号：EP13151797.1

    申请日：2013-01-18

    申请人： ORTHO-CLINICAL DIAGNOSTICS, INC.

    发明人： Scalice, Edward R. ,  Hosimer, Philip C. ,  Ding, Zhong ,  Kanaley, James D. ,  Tomasso, David A. ,  Salotto, Daniel P. ,  Warren, Timothy C.

    IPC分类号： G01N33/543 ,  G01N33/558

    CPC分类号： G01N33/5302 ,  G01N33/53 ,  G01N33/54386 ,  G01N33/558

    摘要： Disclosed is an assay device which comprises a liquid sample addition zone, a reagent zone, a detection zone, and a wicking zone, all defining a fluid flow path. The device further comprises a reagent addition zone along and in fluid communication with the fluid flow path downstream of the sample addition zone and upstream of the detection zone. An interrupting wash is added at this reagent addition zone in accordance with the method of the subject invention to control sample volume. The interrupting wash fluid is added at a predetermined fill volume on the chip device and also serves to wash the detection channel and fill the remaining chip volume.

    摘要翻译： 公开了一种测定装置，其包括液体样品加入区，试剂区，检测区和芯吸区，均定义流体流动路径。 该装置还包括沿着样品添加区的下游和检测区的上游与流体流动路径流体连通的试剂添加区。 根据本发明的方法在该试剂添加区添加中断洗涤物以控制样品体积。 中断洗涤流体以芯片装置上的预定填充体积加入，并且还用于清洗检测通道并填充剩余的芯片体积。