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公开(公告)号：EP2521549A1
公开(公告)日：2012-11-14
申请号：EP10841742.9
申请日：2010-12-30
发明人： SUZUKI, Masaki , KONDO, Kazumi , KURIMURA, Muneaki , VALLURU, Krishna, Reddy , TAKAHASHI, Akira , KURODA, Takeshi , TAKAHASHI, Haruka , FUKUSHIMA, Tae , MIYAMURA, Shin , GHOSH, Indranath , DOGRA, Abhishek , HARRIMAN, Geraldine , ELDER, Amy , SHIMIZU, Satoshi , HODGETTS, Kevin, J. , NEWCOM, Jason, S.
IPC分类号： A61K31/52
CPC分类号： C07D401/04 , A61K31/517 , A61K45/06 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D487/04 , C07D495/04
摘要： Methods of treating disorders using compounds that modulate striatal-enriched tyrosine phosphatase (STEP) are described herein. Exemplary disorders include schizophrenia and cognitive deficit.
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公开(公告)号：EP2521549B1
公开(公告)日：2016-08-17
申请号：EP10841742.9
申请日：2010-12-30
发明人： SUZUKI, Masaki , KONDO, Kazumi , KURIMURA, Muneaki , VALLURU, Krishna, Reddy , TAKAHASHI, Akira , KURODA, Takeshi , TAKAHASHI, Haruka , FUKUSHIMA, Tae , MIYAMURA, Shin , GHOSH, Indranath , DOGRA, Abhishek , HARRIMAN, Geraldine , ELDER, Amy , SHIMIZU, Satoshi , HODGETTS, Kevin, J. , NEWCOM, Jason, S.
IPC分类号： A61K45/06 , A61K31/517 , C07D401/14 , C07D405/14 , C07D413/14 , C07D401/04 , C07D403/04 , C07D409/14 , C07D417/14 , C07D487/04 , C07D495/04
CPC分类号： C07D401/04 , A61K31/517 , A61K45/06 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D487/04 , C07D495/04
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3.发明公开
公开(公告)号：EP2726485A1
公开(公告)日：2014-05-07
申请号：EP12748285.9
申请日：2012-06-28
发明人： SUZUKI, Masaki , KONDO, Kazumi , KURIMURA, Muneaki , VALLURU, Krishna Reddy , TAKAHASHI, Akira , KURODA, Takeshi , TAKAHASHI, Haruka , FUKUSHIMA, Tae , MIYAMURA, Shin , GHOSH, Indranath , DOGRA, Abhishek , HARRIMAN, Geraldine , ELDER, Amy , SHIMIZU, Satoshi , HODGETTS, Kevin, J. , NEWCOM, Jason, S.
IPC分类号： C07D487/04
CPC分类号： C07D405/14 , A61K31/517 , A61K45/06 , C07D401/04 , C07D401/14 , C07D403/04 , C07D413/14 , C07D417/14 , C07D487/04
摘要： Methods of treating disorders using compounds (I) that modulate stri-atal-enriched tyrosine phosphatase (STEP) are described herein. Exemplary disorders include schizophrenia and cognitive deficit. Formula (I).
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公开(公告)号：EP2435046A1
公开(公告)日：2012-04-04
申请号：EP10726330.3
申请日：2010-05-27
IPC分类号： A61K31/519 , C07D471/04 , A61P25/22 , A61P25/24
CPC分类号： C07D471/04 , A61K31/519 , C07D491/048 , C07D491/056 , C07D495/04 , C07D519/00
摘要： The present invention provides a novel heterocyclic compound. A heterocyclic compound represented by general formula (1) wherein, R
1 and R
2 , each independently represent hydrogen; a phenyl lower alkyl group that may have a substituent(s) selected from the group consisting of a lower alkyl group and the like on a benzene ring and/or a lower alkyl group; or a cyclo C3-C8 alkyl lower alkyl group; or the like; R
3 represents a lower alkynyl group or the like; R
4 represents a phenyl group that may have a substituent(s) selected from the group consisting of a 1,3,4-oxadiazolyl group that may have e.g., halogen or a heterocyclic group selected from pyridyl group and the like; the heterocyclic group may have at least one substituent(s) selected from a lower alkoxy group and the like or a salt thereof.-
公开(公告)号：EP2435046B1
公开(公告)日：2013-09-04
申请号：EP10726330.3
申请日：2010-05-27
IPC分类号： C07D491/048 , C07D491/056 , C07D495/04 , C07D519/00 , C07D471/04 , A61K31/519 , A61P25/22 , A61P25/24
CPC分类号： C07D471/04 , A61K31/519 , C07D491/048 , C07D491/056 , C07D495/04 , C07D519/00
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公开(公告)号：EP4347597A1
公开(公告)日：2024-04-10
申请号：EP22732679.0
申请日：2022-06-01
发明人： UEMATSU, Yukitaka , OKADA, Minoru , SAITO, Akihiro , TAKAHASHI, Akira , NAKAMURA, Yuichi , HANARI, Taiki , MENJO, Yasuhiro , YAMAUCHI, Takahito , YAMAGUCHI, Atsushi , YUKI, Yohei , WATANABE, Kenji , MATSUDA, Satoshi
IPC分类号： C07D487/04 , A61P17/00 , A61P37/00 , A61K31/519
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