专利检索 ap:("PACIFIC BIOSCIENCES CALIFORNIA") AND inv:"CLARK SONYA" 第 1 页

1.

发明公开
GENERATION OF MODIFIED POLYMERASES FOR IMPROVED ACCURACY IN SINGLE MOLECULE SEQUENCING 有权
标题翻译：单分子测序法提高修饰聚合物的生成精度

公开(公告)号：EP2271751A4

公开(公告)日：2011-09-14

申请号：EP09755183

申请日：2009-03-30

申请人： PACIFIC BIOSCIENCES CALIFORNIA

发明人： CLARK SONYA , BIBILLO AREK , PELUSO PAUL , CHRISTIANS FRED , HE MOLLY , PARK INSIL , LEE HAROLD , BJORNSON KEITH , JIA LEI , EMIG ROBIN

IPC分类号： C12Q1/68 , C12N9/12 , C12Q1/48

CPC分类号： C12N9/1252 , C12Q1/6844 , C12Q1/6869 , C12Q2521/101

2.

发明公开
POLYMERASES FOR NUCLEOTIDE ANALOGUE INCORPORATION 有权
标题翻译：聚合酶FOR核苷类似物团

公开(公告)号：EP1963536A4

公开(公告)日：2010-03-03

申请号：EP06848948

申请日：2006-12-21

申请人： PACIFIC BIOSCIENCES CALIFORNIA

发明人： HANZEL DAVID K , OTTO GEOFF , MURPHY DEVON , PELUSO PAUL , PHAM THANG , RANK DAVID R , MITSIS PAUL , CHRISTIANS FRED C , BIBILLO AREK , PARK INSIL , CLARK SONYA , LYLE JOHN

IPC分类号： C12Q1/68

CPC分类号： C12N9/1252 , C07K2319/20 , C12P19/34 , C12Q1/6827 , C12Q1/6869 , C12Y207/07007 , Y02P20/52

摘要： Compositions that include polymerases with features for improving entry of nucleotide analogues into active site regions and for coordinating with the nucleotide analogues in the active site region are provided. Methods of making the polymerases and of using the polymerases in sequencing and DNA replication and amplification as well as kinetic models of polymerase activity and computer-implemented methods of using the models are also provided.