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公开(公告)号：EP1173178A4
公开(公告)日：2002-09-04
申请号：EP00916324
申请日：2000-03-14
发明人： EL-RASHIDY RAGAB
IPC分类号： A61K47/40 , A61K31/201 , A61K31/4164 , A61K31/437 , A61K31/473 , A61K31/505 , A61K31/517 , A61K31/522 , A61K31/568 , A61K31/5685 , A61P15/10 , A61P43/00 , A61K31/44
CPC分类号： A61K31/505 , A61K31/47 , A61K2300/00
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2.发明公开
公开(公告)号：EP1017371A4
公开(公告)日：2000-07-12
申请号：EP98919989
申请日：1998-04-29
IPC分类号： A61K9/00 , A61K9/22 , A61K31/137 , A61K31/277 , A61K31/473 , A61K31/485 , A61K31/5377 , A61K47/02 , A61K47/12 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/38 , A61K47/42 , A61P15/10
CPC分类号： A61K31/5377 , A61K9/006 , A61K9/2018 , A61K9/2054 , A61K31/137 , A61K31/277 , A61K31/473 , A61K31/485
摘要： A composition providing a relatively slow release of water-soluble drugs, such as apomorphine, for delivery via the sublingual or buccal routes.
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公开(公告)号：EP0800364A4
公开(公告)日：1998-04-01
申请号：EP95944522
申请日：1995-12-22
发明人： DURIF FRANCK , EL-RASHIDY RAGAB
IPC分类号： A61K9/70 , A61K31/485 , A61K47/32 , A61K47/38 , A61F13/00
CPC分类号： A61K9/7069 , A61K9/0014 , A61K9/7092 , A61K31/485 , A61K47/32 , A61K47/38 , Y10S514/944
摘要： Dosage forms for the transdermal administration of apomorphine are described. The dosage forms are water-soluble gel compositions that contain apomorphine, optionally together with a permeation enhancer, or transdermal patches.
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公开(公告)号：EP1180021A4
公开(公告)日：2005-01-19
申请号：EP00932038
申请日：2000-05-03
发明人： EL-RASHIDY RAGAB , MCMAHON CHRIS
IPC分类号： A61J1/03 , A61J7/04 , A61K9/20 , A61K31/4525 , A61P15/00 , C07D405/12
CPC分类号： A61K31/4525
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公开(公告)号：EP0931080A4
公开(公告)日：2001-01-24
申请号：EP97939837
申请日：1997-09-08
发明人： RONSEN BRUCE , EL-RASHIDY RAGAB
IPC分类号： C07D405/12 , A61K31/435 , A61K31/4525 , A61P15/10 , C07D401/12 , C07D405/02
CPC分类号： C07D401/12 , A61K31/4525
摘要： A free-flowing, amorphous paroxetine hydrochloride-ethanol composition suitable as a therapeutic agent for premature ejaculation can be prepared by dissolving paroxetine free base in a hydrochloric acid-ethanol solution followed by drying. In a preferred embodiment, the amount of ethanol present in the amorphous product is in the range of 1 to 4 weight percent based on paroxetine hydrochloride. The amorphous product is stable and substantially non-hygroscopic.
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公开(公告)号：EP1056419A4
公开(公告)日：2007-05-02
申请号：EP99905497
申请日：1999-01-28
发明人： EL-RASHIDY RAGAB , RONSEN BRUCE
IPC分类号： C07D221/18 , A61K31/473 , A61K31/485 , A61K47/40 , A61P15/00 , A61F6/06
CPC分类号： A61K31/485
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7.发明公开CONTROLLED RELEASE OF SILDENAFIL DELIVERED BY SUBLINGUAL OR BUCCAL ADMINISTRATION 审中-公开控制主FREISETZNUG舌下或口腔给予西地那非
公开(公告)号：EP1171134A4
公开(公告)日：2005-01-05
申请号：EP00916328
申请日：2000-03-14
发明人： EL-RASHIDY RAGAB
IPC分类号： A61K9/00 , A61K9/22 , A61K31/519 , A61K47/04 , A61K47/10 , A61K47/30 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/38 , A61K47/46 , A61P15/10 , A61K31/505
CPC分类号： A61K9/0056 , A61K31/519
摘要： A controlled release composition containing sildenafil for delivery via the sublingual or buccal routes. In addition to sildenafil the composition includes an osmotic agent, a swellable hydrophilic carrier, and a water dispersible polymer.
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公开(公告)号：EP1105129A4
公开(公告)日：2003-11-12
申请号：EP99933642
申请日：1999-07-01
发明人： EL-RASHIDY RAGAB , RONSEN BRUCE
IPC分类号： A61K31/435 , A61K31/473 , A61P15/10 , A61P25/16 , A61P25/22 , A61K31/44
CPC分类号： A61K31/473
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9.发明公开APOMORPHINE-CONTAINING DOSAGE FORMS FOR AMELIORATING MALE ERECTILE DYSFUNCTION 有权阿朴吗啡含剂型男性勃起功能障碍的改进
公开(公告)号：EP1094799A4
公开(公告)日：2002-05-08
申请号：EP99930538
申请日：1999-06-22
发明人： EL-RASHIDY RAGAB , RONSEN BRUCE
IPC分类号： A61K31/473 , A61K9/00 , A61K31/00 , A61K31/4439 , A61K31/485 , A61K31/5415 , A61K49/00 , A61P15/10
CPC分类号： A61K9/0056 , A61K31/00 , A61K31/473 , A61K31/485 , A61K49/0004
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10.发明公开APOMORPHINE-CONTAINING DOSAGE FORM FOR AMELIORATING MALE ERECTILE DYSFUNCTION 审中-公开男性勃起功能障碍的APOMORPHINHALTIGE剂型RELIEF
公开(公告)号：EP1448194A4
公开(公告)日：2005-08-10
申请号：EP02773812
申请日：2002-10-21
发明人： EL-RASHIDY RAGAB , RONSEN BRUCE
IPC分类号： C07D221/18 , A61K9/00 , A61K31/00 , A61K31/4045 , A61K31/44 , A61K31/454 , A61K31/472 , A61K31/473 , A61K31/485 , A61K31/506 , A61K45/00 , A61K49/00 , A61P1/08 , A61P9/02 , A61P15/10 , A61P43/00
CPC分类号： A61K9/0056 , A61K31/00 , A61K31/4045 , A61K31/44 , A61K31/472 , A61K31/473 , A61K31/485 , A61K31/506 , A61K49/0004
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