公开(公告)号：EP2849657A4

公开(公告)日：2016-02-17

申请号：EP13790201

申请日：2013-05-13

申请人： PULSE THERAPEUTICS INC

发明人： CREIGHTON FRANCIS M ,  SABO MICHAEL ,  CHRISTOPHER ,  EPPLIN GERARD ,  WACHTMAN JAMES CHRISTOPHER

IPC分类号： A61B17/3207 ,  A61B17/22 ,  A61B34/30 ,  A61N2/12

CPC分类号： A61B17/3207 ,  A61B17/320758 ,  A61B34/25 ,  A61B34/30 ,  A61B34/73 ,  A61B2017/00345 ,  A61B2017/00411 ,  A61B2017/22082 ,  A61B2017/320004 ,  A61N2/004 ,  A61N2/12

摘要： Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator. In one embodiment, the systems and methods relate to the control of magnetic nanoparticles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. Magnetic nanoparticles are provided having a non-specialized chemical coating facilitating association with a chemical composition by a user before infusion. Systems are provided for delivering a consistent infusion mass of magnetic nanoparticles to a patient.