公开(公告)号：EP1665130A1

公开(公告)日：2006-06-07

申请号：EP04785100.1

申请日：2004-09-24

申请人： Paieon Inc.

发明人： KLAIMAN, Moshe ,  ZARKH, Michael

IPC分类号： G06K9/00

CPC分类号： G06T7/564

摘要： Embodiments of the present invention include methods and systems for three-dimensional reconstruction of a tubular organ (for example, coronary artery) using a plurality of two-dimensional images. Some of the embodiments may include displaying a first image of a vascular network, receiving input for identifying on the first image a vessel of interest, tracing the edges of the vessel of interest including eliminating false edges of objects visually adjacent to the vessel of interest, determining substantially precise radius and densitometry values along the vessel, displaying at least a second image of the vascular network, receiving input for identifying on the second image the vessel of interest, tracing the edges of the vessel of interest in the second image, including eliminating false edges of objects visually adjacent to the vessel of interest, determining substantially precise radius and densitometry values along the vessel in the second image, determining a three dimensional reconstruction of the vessel of interest and determining fused area (cross-section) measurements along the vessel and computing and presenting quantitative measurements, including, but not limited to, true length, percent narrowing (diameter and area), and the like.

摘要翻译： 本发明的实施例包括使用多个二维图像的管状器官（例如冠状动脉）的三维重建的方法和系统。 一些实施例可以包括显示血管网络的第一图像，接收用于在第一图像上识别感兴趣的血管的输入，跟踪感兴趣的血管的边缘，包括消除视觉上与感兴趣血管相邻的物体的假边缘， 确定沿着血管的基本精确的半径和密度测定值，显示血管网络的至少第二图像，接收用于在第二图像上识别感兴趣血管的输入，跟踪第二图像中感兴趣血管的边缘，包括消除 在视觉上与感兴趣的血管相邻的物体的假边缘，沿着第二图像中的血管确定基本上精确的半径和密度测定值，确定感兴趣血管的三维重建并且确定沿着血管的融合区域（横截面）测量 并且计算和呈现定量测量，包括但不限于， 真实长度，百分比变窄（直径和面积）等。

公开(公告)号：EP1654704A2

公开(公告)日：2006-05-10

申请号：EP04744972.3

申请日：2004-07-14

申请人： Paieon Inc.

发明人： ZARKH, Michael ,  KLAIMAN, Moshe

IPC分类号： G06T7/20

CPC分类号： G06T11/005 ,  A61B5/7285 ,  A61B6/503 ,  A61B6/504 ,  A61B6/541 ,  G06T7/20 ,  G06T2211/404 ,  G06T2211/412

摘要： A method and system for quantifying a cyclic motion within a series of images depicting a moving object subject to composite motion containing a cyclic component and a non-cyclic component of lower frequency than the cyclic component. Composite motion is computed. The non-cyclic component is computed as the integral of motion over a motion cycle. The non-cyclic component is subtracted from the composite motion so as to obtain the cyclic component.

公开(公告)号：EP2268202A1

公开(公告)日：2011-01-05

申请号：EP08738228.9

申请日：2008-04-17

申请人： Paieon Inc.

发明人： ZARKH, Michael ,  BLUMENFELD, Amir ,  KLAIMAN, Moshe

IPC分类号： A61B5/05

CPC分类号： A61B6/12 ,  A61B6/481 ,  A61B6/504

摘要： A method and apparatus for navigating a therapeutic device to a location in a moving organ. A feature is identified in one reference image, such as a calcified spot. Then the target location for the device is determined. If the feature and the target location are not shown on the same frame, registration is performed, and the geometric relation between the feature and the target location is determined. On the positioning stage, the feature is identified in a positioning image, then the target location is indicated on the image. The user then manipulates the device, also visible on the positioning image to the target location. If the feature is not identified automatically in the positioning image, the target location is assumed at the current location, and the feature is marked, which assists the user in identifying the real location of the feature, and manipulating the device to the target location.

公开(公告)号：EP1804658A2

公开(公告)日：2007-07-11

申请号：EP05788593.1

申请日：2005-09-25

申请人： Paieon Inc.

发明人： ZARKH, Michael ,  BARLEV, Omer ,  KLAIMAN, Moshe

IPC分类号： A61B5/05

CPC分类号： A61B6/504 ,  G06T7/33 ,  G06T7/38 ,  G06T2207/30101

摘要： An apparatus and method for fusing images, views and data acquired prior to a medical operation by a medical imaging device with images, views and data acquired by another medical imaging device during the operation. The acquired and fused data includes identification and classification of plaque deposited along blood vessels.

摘要翻译： 用于融合图像，观点和通过用图像，观点和在操作过程中由另一个医学成像装置采集的数据的医学成像装置之前在医疗手术获取的数据的装置和方法。 所获取的和稠合的数据包括沿着沉积血管斑块的鉴定和分类。

公开(公告)号：EP2081495A2

公开(公告)日：2009-07-29

申请号：EP06809776.5

申请日：2006-10-22

申请人： Paieon Inc.

发明人： ZARKH, Michael ,  KLAIMAN, Moshe

IPC分类号： A61B6/00

CPC分类号： A61B6/12 ,  A61B6/481 ,  A61B6/487 ,  A61B6/504 ,  A61B6/541 ,  A61B6/547 ,  A61B34/10 ,  A61B34/20 ,  A61B90/36 ,  A61B2034/105 ,  A61B2034/107 ,  A61B2034/2051 ,  A61B2090/365 ,  A61B2090/376 ,  A61F2/95 ,  G06T7/32 ,  G06T7/38 ,  G06T2207/10116 ,  G06T2207/30048 ,  G06T2207/30101

摘要： An apparatus and method for detecting, tracking and registering a device within a tubular organ of a subject. The method and apparatus are designed to allow navigation of a first device in a stenosis area of a tubular organ of a subject, noting the coordinates of the first device, and navigating a second device to the coordinates of the first device, for avoiding situations wherein walls of the tubular organ injured by the first device develop symptoms such as restenosys or thrombosis if the second device is shorter than the first device, or is misplaced relatively to the first device.

公开(公告)号：EP1869637A1

公开(公告)日：2007-12-26

申请号：EP05718933.4

申请日：2005-03-31

申请人： Paieon Inc.

发明人： ZARKH, Michael ,  KLAIMAN, Moshe ,  EVRON, Rami

IPC分类号： G06T7/00 ,  G06K9/64

CPC分类号： G06K9/6203 ,  A61B6/12 ,  A61B6/481 ,  A61B6/504 ,  A61B6/541 ,  G06T7/32 ,  G06T7/38 ,  G06T2207/30101

摘要： An apparatus and method for detecting, tracking and registering a device within a tubular organ of a subject. The devices include guide wire tip or therapeutic devices, and the detection and tracking uses fluoroscopic images taken prior to or during a catheterization operation. The devices are fused with images or projections of models depicting the tubular organs.

摘要翻译： 一种用于检测，跟踪和记录受试者的管状器官内的装置的装置和方法。 这些装置包括导线尖端或治疗装置，并且检测和跟踪使用在导管插入术之前或期间拍摄的荧光透视图像。 这些装置与描绘管状器官的模型的图像或突起融合。

公开(公告)号：EP1899007A1

公开(公告)日：2008-03-19

申请号：EP05737645.1

申请日：2005-05-03

申请人： Paieon Inc.

发明人： ASSIS, Tsuriel ,  KLAIMAN, Moshe ,  ZARKH, Michael

IPC分类号： A61N1/372 ,  A61B6/00

CPC分类号： A61B6/12 ,  A61B6/466 ,  A61B6/481 ,  A61B6/504 ,  A61B6/5235 ,  A61N1/08

摘要： An apparatus and method for placing a device in a body area of a patient, by: tracking the device over a 3-dimensional model of the body area; activating the device at different locations in the body area; measuring the response signal or parameter caused by the activation; storing the locations as well as the response signals; choosing an optimal location for the device base in the stored response signals and navigating the device to the optimal location.

公开(公告)号：EP1830701A1

公开(公告)日：2007-09-12

申请号：EP05762107.0

申请日：2005-07-24

申请人： Paieon Inc.

发明人： ASSIS, Tsuriel ,  KUPER, Asher ,  ZARKH, Michael ,  KLAIMAN, Moshe

IPC分类号： A61B5/05

CPC分类号： A61B5/0275 ,  A61B6/507

摘要： An apparatus and method for the determination of the flow, the coronary reserve and relative coronary reserve of a specific coronary artery. The apparatus and method employ a three-dimensional model (50) providing the volume of a segment of the artery at a plurality of points in time, and disclose various options (56) for determining the arterial flow through the artery segment during one or more heart beat cycles or parts thereof. The determination of the coronary reserve (62) and relative coronary reserve (64) follow from the volume (54) and the flow through the artery. Alternatively, the coronary reserve is determined directly from a velocity profile relating to one or more fixed artery segments and the three-dimensional model.