公开(公告)号：EP2383285B1

公开(公告)日：2017-07-12

申请号：EP11157383.8

申请日：2007-02-05

申请人： Peptcell Limited

发明人： Caparrós-Wanderley, Wilson Romero ,  Stoloff, Gregory Alan

IPC分类号： C07K14/005 ,  A61K39/145 ,  A61K38/12

CPC分类号： A61K39/145 ,  A61K39/12 ,  A61K2039/55566 ,  A61K2039/57 ,  A61K2039/572 ,  A61K2039/70 ,  C07K7/08 ,  C07K14/005 ,  C07K14/11 ,  C12N2760/16122 ,  C12N2760/16134 ,  C12N2760/16171 ,  C12N2760/16222 ,  C12N2760/16234 ,  C12N2760/16271

摘要： Provided is a polypeptide having no more than 100 amino acids, which polypeptide comprises one or more sequences having at least 60% homology with any of SEQ ID 1-6, or comprises two or more epitopes having 7 amino acids or more, each epitope having at least 60% homology with a sub-sequence of any of SEQ ID 1-6 that has the same length as the epitope: wherein, the polypeptide is immunogenic in a vertebrate expressing a major histocompatibility complex (MHC) allele, and wherein the polypeptide is not a complete influenza virus protein.

公开(公告)号：EP2383284B1

公开(公告)日：2016-08-24

申请号：EP11157382.0

申请日：2007-02-05

申请人： Peptcell Limited

发明人： Caparrós-Wanderley, Wilson Romero ,  Stoloff, Gregory Alan

IPC分类号： C07K14/11 ,  A61K39/145 ,  A61K39/00

CPC分类号： A61K39/145 ,  A61K39/12 ,  A61K2039/55566 ,  A61K2039/57 ,  A61K2039/572 ,  A61K2039/70 ,  C07K7/08 ,  C07K14/005 ,  C07K14/11 ,  C12N2760/16122 ,  C12N2760/16134 ,  C12N2760/16171 ,  C12N2760/16222 ,  C12N2760/16234 ,  C12N2760/16271

摘要： Provided is a polypeptide having no more than 100 amino acids, which polypeptide comprises one or more sequences having at least 60% homology with any of SEQ ID 1-6, or comprises two or more epitopes having 7 amino acids or more, each epitope having at least 60% homology with a sub-sequence of any of SEQ ID 1-6 that has the same length as the epitope: wherein, the polypeptide is immunogenic in a vertebrate expressing a major histocompatibility complex (MHC) allele, and wherein the polypeptide is not a complete influenza virus protein.

公开(公告)号：EP2392587B1

公开(公告)日：2016-05-04

申请号：EP11167363.8

申请日：2007-03-09

申请人： Peptcell Limited

发明人： Stoloff, Gregory Alan ,  Caparrós-Wanderley, Wilson Romero

IPC分类号： C07K14/16 ,  A61K38/16 ,  A61P31/18

CPC分类号： A61K39/21 ,  A61K39/12 ,  A61K2039/55544 ,  C07K14/005 ,  C07K2319/01 ,  C12N7/00 ,  C12N2740/16034 ,  C12N2740/16071 ,  C12N2740/16322 ,  C12N2740/16334

摘要： Provided is a polypeptide having no more than 100 amino acids, which polypeptide comprises one or more sequences having at least 60% homology with any of SEQ ID 1-4, or comprises two or more epitopes having 7 amino acids or more, each epitope having at least 60% homology with a sub-sequence of any of SEQ ID 1-4 that has the same length as the epitope: SEQ ID 1 GDTWAGVEAIIRILQQLLFIHFRIGCQHSR SEQ ID 2 KVGSLQYLALTALITPKKIKPPLPSVKKLTEDRWNKPQKT SEQ ID 3 EPVPLQLPPLERLTLDCSEDCGTSGTQ SEQ ID 4 YKGALDLSHFLKEKGGLEGLIYSQKRQDILDLWVYHTQGYFPD wherein, the polypeptide is immunogenic in a vertebrate expressing a major histocompatibility complex (MHC) allele, and wherein the polypeptide is not a complete HIV virus protein.