-
公开(公告)号：EP1311481A1
公开(公告)日：2003-05-21
申请号：EP01960493.3
申请日：2001-07-12
发明人： BERIA, Italo , COZZI, Paolo , MONGELLI, Nicola , NESI, Marcella
IPC分类号： C07D207/34
CPC分类号： C07D207/34
摘要： Herewith provided is a process for preparing useful intermediates in the preparation of distamycin derivatives possessing antitumor activity, said derivatives having the formula reported in the specification, by using distamycin A as the starting material.
-
2.发明公开SUBSTITUTED PYRROLO-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS 有权作为激酶抑制剂的合适的取代PYRROLOPYRAZOLDERIVATE
公开(公告)号：EP1575954A2
公开(公告)日：2005-09-21
申请号：EP03799536.2
申请日：2003-12-04
发明人： BRASCA, Maria, Gabriella , AMICI, Raffaella , FANCELLI, Daniele , NESI, Marcella , ORSINI, Paolo , ORZI, Fabrizio , ROUSSEL, Patrick , VULPETTI, Anna , PEVARELLO, Paolo
IPC分类号： C07D487/00
CPC分类号： C07D487/04 , A61K31/4162 , A61K31/454 , A61K31/496 , A61K31/5377 , A61K45/06 , A61N5/10
摘要： Compounds represented by formula (Ia) or (lb) and wherein R and R1 are as defined in the description, and pharmaceutically acceptable salts thereof, are disclosed; the said compounds are useful in the treatment of cell cycle proliferative disorders, e.g. cancer, associated with an altered cell cycle dependent kinase activity.
-
3.发明公开PHENYLACETAMIDO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS 有权苯乙酰胺基噻唑化合物，工艺作为生产，它们作为抗肿瘤药
公开(公告)号：EP1406899A2
公开(公告)日：2004-04-14
申请号：EP02760213.5
申请日：2002-07-02
发明人： PEVARELLO, Paolo , AMICI, Raffaella , VILLA, Manuela , SALOM, Barbara , VULPETTI, Anna , VARASI, Mario , BRASCA, Maria, Gabriella , TRAQUANDI, Gabriella , NESI, Marcella
IPC分类号： C07D417/12 , C07D277/46 , A61K31/425 , A61P35/00
CPC分类号： C07D417/12 , C07D277/46
摘要： Compounds represented by formula (I), as defined in the description, wherein R is a hydrogen atom or a methyl group and R1 is a group as defined in the specification, or a pharmaceutically acceptable salt thereof, are disclosed; the said compounds are useful in the treatment of cell proliferative disorders, e.g. cancer, associated with an altered cell cycle dependent kinase activity.
-
-
搜索结果
3 条记录 (耗时 0.011 秒)
