公开(公告)号：EP1377542A1

公开(公告)日：2004-01-07

申请号：EP02704504.6

申请日：2002-02-12

申请人： Pharmacor Inc.

发明人： STRANIX, Brent, Richard ,  SAUVE, Gilles ,  BOUZIDE, Abderrahim ,  COTE, Alexandre ,  BERUBE, Gervais ,  SOUCY, Patrick ,  ZHAO, Yongsen ,  YELLE, Jocelyn

IPC分类号： C07C311/19 ,  C07D209/16 ,  C07C311/46 ,  C07D333/34 ,  C07D333/60 ,  C07C311/42 ,  C07D295/215 ,  C07C327/48 ,  C07D409/12 ,  A61K31/198 ,  A61K31/405 ,  A61K31/381 ,  A61K31/5375 ,  A61P31/18

CPC分类号： C07D295/185 ,  A61K38/00 ,  C07C311/19 ,  C07C311/42 ,  C07C311/46 ,  C07C323/60 ,  C07C327/44 ,  C07C327/48 ,  C07C2601/08 ,  C07D209/16 ,  C07D333/34 ,  C07D333/60 ,  C07K5/0215

摘要： A compound selected from the group consisting of a compound of formula I or formula II: (I) (II) wherein n is 3 or 4 wherein Cx is selected from the group consisting of -COOM, COOR6, -CHO, -CH2OR7, -CH2OCOR8, -CONHR9 and -CONR10R11, wherein M is an alkali metal or alkaline earth metal, wherein R2 is selected from the group consisting of a benzenesulfonyl group of formula III, or formula IV : (III) (IV) and when the compound of formula (I) and (II) comprises an amino group pharmaceutically acceptable ammonium salts thereof, wherein R1, R2, Cx, n, R3, R4, R5, Y are as defined in the specification.