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    IMPROVED RADIATION THERAPY PLANNING PROCEDURE
    3.
    发明公开
    IMPROVED RADIATION THERAPY PLANNING PROCEDURE 审中-公开
    方法改良的放射治疗计划

    公开(公告)号：EP1981593A2

    公开(公告)日：2008-10-22

    申请号：EP07700651.8

    申请日：2007-01-22

    申请人： Philips Intellectual Property & Standards GmbH ,  Koninklijke Philips Electronics N.V.

    发明人： SPIES, Lothar ,  HUMMEL, Helga ,  RIBBING, Carolina ,  HOFFMANN, Ralf ,  BACHMANN, Peter Klaus

    IPC分类号： A61N5/10

    CPC分类号： A61N5/1031

    摘要： An improved radiation therapy planning procedure is suggested. The procedure comprises the steps of specifying and determining the absolute grade of cell degeneracy by in-vitro tests, whereby marker(s) indicative for specific cell degeneracy are detected and quantified, establishing a biology-based segmentation of areas with similar grade of relative cell degeneracy and applying the absolute grade of cell degeneracy to the biology-based segmentation data, thereby establishing an improved radiation therapy planning procedure. Moreover, the present invention suggests a system for an improved radiation therapy planning procedure and its use in procedures of diagnosis and/or therapy management of cancer.

    RECONSTRUCTION OF LOCAL PATIENT DOSES IN COMPUTED TOMOGRAPHY
    4.
    发明公开
    RECONSTRUCTION OF LOCAL PATIENT DOSES IN COMPUTED TOMOGRAPHY 有权
    重建计算出的局部病人可以的

    公开(公告)号：EP1590045A1

    公开(公告)日：2005-11-02

    申请号：EP04703226.3

    申请日：2004-01-19

    申请人： Philips Intellectual Property & Standards GmbH ,  Koninklijke Philips Electronics N.V.

    发明人： BOTTERWECK, Henrik ,  SPIES, Lothar

    IPC分类号： A61N5/10 ,  A61B6/03

    CPC分类号： A61B6/032 ,  A61N5/1031 ,  Y10S128/922

    摘要： In order to reduce an x-ray dose applied to a patient, it is necessary to know the dose absorbed by the patient. According to the present invention, there is provided a method of determining a local patient dose applied to a patient where after the reconstruction of the scan data into a diagnostic image, the scan data are back­projected into the patient volume, using the attenuation information of the diagnostic image to form a spatially varying photon fluence map. In parallel, the diagnostic image is segmented into anatomical structures to which dose-weighting factors are assigned. The locally absorbed dose is then calculated on the basis of the fluence map and the corresponding dose weights.

    A METHOD TO INDIVIDUALIZE KINETIC PARAMETER ESTIMATION FOR DYNAMIC MOLECULAR IMAGING PROCEDURES
    8.
    发明公开
    A METHOD TO INDIVIDUALIZE KINETIC PARAMETER ESTIMATION FOR DYNAMIC MOLECULAR IMAGING PROCEDURES 审中-公开
    推求的个体化动力学参数动态分子成像过程方法

    公开(公告)号：EP2002398A2

    公开(公告)日：2008-12-17

    申请号：EP07735168.2

    申请日：2007-03-19

    申请人： Koninklijke Philips Electronics N.V. ,  Philips Intellectual Property & Standards GmbH

    发明人： SPIES, Lothar ,  NARAYANAN, Manoj ,  BAKKER, Bart, J.

    IPC分类号： G06T7/00 ,  G06T5/00

    CPC分类号： A61B5/02755 ,  G06F19/00 ,  G06T7/20 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/30004 ,  G16H50/50

    摘要： A method within dynamic molecular imaging comprising dynamically estimating a first parameter (&bgr;(x)) and a second parameter (k(x)) of an activity function describing the bio distribution of an administered tracer, is disclosed. More specifically, the method comprises specifying a first target variance (&sgr;&bgr;,T(x)) and a second target variance (&sgr;&bgr;,T(x)) of the first parameter (&bgr;(x)) and the second parameter (k(x)) of the activity function, respectively; initiating an image acquisition; reconstructing the first parameter (&bgr;(x)) and the second parameter (k(x)); reconstructing a first associated variance (&sgr;&bgr;(x)) and a second associated variance (&sgr;k(x)) of the first parameter (&bgr;(x)) and the second parameter (k(x)), respectively; and repeating the image acquisition and the reconstructing until the first associated variance (&sgr;&bgr;(x)) and the second associated variance (&sgr;k(x)) are equal to or less than the first target variance (&sgr;&bgr;,T(x)) and the second target variance (&sgr;&bgr;,T(x)), respectively, &sgr;&bgr;(x)≦̸&sgr;&bgr;,T(x) and &sgr;k(x)≦̸&sgr;&bgr;,T(x). The method enables patient-specific adaptive protocols within molecular imaging.