公开(公告)号：EP3389716A1

公开(公告)日：2018-10-24

申请号：EP16810437.0

申请日：2016-12-19

申请人： Photocure ASA

发明人： HESTDAL, Kjetil ,  GODAL, Aslak

IPC分类号： A61K41/00 ,  A61P35/00

CPC分类号： A61K41/0061

摘要： This invention relates to a method of photodynamic therapy (PDT) for bladder cancer and its use as an adjuvant or neoadjuvant therapy in the treatment of bladder cancer. The invention provides a composition comprising hexyl 5-ALA ester (HAL) or a pharmaceutically acceptable salt thereof for use in a method of photodynamic therapy for bladder cancer, wherein said composition is instilled into the bladder of a patient in need of such treatment and the inside of said bladder is exposed to blue light having a fluence rate of 1.5 to 12.5 mW/cm2

公开(公告)号：EP3389717A1

公开(公告)日：2018-10-24

申请号：EP16819894.3

申请日：2016-12-19

申请人： Photocure ASA

发明人： HESTDAL, Kjetil

IPC分类号： A61K41/00 ,  A61P35/00

CPC分类号： A61K41/0061

摘要： This invention relates to a neoadjuvant therapy for bladder cancer in bladder cancer patients who are scheduled for a cystectomy and methods of carrying out such a neoadjuvant therapy. In particular the invention relates to a composition comprising hexyl 5-ALA ester (HAL) or a pharmaceutically acceptable salt thereof for use in a neoadjuvant therapy for bladder cancer in a bladder cancer patient who is scheduled for a cystectomy, the therapy comprises instilling said composition into the bladder of said patient and exposing the inside of said bladder to light.

公开(公告)号：EP3390448A1

公开(公告)日：2018-10-24

申请号：EP16819062.7

申请日：2016-12-19

申请人： Photocure ASA

发明人： HESTDAL, Kjetil

IPC分类号： C07K16/28 ,  A61K39/00

CPC分类号： C07K16/2818 ,  A61K2039/54 ,  C07K16/2827

摘要： This invention relates to an intravesical therapy for bladder cancer.