公开(公告)号：EP2183408A2

公开(公告)日：2010-05-12

申请号：EP08795101.8

申请日：2008-08-07

申请人： President and Fellows of Harvard College

发明人： WEITZ, David, A. ,  HOLTZE, Christian ,  ABATE, Adam, R. ,  LEE, Daeyeon ,  DO, Thao

IPC分类号： C23C18/12

CPC分类号： C23C18/1295 ,  C03C1/008 ,  C23C18/1216 ,  C23C18/1233 ,  C23C18/1254 ,  Y10T428/2457 ,  Y10T428/24612 ,  Y10T428/24744

摘要： The present invention provides a method for coating metal oxide on a PDMS surface. The method includes preparing a mixture that contains a sol-gel precursor, reacting the mixture to form a preconverted sol-gel precursor, where the preconverted sol-gel precursor does not diffuse into PDMS and is not in the form of a gel, forming a reactive PDMS surface, applying the preconverted sol-gel precursor onto the reactive PDMS surface, binding the preconverted sol-gel precursor to the reactive PDMS surface, and converting the bound preconverted sol-gel precursor to a metal oxide to form a metal oxide coating on the PDMS surface. The present invention also provides a PDMS microfiuidic device where one or more channels of the microfluidic device is provided with a metal oxide coating covalently bound only on the surface of the one or more channels.