摘要:
Efficient fluorescence detection is achieved by optically guiding fluorescence light generated by color centers within a sample to photodetectors outside the sample. A fluorescence detection system may use a sample containing one or more fluorescence color centers that emit fluorescent light when irradiated with excitation light from an optical source. The sample has an index of refraction greater than its surrounding medium. The sample may include one or more output faces and further include at least two opposing faces configured to internally reflect the fluorescent light emitted by the fluorescent color centers, and to optically guide the emitted fluorescent light to the one or more output faces. The fluorescence detection system may include one or more optical detector configured to receive fluorescent light emitted through the one or more output faces, and a microwave source configured to manipulate the electronic spin of the fluorescent color centers.
摘要:
Absorption based detection of spin states of spin impurities within a solid-state spin system, such as NV centers in diamond, is implemented by measuring the absorption intensity of an optical signal applied to the spin impurities, i.e. change in intensity of the optical signal after the signal has been transmitted through the solid-state spin system. During optical excitation of the spin impurities, microwave pulses are applied to the sample at a frequency tuned to the ESR frequency. The relative populations of the spin states of the impurities, which provides information regarding variables of interest such as an external magnetic field or a quantum information protocol, is determined from the ratio of the absorption intensity of the optical signal when the microwave pulses are turned on, to the absorption intensity of the optical signal when the microwave pulses turned off.
摘要:
The present invention generally relates to compositions, systems and methods for inducing nuclear hyperpolarization in imaging agents after they have been introduced into a subject.