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公开(公告)号：EP0859852B1
公开(公告)日：2008-09-17
申请号：EP96942722.8
申请日：1996-10-31
申请人： Prodigene, Inc.
发明人： HOWARD, John, A. , BASZCYNSKI, Chris , CZAPLA, Thomas , HOOD, Elizabeth , MEYER, Terry, EuClaire , PETERSON, David , RAO, A., Gururaj , REGISTER, James, C., III , WITCHER, Derrick
CPC分类号： C07K14/8117 , C12N15/8257 , C12N15/8286 , Y02A40/162
摘要： A method for commercial production of aprotinin entails heterologous expression of the protein in plants, preferably at a level such that aprotinin accounts for at least 0.1% of the total extracted protein. An aprotinin-expressing plant also has potential of increased insecticidal resistance by virtue of producing the protein. A genetic map of the integration locus allows identification of plants derived from the transgenic plant. This approach also reveals genetic loci on a plant chromosome that support high levels of gene expression and can be used as site of integration for expression of other genes of interest.
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公开(公告)号：EP0859852A1
公开(公告)日：1998-08-26
申请号：EP96942722.0
申请日：1996-10-31
申请人： Prodigene
发明人： HOWARD, John, A. , BASZCYNSKI, Chris , CZAPLA, Thomas , HOOD, Elizabeth , MEYER, Terry, EuClaire , PETERSON, David , RAO, A., Gururaj , REGISTER, James, C., III , WITCHER, Derrick
CPC分类号： C07K14/8117 , C12N15/8257 , C12N15/8286 , Y02A40/162
摘要： A method for commercial production of aprotinin entails heterologous expression of the protein in plants, preferably at a level such that aprotinin accounts for at least 0.1% of the total extracted protein. An aprotinin-expressing plant also has potential of increased insecticidal resistance by virtue of producing the protein. A genetic map of the integration locus allows identification of plants derived from the transgenic plant. This approach also reveals genetic loci on a plant chromosome that support high levels of gene expression and can be used as site of integration for expression of other genes of interest.
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