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1.发明公开
公开(公告)号：EP4015644A1
公开(公告)日：2022-06-22
申请号：EP21211779.0
申请日：2019-10-03
申请人： Promega Corporation
摘要： Provided herein are compositions and methods for stabilizing coelenterazine and analogs or derivatives thereof, and for improving the solubility and reconstitution efficiency of coelenterazine and analogs and derivatives thereof.
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公开(公告)号：EP4177261A1
公开(公告)日：2023-05-10
申请号：EP22182344.6
申请日：2014-03-13
申请人： Promega Corporation
发明人： Dixon, Andrew S. , Encell, Lance , Hall, Mary , Wood, Keith , Wood, Monika , Schwinn, Marie , Binkowski, Brock F. , Zegzouti, Hicham , Nath, Nidhi , Mondal, Subhanjan , Goueli, Said , Meisenheimer, Poncho , Kirkland, Thomas , Unch, James , Pulukkunat, Dileep K. , Robers, Matthew , Dart, Melanie , Machleidt, Thomas
IPC分类号： C07K14/435 , G01N33/50
摘要： Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural complementation with another, complementary non-luminescent peptide.
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公开(公告)号：EP4169935A1
公开(公告)日：2023-04-26
申请号：EP22196592.4
申请日：2014-03-13
申请人： Promega Corporation
发明人： Dixon, Andrew S. , Encell, Lance P. , Hall, Mary P. , Wood, Keith V. , Wood, Monika G. , Schwinn, Marie , Binkowski, Brock , Zegzouti, Hicham , Nath, Nidhi , Mondal, Subhanjan , Goueli, Said , Meisenheimer, Poncho , Kirkland, Thomas , Unch, James , Pulukkunat, Dileep K. , Robers, Matthew B. , Dart, Melanie , Machleidt, Thomas
IPC分类号： C07K14/435 , G01N33/50
摘要： Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural complementation with another, complementary non-luminescent peptide.
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