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1.发明授权Luminogenic and fluorogenic compounds and methods to detect molecules or conditions 有权和用于检测分子或痛苦的发光的，荧光化合物和方法
公开(公告)号：EP1935986B1
公开(公告)日：2014-04-16
申请号：EP08151520.7
申请日：2006-05-31
申请人： PROMEGA CORPORATION
发明人： Cali, James J. , Daily, William , Hawkins, Erika , Klaubert, Dieter , Liu, Jianquan , Meisenheimer, Poncho , Scurria, Michael , Shultz, John W. , Unch, James , Wood, Keith V. , Zhou, Wenhui , Valley, Michael P.
IPC分类号： C12Q1/66 , C07D277/66
CPC分类号： C07D277/66 , C12Q1/66 , G01N2500/00
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2.发明公开Luminogenic and fluorogenic compounds and methods to detect molecules or conditions 有权发光和荧光化合物和检测分子或条件的方法
公开(公告)号：EP2272973A1
公开(公告)日：2011-01-12
申请号：EP10075501.6
申请日：2006-05-31
申请人： Promega Corporation
发明人： Cali, James J. , Daily, William , Hawkins, Erica , Klaubert, Dieter , Liu, Jianquan , Meisenheimer, Poncho , Scurria, Michael , Shultz, John W. , Unch, James , Wood, Keith V. , Zhou, Wenhui , Valley, Michael P.
IPC分类号： C12Q1/66 , C07D277/66
CPC分类号： C07D277/66 , C07D277/68 , C07D311/16 , C07D417/04 , C07D417/14 , C07D493/10 , C07F9/65583 , C09B11/24 , C09B19/00 , C09B57/00 , C09B57/02 , C12Q1/66 , G01N2500/00
摘要： A method to detect the presence or amount of at least one molecule in a sample which employs a derivative of luciferin or a derivative of a fluorophore is provided.
摘要翻译： 提供了检测采用荧光素衍生物或荧光团衍生物的样品中至少一种分子的存在或量的方法。
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3.发明公开Luminogenic and fluorogenic compounds and methods to detect molecules or conditions 审中-公开和用于检测分子或痛苦的发光的，荧光化合物和方法
公开(公告)号：EP2272972A1
公开(公告)日：2011-01-12
申请号：EP10075500.8
申请日：2006-05-31
申请人： Promega Corporation
发明人： Cali, James J. , Daily, William , Hawkins, Erica , Klaubert, Dieter , Liu, Jianquan , Meisenheimer, Poncho , Scurria, Michael , Shultz, John W. , Unch, James , Wood, Keith V. , Zhou, Wenhui , Valley, Michael P.
IPC分类号： C12Q1/66 , C07D277/66
CPC分类号： C07D277/66 , C07D277/68 , C07D311/16 , C07D417/04 , C07D417/14 , C07D493/10 , C07F9/65583 , C09B11/24 , C09B19/00 , C09B57/00 , C09B57/02 , C12Q1/66 , G01N2500/00
摘要： A method to detect the presence or amount of at least one molecule in a sample which employs a derivative of luciferin or a derivative of a fluorophore is provided.
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公开(公告)号：EP4177261A1
公开(公告)日：2023-05-10
申请号：EP22182344.6
申请日：2014-03-13
申请人： Promega Corporation
发明人： Dixon, Andrew S. , Encell, Lance , Hall, Mary , Wood, Keith , Wood, Monika , Schwinn, Marie , Binkowski, Brock F. , Zegzouti, Hicham , Nath, Nidhi , Mondal, Subhanjan , Goueli, Said , Meisenheimer, Poncho , Kirkland, Thomas , Unch, James , Pulukkunat, Dileep K. , Robers, Matthew , Dart, Melanie , Machleidt, Thomas
IPC分类号： C07K14/435 , G01N33/50
摘要： Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural complementation with another, complementary non-luminescent peptide.
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公开(公告)号：EP1935986A8
公开(公告)日：2008-11-12
申请号：EP08151520.7
申请日：2006-05-31
申请人： PROMEGA CORPORATION
发明人： Cali, James J. , Daily, William , Hawkins, Erica , Klaubert, Dieter , Liu, Jianquan , Meisenheimer, Poncho , Scurria, Michael , Shultz, John W. , Unch, James , Wood, Keith V. , Zhou, Wenhui , Valley, Michael P.
IPC分类号： C12Q1/66 , C07D277/66
CPC分类号： C07D277/66 , C12Q1/66 , G01N2500/00
摘要： A method to detect the presence or amount of at least one molecule in a sample which employs a derivative of luciferin or a derivative of a fluorophore is provided.
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6.发明授权Luminogenic and fluorogenic compounds and methods to detect molecules or conditions 有权和用于检测分子或痛苦的发光的，荧光化合物和方法
公开(公告)号：EP2272973B1
公开(公告)日：2015-05-27
申请号：EP10075501.6
申请日：2006-05-31
申请人： Promega Corporation
发明人： Cali, James J. , Daily, William , Hawkins, Erika , Klaubert, Dieter , Liu, Jianquan , Meisenheimer, Poncho , Scurria, Michael , Shultz, John W. , Unch, James , Wood, Keith V. , Zhou, Wenhui , Valley, Michael P.
IPC分类号： C12Q1/66 , C07D277/66
CPC分类号： C07D277/66 , C07D277/68 , C07D311/16 , C07D417/04 , C07D417/14 , C07D493/10 , C07F9/65583 , C09B11/24 , C09B19/00 , C09B57/00 , C09B57/02 , C12Q1/66 , G01N2500/00
摘要： A method to detect the presence or amount of at least one molecule in a sample which employs a derivative of luciferin or a derivative of a fluorophore is provided.
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7.发明公开Luminogenic and fluorogenic compounds and methods to detect molecules or conditions 有权荧光素荧光素酶VERBINDUNGEN UND VERFAHRENFÜRDEN NACHWEIS VONMOLEKÜLENODER LEIDEN
公开(公告)号：EP2778234A1
公开(公告)日：2014-09-17
申请号：EP14172029.2
申请日：2006-05-31
申请人： Promega Corporation
发明人： Cali, James J. , Daily, William , Hawkins, Erika , Klaubert, Dieter , Liu, Jianquan , Meisenheimer, Poncho , Scurria, Michael , Schultz, John W. , Unch, James , Wood, Keith V. , Zhou, Wenhui , Valley, Michael P
IPC分类号： C12Q1/66 , C07D277/66
CPC分类号： C07D277/66 , C07D277/68 , C07D311/16 , C07D417/04 , C07D417/14 , C07D493/10 , C07F9/65583 , C09B11/24 , C09B19/00 , C09B57/00 , C09B57/02 , C12Q1/66 , G01N2500/00
摘要： A method to detect the presence or amount of at least one molecule in a sample which employs a derivative of luciferin or a derivative of a fluorophore is provided.
摘要翻译： 提供了检测采用荧光素衍生物或荧光团的衍生物的样品中至少一种分子的存在或量的方法。
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8.发明公开Luminogenic and fluorogenic compounds and methods to detect molecules or conditions 有权和用于检测分子或痛苦的发光的，荧光化合物和方法
公开(公告)号：EP1935986A3
公开(公告)日：2008-07-09
申请号：EP08151520.7
申请日：2006-05-30
申请人： PROMEGA CORPORATION
发明人： Cali, James J. , Daily, William , Hawkins, Erica , Klaubert, Dieter , Liu, Jianquan , Meisenheimer, Poncho , Scurria, Michael , Shultz, John W. , Unch, James , Wood, Keith V. , Zhou, Wenhui , Valley, Michael P.
IPC分类号： C12Q1/66 , C07D277/66
CPC分类号： C07D277/66 , C12Q1/66 , G01N2500/00
摘要： A method to detect the presence or amount of at least one molecule in a sample which employs a derivative of luciferin or a derivative of a fluorophore is provided.
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公开(公告)号：EP4169935A1
公开(公告)日：2023-04-26
申请号：EP22196592.4
申请日：2014-03-13
申请人： Promega Corporation
发明人： Dixon, Andrew S. , Encell, Lance P. , Hall, Mary P. , Wood, Keith V. , Wood, Monika G. , Schwinn, Marie , Binkowski, Brock , Zegzouti, Hicham , Nath, Nidhi , Mondal, Subhanjan , Goueli, Said , Meisenheimer, Poncho , Kirkland, Thomas , Unch, James , Pulukkunat, Dileep K. , Robers, Matthew B. , Dart, Melanie , Machleidt, Thomas
IPC分类号： C07K14/435 , G01N33/50
摘要： Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural complementation with another, complementary non-luminescent peptide.
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公开(公告)号：EP2778234B1
公开(公告)日：2017-09-27
申请号：EP14172029.2
申请日：2006-05-31
申请人： Promega Corporation
发明人： Cali, James J. , Daily, William , Hawkins, Erika , Klaubert, Dieter , Liu, Jianquan , Meisenheimer, Poncho , Scurria, Michael , Schultz, John W. , Unch, James , Wood, Keith V. , Zhou, Wenhui , Valley, Michael P
IPC分类号： C12Q1/66 , C07D277/66
CPC分类号： C07D277/66 , C07D277/68 , C07D311/16 , C07D417/04 , C07D417/14 , C07D493/10 , C07F9/65583 , C09B11/24 , C09B19/00 , C09B57/00 , C09B57/02 , C12Q1/66 , G01N2500/00
摘要： A method to detect the presence or amount of at least one molecule in a sample which employs a derivative of luciferin or a derivative of a fluorophore is provided.
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