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1.发明公开APPARATUS, SYSTEM AND METHOD FOR DETECTION AND DELIVERY OF A MEDICINAL DOSE 审中-公开VORRICHTUNG，SYSTEM UND VERFAHREN ZUR ERKENNUNG UND VERABREICHUNG EINER MEDIZINISCHEN DOSIS
公开(公告)号：EP2557986A2
公开(公告)日：2013-02-20
申请号：EP11769386.1
申请日：2011-04-11
发明人： ARNE, Lawrence , COSTELLO, Benedict , MESTMAN, Yuriy , ROBERTSON, Timothy , SAVAGE, George , STRAND, Angela , THOMPSON, Todd , ZDEBLICK, Mark , MCALLISTER, William
CPC分类号： A61B5/4833 , A61B5/053 , A61B5/6846 , A61B2562/0214 , A61M15/0016 , A61M15/008 , A61M15/0081 , A61M15/0083 , A61M15/009 , A61M2016/0024 , A61M2016/0039 , A61M2205/13 , A61M2205/331 , A61M2205/3317 , A61M2205/332 , A61M2205/3375 , A61M2205/3569 , A61M2205/3592 , A61M2205/50 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/6009 , A61M2205/6054 , A61M2230/63 , A61M2230/65
摘要： An apparatus is disclosed as part of a system for tracking and confirming delivery of a medicinal dose to a user. The apparatus includes a detector. The detector is secured to and communicatively coupled to the user and is capable of detecting a current flow through the user's body. The current flow is produced when the user makes contact with the apparatus. The apparatus includes at least two contact areas connected to a power source where a circuit and, hence, a current path is completed through the user's body as the user makes contact with the apparatus. The current flow is detected by the detector, which is coupled to the user. Also disclosed is an apparatus for tracking and confirming delivery of a medicinal dose to a user where the apparatus includes an acoustic detector. Upon loading the dose into a chamber an acoustic vibration is generated. The vibration is detected and correlated with a current flow that is produced when the user makes contact with the apparatus. The combined event of vibration detection and current flow detection confirms that the dose is loaded and the user is in contact with the apparatus and ready to receive the dose.
摘要翻译： 公开了一种用于跟踪并确认向用户传送药用剂量的系统的一部分的装置。 该装置包括检测器。 检测器被固定并且可通信地耦合到用户，并且能够检测通过用户身体的电流。 当用户与设备接触时产生电流。 该装置包括连接到电源的至少两个接触区域，其中当用户与设备接触时，电路和因此的电流路径通过用户的身体完成。 电流由检测器检测，检测器耦合到用户。 还公开了一种用于跟踪并确认药物剂量递送给装置包括声学检测器的用户的装置。 当将剂量加载到室中时，产生声振动。 检测振动并与用户与设备接触时产生的电流相关联。 振动检测和电流检测的组合事件证实了剂量被加载并且使用者与设备接触并准备接收剂量。
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公开(公告)号：EP2531096A2
公开(公告)日：2012-12-12
申请号：EP11737772.1
申请日：2011-01-28
发明人： ZDEBLICK, Mark
CPC分类号： A61B5/0408 , A61B5/061 , A61B5/07 , A61B5/681 , A61J7/0481 , A61J2200/30 , A61J2205/60 , A61K9/20 , G06F19/00 , G06F19/3456 , H04B13/005
摘要： Sensing is carried out from locations at considerable remove from the stomach. Cooperating sensor electronics are placed at each of two wrists of the patient. The potential discomfort and inconvenience of an abdominal patch are reduced or eliminated. And alternative power sources become available.
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公开(公告)号：EP3785599A1
公开(公告)日：2021-03-03
申请号：EP20198815.1
申请日：2008-02-01
发明人： ROBERTSON, Timothy , SAVAGE, George , ZDEBLICK, Mark , BEHZADI, Yashar , COSTELLO, Benedict , FRANK, Jeremy , HAFEZI, Hooman , HANIFF, Tariq , O'REILLY, David
摘要： Ingestible event marker systems that include an ingestible event marker (i.e., an IEM) and a personal signal receiver are provided. Embodiments of the IEM include an identifier, which may or may not be present in a physiologically acceptable carrier. The identifier is characterized by being activated upon contact with a target internal physiological site of a body, such as digestive tract internal target site. The personal signal receiver is configured to be associated with a physiological location, e.g., inside of or on the body, and to receive a signal the IEM. During use, the IEM broadcasts a signal which is received by the personal signal receiver.
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公开(公告)号：EP1889198B1
公开(公告)日：2014-11-26
申请号：EP06751858.9
申请日：2006-04-28
CPC分类号： A61B5/6861 , A61B5/0028 , A61B5/0031 , A61B5/07 , A61B5/073 , A61B5/1473 , A61B5/4833 , A61B5/4839 , A61B5/681 , A61B5/7282 , A61B2560/0214 , A61B2560/0462 , A61B2562/08 , A61B2562/162 , A61J3/007 , G06F19/00 , G06K7/10168 , H01Q1/273 , Y10T29/49117
摘要： A system comprising: a control device for altering conductance; and a partial power source comprising: a first material electrically coupled to the control device; and a second material electrically coupled to the control device and electrically isolated from the first material, wherein the first and second materials are selected to provide a voltage potential difference as a result of the materials being in contact with a conducting liquid, and wherein the control device alters the conductance between the first and second materials such that the magnitude of the current flow is varied to encode information in a signal radiated by the conducting liquid and the encoded information is remotely detectable by a receiver.
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公开(公告)号：EP1833551B1
公开(公告)日：2013-02-27
申请号：EP05855382.7
申请日：2005-12-22
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公开(公告)号：EP3367386A1
公开(公告)日：2018-08-29
申请号：EP18167390.6
申请日：2007-05-02
发明人： ZDEBLICK, Mark , THOMPSON, Andrew , SAVAGE, George
IPC分类号： G16H20/10
CPC分类号： G06F19/3456 , A61B5/0002 , A61B5/0028 , A61B5/073 , A61B5/4833 , A61B5/4848 , G06F19/00 , G06F19/34 , G06F19/3418 , G06F19/345 , G06F19/3475 , G06Q10/00 , G06Q50/22 , G16H50/20 , H01M8/02 , H01M2220/10 , H04B13/005 , Y10S128/903 , Y10S128/92
摘要： Methods, systems and compositions that allow for treating a patient according to a patient customized therapeutic regimen are provided. Embodiments of the invention include obtaining dosage administration information from a patient and using the same to tailor a therapeutic regimen for the patient. Embodiments of the invention further include preparing and forwarding to the patient physical pharmaceutical dosages based on the customized therapeutic regimen.
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公开(公告)号：EP3205265A2
公开(公告)日：2017-08-16
申请号：EP17158785.0
申请日：2009-12-15
发明人： ROBERTSON, Timothy , OMIDVAR, Fataneh , ARNE, Lawrence , ROWBERRY, Kenneth , HUTCHISON, James , LEICHNER, Robert , SAVAGE, George , THOMPSON, Andrew , ZDEBLICK, Mark , KREIDLER, Marc , HAFEZI, Hooman , DUCK, Robert
IPC分类号： A61B5/05 , A61B5/048 , H04B13/00 , A61B5/00 , A61B5/0205 , A61B5/0404
CPC分类号： A61M5/1723 , A61B5/0006 , A61B5/0028 , A61B5/02055 , A61B5/0404 , A61B5/04085 , A61B5/0428 , A61B5/053 , A61B5/11 , A61B5/1112 , A61B5/145 , A61B5/14532 , A61B5/4094 , A61B2560/0209 , A61B2560/0412 , A61B2560/0468 , A61B2562/0219 , A61M5/1452 , A61M5/172 , G06F19/34 , G06F19/3418 , H04B13/005
摘要： Receivers (100, 700, 800, 900, 1000, 1520, 15105), which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.
摘要翻译： 接收器（100,700,800,900,1000,1520,15105）可以是外部的或可植入的。 本发明的接收器的方面包括以下中的一个或多个的存在：高功率低功率模块; 中介模块; 电源模块，被配置为激活和去激活到高功率处理块的一个或多个电源; 一个连接主和从块的串行外设接口总线; 和一个多用途连接器。 本发明的接收器可以被配置为接收传导传输的信号。 还提供了包括接收器的系统以及使用它们的方法。 另外公开了使用接收器与剂量递送系统协调的系统和方法。
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公开(公告)号：EP3427660A1
公开(公告)日：2019-01-16
申请号：EP18181794.1
申请日：2009-07-02
发明人： O'REILLY, David , KARPLUS, Erika , THOMPSON, Andrew , SAVAGE, George , ZDEBLICK, Mark , ROBERTSON, Timothy , ARNE, Lawrence , BEHZADI, Yashar , MOON, Gregory , BEAULIEU, Patrick
摘要： The ingestible event marker data framework provides a uniform, comprehensive framework to enable various functions and utilities related to ingestible event marker data (IEM data). The functions and utilities include data and / or information having an aspect of data derived from, collected by, aggregated by, or otherwise associated with, an ingestion event.
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公开(公告)号：EP2531099B1
公开(公告)日：2018-12-12
申请号：EP11737770.5
申请日：2011-01-28
发明人： ZDEBLICK, Mark , HUTCHISON, James , ARNE, Lawrence
IPC分类号： A61B5/04
CPC分类号： A61B5/7217 , A61B5/002 , A61B5/04 , A61B5/0408 , A61B5/061 , A61B5/07 , A61B5/681 , A61B5/6824 , A61B5/7225 , A61B5/725 , A61B2560/0247 , A61B2562/0209 , A61B2562/04 , A61B2562/182 , A61J7/0418 , A61J7/0481 , A61J7/049 , A61J2200/30 , A61J2205/60 , A61K9/20 , G06F19/00 , G06F19/3456 , H04B13/00 , H04B13/005
摘要： A device for gathering data has first and second electrodes. The first electrode is coupled to a surface of interest, and the second electrode is coupled to “everything else” or “the air”. The first electrode is shielded from the second, and from most sources of parasitic capacitance, by a shield that is driven by an active driver that drives the shield to track, and ideally to match, the instantaneous potential of the electrode. The second electrode is likewise shielded in a similar way from most sources of parasitic capacitance. These shields likewise help to limit the extent to which RFI from the device electronics couples with either of the electrodes. In this way the sensing device achieves a markedly better signal-to-noise ratio at frequency bands of interest.
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