公开(公告)号：EP0954597A1

公开(公告)日：1999-11-10

申请号：EP96940775.0

申请日：1996-11-14

申请人： RAGLAND, William L. ,  Goodwin, Mark A. ,  Novak, Renata

发明人： RAGLAND, William L. ,  Goodwin, Mark A. ,  Novak, Renata

IPC分类号： C12Q1

CPC分类号： C12Q1/6816 ,  C12Q1/6806 ,  C12Q1/6841 ,  C12Q1/6883 ,  C12Q1/701 ,  C12Q1/703 ,  C12Q2543/10 ,  C12Q2537/161 ,  C12Q2537/1373

摘要： The present invention provides a method for detecting the presence of a predetermined infectious agent in a human or animal subject comprising obtaining a preselected portion of a whole blood sample containing at least one intact blood cell from the subject and detecting the presence of a nucleic acid from the predetermined infectious agent in the intact blood cell by nucleic acid hybridization. The preselected portion of the blood sample can include any portion which contains at least one intact blood cell, for example a peripheral blood smear or cytospin buffy coat preparation. The intact blood cell can be any blood cell including, but not limited to white blood cells and red blood cells. In one embodiment, the blood cell is a lymphocyte.

公开(公告)号：EP0238657A1

公开(公告)日：1987-09-30

申请号：EP86906571.0

申请日：1986-10-08

申请人： RAGLAND, William L.

发明人： RAGLAND, William L.

IPC分类号： A61K35 ,  A61K39

CPC分类号： A61K35/74 ,  A61K9/0019 ,  A61K9/19 ,  A61K47/02 ,  Y10S514/885 ,  Y10S514/937 ,  Y10S514/938

摘要： The present invention relates to an immunotherapeutic agent that is effective in treating a wide variety of ongoing viral infections in animals and man. The present invention is a preparation of modified mycobacterial cell walls that is capable of stimulating the immune system of an animal or man in such a way as to cause the body to neutralize, abort or eliminate an virus infection.