公开(公告)号：EP1334207A2

公开(公告)日：2003-08-13

申请号：EP01977875.2

申请日：2001-10-02

申请人： Reddy US Therapeutics, Inc.

发明人： PILLARISETTI, Sivaram ,  SAXENA, Uday ,  VINES, Angela ,  CAHOON, Shianlen

IPC分类号： C12Q1/48 ,  A61P29/00

CPC分类号： C12Q1/485 ,  C12Q1/6897 ,  G01N2333/91215

摘要： The present invention is directed to compositions and methods for treating inflammatory diseases comprising administration of compositions that effect glycogen synthase kinase 3β (GSK-3β) protein or gene. The present invention also comprises methods and compositions for the identification of compounds or therapeutic agents which modulate the activity of the protein. The present invention provides compositions for and methods off treatment of biological conditions including, but not limited to, type I and type II diabetic induced vasculopathy, other vasculopathies, asthma and inflammation-induced diseases such as atherosclerosis and cell proliferation.