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公开(公告)号:EP1732524B1
公开(公告)日:2012-08-22
申请号:EP05747062.7
申请日:2005-03-30
申请人: Relypsa, Inc.
发明人: ALPERN, Robert , BUYSSE, Jerry, M. , CHANG, Han, Ting , CHARMOT, Dominique , COPE, Michael, James , FORDTRAN, John , KLAERNER, Gerrit
CPC分类号: A61K31/78 , A61K9/14 , A61K9/1635 , A61K9/5026 , A61K9/5031 , A61K31/74 , A61K31/785 , A61K31/795 , A61K31/80 , A61K45/06 , C08F120/06 , C08F128/02 , Y10S514/838 , Y10S514/869 , Y10S514/87 , Y10S514/893
摘要: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising sodiumbinding polymers and pharmaceutical compositions thereof Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency, fluid overload, or sodium overload.
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公开(公告)号:EP1732523B1
公开(公告)日:2010-03-17
申请号:EP05732849.4
申请日:2005-03-30
申请人: Relypsa, Inc.
发明人: CHARMOT, Dominique , CHANG, Han, Ting , KLAERNER, Gerrit , COPE, Michael, James , LIU, Mingjun , LIU, Futian , MONG, Tony, Kwok-Kong
CPC分类号: A61K31/78 , A61K9/14 , A61K9/1635 , A61K9/5026 , A61K9/5031 , A61K31/74 , A61K31/785 , A61K31/795 , A61K31/80 , A61K45/06 , C08F120/06 , C08F128/02 , Y10S514/838 , Y10S514/869 , Y10S514/87 , Y10S514/893
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公开(公告)号:EP1732523B9
公开(公告)日:2010-06-02
申请号:EP05732849.4
申请日:2005-03-30
申请人: Relypsa, Inc.
发明人: CHARMOT, Dominique , CHANG, Han, Ting , KLAERNER, Gerrit , COPE, Michael, James , LIU, Mingjun , LIU, Futian , MONG, Tony, Kwok-Kong
CPC分类号: A61K31/78 , A61K9/14 , A61K9/1635 , A61K9/5026 , A61K9/5031 , A61K31/74 , A61K31/785 , A61K31/795 , A61K31/80 , A61K45/06 , C08F120/06 , C08F128/02 , Y10S514/838 , Y10S514/869 , Y10S514/87 , Y10S514/893
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