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1.发明公开MANAGEMENT METHOD AND SYSTEM FOR IMPLEMENTATION, EXECUTION, DATA COLLECTION, AND DATA ANALYSIS OF A STRUCTURED COLLECTION PROCEDURE WHICH RUNS ON A COLLECTION DEVICE 审中-公开履行，设计，数据收集和结构化集合进程的数据分析的收集设备，管理方法和系统
公开(公告)号：EP2723233A1
公开(公告)日：2014-04-30
申请号：EP12728038.6
申请日：2012-06-15
CPC分类号： A61B5/4833 , A61B5/0022 , A61B5/14532 , A61B5/4839 , A61B5/7275 , G06F19/00 , G06F19/325 , G06F19/3418 , G06F19/3456 , G16H50/20
摘要： In one embodiment, a method of performing a structured collection protocol by utilizing a collection device comprising a processor may include collecting at least one sample using the collection device. The at least one sample can be associated with biomarker data. A classification can be associated with the at least one sample via the processor. The classification can be based upon an intended use of the at least one sample. Compliance with an adherence criteria for the at least one sample can be determined via the processor. When the at least one sample is not compliant with the adherence criteria, an adherence event can be associated with the at least one sample, and the processor can perform at least one additional task that is based upon the classification associated with the at least one sample.
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2.发明公开
公开(公告)号：EP2903519A2
公开(公告)日：2015-08-12
申请号：EP13777248.9
申请日：2013-10-01
发明人： DUKE, David L. , SONI, Abhishek S.
摘要： A system and method is provided for analyzing a glucose state. A method may include identifying a target glucose state and an initial glucose state. The method may include calculating a target return path for a transition from the initial glucose state to the target glucose state. The target return path may comprise at least one intermediate glucose state associated with the transition from the initial glucose state to the target glucose state. The target return path may be calculated based on a hazard associated with the at least one intermediate glucose state of the target return path.
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3.发明授权CALIBRATION OF A HANDHELD DIABETES MANAGING DEVICE THAT RECEIVES DATA FROM A CONTINUOUS GLUCOSE MONITOR 有权校准的便携式糖尿病治疗设备接收数据从监测连续血糖监测
公开(公告)号：EP2654564B1
公开(公告)日：2016-08-17
申请号：EP11802861.2
申请日：2011-12-16
发明人： DUKE, David, L. , ENGELHARDT, Timothy, Peter , PASH, Phillip, E. , SCHMITT, Nikolaus , SONI, Abhishek S.
IPC分类号： A61B5/145
CPC分类号： A61B5/14532 , G06F19/00 , G16H40/40
摘要： A method for calibrating a handheld diabetes managing device based on data generated by a continuous glucose monitor. The method can include sampling a current of the continuous glucose monitor at a sampling interval over a time period to generate a plurality of current samples for the time period. The method can also include determining a mean, median and standard deviation of the plurality of current samples. The blood glucose level of the patient can be measured at a first time and a calibration equation that associates the plurality of current samples with the estimated glucose level of the patient based on the measured blood glucose level and the plurality of current samples can be determined when the standard deviation is less than a first threshold and an absolute value of a difference between the mean and median is less than a second threshold.
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公开(公告)号：EP2583206A2
公开(公告)日：2013-04-24
申请号：EP11725634.7
申请日：2011-06-08
发明人： SONI, Abhishek S. , GALLEY, Paul J. , GREENBURG, Alan , BOUSAMRA, Steven , WEINERT, Stefan , DIEBOLD, Eric, R.
CPC分类号： G06F19/3456 , A61B5/0002 , A61B5/14532 , A61B5/4839 , A61B5/7275 , G06F19/00 , G06F19/3418 , G06F19/3468 , G06F19/3475 , G06F19/3481 , G06Q50/24 , G16H10/20 , G16H10/60 , G16H15/00
摘要： Embodiments related to a system and method managing the implementation, execution, data collection, data analysis and status reporting of a structured collection procedure running on a portable, hand-held collection device are disclosed. The collection device performing the structured collection procedure has program instructions that when executed by a processor cause the processor to initiate automatically a schedule of events of the structured collection procedure upon one or more entry criteria being met at some unknown time, store in memory patient data collected in accordance to the schedule of events, end automatically the structured collection procedure upon one or more exit criteria being met at some unknown time. Status reporting can be provided throughout the execution of the collection procedure.
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5.发明公开SYSTEM AND METHOD CONSIDERING THE EFFECT OF PHYSICAL ACTIVITY ON THE GLUCOREGULATORY SYSTEM 有权系统和方法的体力活动对葡萄糖的监管体系的影响的光
公开(公告)号：EP2596448A1
公开(公告)日：2013-05-29
申请号：EP11748889.0
申请日：2011-07-20
发明人： SONI, Abhishek S. , BOCK, Alain , DUKE, David L.
摘要： A system and technique for modeling the effects of exercise is described that reduces the number of parameters needed to predict the effects of exercise on blood glucose levels during exercise. This exercise model includes two parameters that are readily determined, exercise sensitivity (Kex) and an inverse time constant for the exercise effect (aex). Once these parameters are determined, all that is required to model the effect of exercise is single binary input called the exercise input (Uex). Consequently, this model is independent of aerobic exercise intensity and does not require the complexity of collecting additional information during exercise, such as heart rate and venous oxygen levels. By not depending on these measures of exercise intensity, no additional measurement devices are required, which in turn results in lower costs and more patient comfort.
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6.发明公开INSULIN OPTIMIZATION SYSTEMS AND TESTING METHODS WITH ADJUSTED EXIT CRITERION ACCOUNTING FOR SYSTEM NOISE ASSOCIATED WITH BIOMARKERS 审中-公开胰岛素优化系统，并与调整的拆除标准进行测试的程序，包括与生物标志物连接系统噪声
公开(公告)号：EP2582297A1
公开(公告)日：2013-04-24
申请号：EP11730202.6
申请日：2011-06-14
CPC分类号： A61B5/14532 , G06F19/00 , G16H50/20
摘要： Embodiments of a testing method for optimizing a therapy to a diabetic patient comprise collecting at least one sampling set of biomarker data, computing a probability distribution function, a hazard function, a risk function, and a risk value for the sampling set of biomarker data, wherein the probability distribution function is calculated to approximate the probability distribution of the biomarker data, the hazard function is a function which yields higher hazard values for biomarker readings in the sampling set indicative of higher risk of complications, the risk function is the product of the probability distribution function and the hazard function, and the risk value is calculated by the integral of the risk function, minimizing the risk value by adjusting the diabetic patient's therapy, and exiting the testing method when the risk value for at least one sampling set is minimized to an optimal risk level.
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